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Turning single bubble sonoluminescence from blue in pure water to green by adding trace amount of carbon nanodots 期刊论文
ULTRASONICS SONOCHEMISTRY, 2021, 卷号: 78
作者:  Song, Dan;  Xu, Wen;  Luo, Man;  You, Kaijun;  Tang, Ju
收藏  |  浏览/下载：35/0  |  提交时间：2021/11/01
Influence of carbon nano-dots in water on sonoluminescence 期刊论文
NANOSCALE, 2021
作者:  Song, Dan;  Xu, Wen;  Luo, Man;  Zhang, Mingjun;  Wen, Hua
收藏  |  浏览/下载：20/0  |  提交时间：2021/09/06
The genome of Cleistogenes songorica provides a blueprint for functional dissection of dimorphic flower differentiation and drought adaptability 期刊论文
PLANT BIOTECHNOLOGY JOURNAL, 2020
作者:  Zhang, Jiyu;  Wu, Fan;  Yan, Qi;  John, Ulrik P.;  Cao, Mingshu
收藏  |  浏览/下载：23/0  |  提交时间：2020/11/25
MOF-derived hierarchical hollow spheres composed of carbon-confined Ni nanoparticles for efficient CO2 methanation 期刊论文
CATALYSIS SCIENCE & TECHNOLOGY, 2019, 卷号: 9, 页码: 731-738
作者:  Lin, Xiahui;  Wang, Sibo;  Tu, Wenguang;  Hu, Zhibiao;  Ding, Zhengxin
收藏  |  浏览/下载：20/0  |  提交时间：2019/11/21
PTPN2 induced by inflammatory response and oxidative stress contributed to glioma progression 期刊论文
JOURNAL OF CELLULAR BIOCHEMISTRY, 2019, 卷号: 120, 期号: 11
作者:  Wu, Liquan;  Wang, Fang;  Xu, Iang;  Chen, Zhibiao
收藏  |  浏览/下载：11/0  |  提交时间：2019/12/05
Study on the damage evolution of torsional fretting fatigue in a 7075 aluminum alloy 期刊论文
Wear, 2018, 卷号: 402, 页码: 160-168
作者:  Peng, Jinfang;  Jin, Xiao;  Xu, Zhibiao;  Zhang, Jun;  Cai, Zhenbing
收藏  |  浏览/下载：55/0  |  提交时间：2018/06/01
Systemic and mucosal humoral immune responses induced by the JY-adjuvanted nasal spray H7N9 vaccine in mice 期刊论文
EMERGING MICROBES & INFECTIONS, 2018, 卷号: 7
作者:  Xu, Jing;  Li, Shuxiang;  Wang, Xinyi;  Liu, Jing;  Shan, Pu
收藏  |  浏览/下载：5/0  |  提交时间：2019/12/05
Nanoparticle-enhanced synergistic HIFU ablation and transarterial chemoembolization for efficient cancer therapy 期刊论文
NANOSCALE, 2016, 卷号: 8, 期号: 7, 页码: 4324-4339
作者:  You, Yufeng;  Wang, Zhigang;  Ran, Haitao;  Zheng, Yuanyi;  Wang, Dong
收藏  |  浏览/下载：31/0  |  提交时间：2017/03/01
A modification of intraluminal middle cerebral artery occlusion/reperfusion model for ischemic stroke with laser Doppler flowmetry guidance in mice 期刊论文
NEUROPSYCHIATRIC DISEASE AND TREATMENT, 2016, 卷号: 12
作者:  Cai, Qiang;  Xu, Gang;  Liu, Junhui;  Wang, Long;  Deng, Gang
收藏  |  浏览/下载：7/0  |  提交时间：2019/12/05
Paclitaxel attenuates renal interstitial fibroblast activation and interstitial fibrosis by inhibiting STAT3 signaling 期刊论文
Drug Design, Development and Therapy, 2015, 卷号: 9, 页码: 2139-2148
作者:  Zhang, Lei;  Xu, Xuan;  Yang, Ruhao;  Chen, Jingwen;  Wang, Shixuan
收藏  |  浏览/下载：4/0  |  提交时间：2019/12/03
Recent studies have demonstrated that paclitaxel might inhibit renal fibrosis. However  the underlying molecular mechanism remains unclear. In this study  we hypothesized that low-dose paclitaxel may block the STAT3 (signal transducer and activator of transcription 3) signaling to attenuate fibrosis in a mouse model with unilateral ureteral obstruction. Both NRK-49F cells and mice with unilateral ureteral obstruction were treated with paclitaxel. The results showed that paclitaxel treatment resulted in a dose- and time-dependent decrease in tyrosine-phosphorylated STAT3  and inhibited the expression of fibronectin  alpha-smooth muscle actin (α-SMA)  and collagen I in cultured NRK-49F cells. S3I-201  an STAT3 inhibitor  also suppressed the expression of fibronectin  α-SMA  and collagen I in cultured NRK-49F cells. Mechanistically  paclitaxel treatment blocked the STAT3 activity by disrupting the association of STAT3 with tubulin and inhibiting STAT3 nucleus translocation. Furthermore  paclitaxel also ameliorated renal fibrosis by down-regulating the expression of fibronectin  α-SMA  and collagen I  and suppressed the infiltration of macrophages and production of TNF-α  IL-1β  TGF-β  and ICAM-1 (intercellular adhesion molecule 1) by inhibition of STAT3 activity in obstructive nephropathy. These results suggest that paclitaxel may block the STAT3 activity by disrupting the association of STAT3 with tubulin and inhibiting STAT3 nucleus translocation  consequently leading to the suppression of renal interstitial fibroblast activation and the development of renal fibrosis  and inhibition of proinflammatory cytokine production.  

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