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科研机构
山东大学 [8]
山东师范大学 [7]
上海药物研究所 [5]
上海健康医学院 [4]
西安交通大学 [2]
大连理工大学 [2]
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期刊论文 [35]
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Synthesis and structure-activity relationship studies of LLY-507 analogues as SMYD2 inhibitors
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2020, 卷号: 30, 期号: 22, 页码: 5
作者:
Zhang, Bin
;
Liao, Liping
;
Wu, Fan
;
Zhang, Fengcai
;
Sun, Zhongya
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2021/05/24
SMYD2 inhibitors
Thermal shift assay
Structure-activity relationships
Design, synthesis, and biological evaluation of tetrahydroquinolin derivatives as potent inhibitors of CBP bromodomain
期刊论文
BIOORGANIC CHEMISTRY, 2020, 卷号: 101, 页码: 11
作者:
Chen, Yu
;
Bi, Xiaoyang
;
Zhang, Fengcai
;
Sun, Zhongya
;
Xu, Pan
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2020/12/24
In silico screening
Drug design
CBP
Bromodomain
Inhibitor
Acute Myeloblastic Leukemia
Covalent Inhibitors Allosterically Block the Activation of Rho Family Proteins and Suppress Cancer Cell Invasion
期刊论文
ADVANCED SCIENCE, 2020, 页码: 13
作者:
Sun, Zhongya
;
Zhang, Hao
;
Zhang, Yuanyuan
;
Liao, Liping
;
Zhou, Wen
收藏
  |  
浏览/下载:106/0
  |  
提交时间:2020/07/01
anti-metastasis activities
crystal structures
inhibitors
novel pockets
rho family proteins
discoveryofnovelcbpbromodomaininhibitorsthroughtrfretbasedhighthroughputscreening
期刊论文
actapharmacologicasinica, 2020, 卷号: 41, 期号: 2, 页码: 285
作者:
Zhang Fengcai
;
Sun Zhongya
;
Liao Liping
;
Zuo Yu
;
Zhang Dan
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2020/07/01
CBP bromodomain
small-molecule inhibitor
high-throughput screening
TR-FRET
molecular modeling
human leukemia MV4-11 cells
Structures of Echovirus 30 in complex with its receptors inform a rational prediction for enterovirus receptor usage
期刊论文
NATURE COMMUNICATIONS, 2020, 卷号: 11, 期号: 1
作者:
Wang Kang
;
Zhu Ling
;
Sun Yao
;
Li Minhao
;
Zhao Xin
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2021/10/26
Discovery of alkoxy benzamide derivatives as novel BPTF bromodomain inhibitors via structure-based virtual screening
期刊论文
BIOORGANIC CHEMISTRY, 2019, 卷号: 86, 页码: 494-500
作者:
Zhang, Dan
;
Han, Jie
;
Lu, Wenchao
;
Lian, Fulin
;
Wang, Jun
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2020/07/01
Lysine acetylation
Bromodomain
Virtual screening
BPTF inhibitor
Torque variations of ball bearings based on dynamic model with geometrical imperfections and operating conditions
期刊论文
TRIBOLOGY INTERNATIONAL, 2019, 卷号: 133, 页码: 193-205
作者:
Zhang, Xi
;
Xu, Hua
;
Chang, Wei
;
Xi, Hui
;
Xing, Yu
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  |  
浏览/下载:117/0
  |  
提交时间:2019/11/19
Fluctuation spectrum
Friction torque
Waviness
Angular contact ball bearings
Discovery of alkoxy benzamide derivatives as novel BPTF bromodomain inhibitors via structure-based virtual screening
期刊论文
Bioorganic chemistry, 2019, 卷号: 86, 页码: 494-500
作者:
Zhang Dan[1]
;
Han Jie[2]
;
Lu Wenchao[3]
;
Lian Fulin[4]
;
Wang Jun[5]
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2019/04/22
BPTF inhibitor
Bromodomain
Lysine acetylation
Virtual screening
Platinum Nanocrystals Decorated on Defect-Rich MoS2 Nanosheets for pH-Universal Hydrogen Evolution Reaction
期刊论文
Crystal Growth and Design, 2019, 卷号: 19, 期号: 1, 页码: 60-65
作者:
Xie, Junfeng
;
Gao, Li
;
Jiang, Hailong
;
Zhang, Xiaodong
;
Lei, Fengcai
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2019/12/11
Effect of maternal antibody on the infant immune response to inactivated poliovirus vaccines made from Sabin strains.
期刊论文
Human vaccines & immunotherapeutics, 2019
作者:
Rong Tang
;
Kai Chu
;
Yuansheng Hu
;
Lei Chen
;
Ming Zhang
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/13
Inactivated
poliovirus
vaccine
Maternal
antibody
Sabin
strains
immune
response
inactivated
poliovirus
vaccine
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