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An Efficient Computational Model for Large-Scale Prediction of Protein-Protein Interactions Based on Accurate and Scalable Graph Embedding
期刊论文
FRONTIERS IN GENETICS, 2021, 卷号: 12, 期号: 2, 页码: 1-10
作者:
Su, XR (Su, Xiao-Rui)[ 1,2,3 ]
;
You, ZH (You, Zhu-Hong)[ 1,2,3 ]
;
Hu, L (Hu, Lun)[ 1,2,3 ]
;
Huang, YA (Huang, Yu-An)[ 1 ]
;
Wang, Y (Wang, Yi)[ 1,2,3 ]
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2021/05/24
large-scale
protein-protein interaction
GraphZoom
weighted graph
graph embedding
In silico drug repositioning using deep learning and comprehensive similarity measures
期刊论文
BMC BIOINFORMATICS, 2021, 卷号: 22, 期号: 增刊3, 页码: 1-14
作者:
Yi, HC (Yi, Hai-Cheng) 1 , 2
;
You, ZH (You, Zhu-Hong) 1
;
Wang, L (Wang, Lei) 1
;
Su, XR (Su, Xiao-Rui) 1 , 2
;
Zhou, X (Zhou, Xi) 1
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2021/07/14
Drug repositioningDrug-disease interactionGated recurrent unitsGaussian interaction profile kernelMachine learning
MeSHHeading2vec: a new method for representing MeSH headings as vectors based on graph embedding algorithm
期刊论文
BRIEFINGS IN BIOINFORMATICS, 2021, 卷号: 22, 期号: 2, 页码: 2085-2095
作者:
Guo,ZH (Guo, Zhen-Hao) 1
;
You,ZH (You,Zhu-Hong) 1, 2
;
Huang,DS (Huang, De-Shuang) 3, 4
;
Yi, HC (Yi, Hai-Cheng) 2
;
Zheng, K (Zheng, Kai) 5
收藏
  |  
浏览/下载:115/0
  |  
提交时间:2021/08/09
MeSHHeading2vecMeSH relationship networkgraph embeddingcomputational prediction model
Structural characterization and biological evaluation of chemical constituents from Ilex cornuta
期刊论文
JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH, 2020, 卷号: 22, 期号: 4, 页码: 316-328
作者:
Yu, SJ (Yu, Shu-Juan)[ 1,2 ]
;
Yu, ZP (Yu, Zhi-Pu)[ 1,2 ]
;
Wang, YY (Wang, Yin-Yin)[ 2 ]
;
Bao, J (Bao, Jie)[ 2 ]
;
Yuan, T (Yuan, Tao)[ 3 ]
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2020/03/16
Aquifoliaceae
Ilex cornuta
triterpenoid
triterpenoid saponin
phenolic compound
antioxidant activity
A deep learning-based method for drug-target interaction prediction based on long short-term memory neural network
期刊论文
BMC MEDICAL INFORMATICS AND DECISION MAKING, 2020, 卷号: 20, 期号: 1, 页码: 1-9
作者:
Wang, YB (Wang, Yan-Bin)[ 1,2 ]
;
You, ZH (You, Zhu-Hong)[ 1 ]
;
Yang, S (Yang, Shan)[ 1 ]
;
Yi, HC (Yi, Hai-Cheng)[ 1,2 ]
;
Chen, ZH (Chen, Zhan-Heng)[ 1,2 ]
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2020/04/21
Drug-target
Deep learning
Legendre moment
Long short-term memory
A learning based framework for diverse biomolecule relationship prediction in molecular association network
期刊论文
COMMUNICATIONS BIOLOGY, 2020, 卷号: 3, 期号: 1, 页码: 1-9
作者:
Guo, ZH (Guo, Zhen-Hao)[ 1,2 ]
;
You, ZH (You, Zhu-Hong)[ 1,2 ]
;
Huang, DS (Huang, De-Shuang)[ 3 ]
;
Yi, HC (Yi, Hai-Cheng)[ 1,2 ]
;
Chen, ZH (Chen, Zhan-Heng)[ 1,2 ]
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2020/04/21
RPI-SE: a stacking ensemble learning framework for ncRNA-protein interactions prediction using sequence information
期刊论文
BMC BIOINFORMATICS, 2020, 卷号: 21, 期号: 1, 页码: 1-10
作者:
Yi, HC (Yi, Hai-Cheng)[ 1,2 ]
;
You, ZH (You, Zhu-Hong)[ 1,2 ]
;
Wang, MN (Wang, Mei-Neng)[ 3 ]
;
Guo, ZH (Guo, Zhen-Hao)[ 1 ]
;
Wang, YB (Wang, Yan-Bin)[ 1 ]
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2020/04/21
Sequence analysis
RNA-protein interaction
ncRNA
Ensemble learning
Position weight matrix
Legendre moments
Prediction of Drug-Target Interactions From Multi-Molecular Network Based on Deep Walk Embedding Model
期刊论文
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY, 2020, 卷号: 8, 期号: 6, 页码: 1-9
作者:
Chen, ZH (Chen, Zhan-Heng)[ 1,2 ]
;
You, ZH (You, Zhu-Hong)[ 1,2 ]
;
Guo, ZH (Guo, Zhen-Hao)[ 1,2 ]
;
Yi, HC (Yi, Hai-Cheng)[ 1,2 ]
;
Luo, GX (Luo, Gong-Xu)[ 1,2 ]
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2020/09/09
drug-target interactions
molecular association network
attribute feature
behavior feature
random forest
Bioentity2vec: Attribute- and behavior-driven representation for predicting multi-type relationships between bioentities
期刊论文
GIGASCIENCE, 2020, 卷号: 9, 期号: 6, 页码: 1-12
作者:
Guo, ZH (Guo, Zhen-Hao)[ 1,2 ]
;
You, ZH (You, Zhu-Hong)[ 1,2 ]
;
Wang, YB (Wang, Yan-Bin)[ 3 ]
;
Huang, DS (Huang, De-Shuang)[ 4 ]
;
Yi, HC (Yi, Hai-Cheng)[ 1,2 ]
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2020/11/04
network biology
system biology
Bioentity2vec
multi-type relationship prediction
Triterpenoids and triterpenoid saponins from Dipsacus asper and their cytotoxic and antibacterial activities
期刊论文
PHYTOCHEMISTRY, 2019, 卷号: 162, 期号: 6, 页码: 241-249
作者:
Yu, JH (Yu, Jin-Hai)[ 1 ]
;
Yu, ZP (Yu, Zhi-Pu)[ 1,2 ]
;
Wang, YY (Wang, Yin-Yin)[ 1 ]
;
Bao, J (Bao, Jie)[ 1 ]
;
Zhu, KK (Zhu, Kong-Kai)[ 1 ]
收藏
  |  
浏览/下载:67/0
  |  
提交时间:2019/06/21
Dipsacus asper
Caprifoliaceae
Triterpenoid
Triterpenoid saponin
Cytotoxicity
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