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PGE2-JNK signaling axis non-canonically promotes Gli activation by protecting Gli2 from ubiquitin-proteasomal degradation 期刊论文
CELL DEATH & DISEASE, 2021, 卷号: 12, 期号: 7, 页码: 10
作者:  Yang, Jun;  Wang, Juan;  Liu, Yuan;  Zhang, Yu;  Huang, Wenjing
收藏  |  浏览/下载:42/0  |  提交时间:2021/08/17
Development of hedgehog pathway inhibitors by epigenetically targeting GLI through BET bromodomain for the treatment of medulloblastoma 期刊论文
ACTA PHARMACEUTICA SINICA B, 2021, 卷号: 11, 期号: 2, 页码: 488-504
作者:  
收藏  |  浏览/下载:30/0  |  提交时间:2021/05/24
Medulloblastoma: Molecular understanding, treatment evolution, and new developments 期刊论文
PHARMACOLOGY & THERAPEUTICS, 2020, 卷号: 210, 页码: 13
作者:  Liu, Xiaohua;  Ding, Chunyong;  Tan, Wenfu;  Zhang, Ao
收藏  |  浏览/下载:20/0  |  提交时间:2020/07/01
Colocalization Strategy Unveils an Underside Binding Site in the Transmembrane Domain of Smoothened Receptor 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 21, 页码: 9983-9989
作者:  Zhou, Fang;  Ding, Kang;  Zhou, Yiqing;  Liu, Yang;  Liu, Xiaoyan
收藏  |  浏览/下载:27/0  |  提交时间:2020/07/01
Development of high potent and selective Bcl-2 inhibitors bearing the structural elements of natural product artemisinin 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 159, 页码: 149-165
作者:  Liu, Xiaohua;  Zhang, Yu;  Huang, Wenjing;  Luo, Jia;  Li, Yang
收藏  |  浏览/下载:37/0  |  提交时间:2019/01/08
Discovery of novel 2,4-diarylaminopyrimidine derivatives as potent and selective epidermal growth factor receptor (EGFR) inhibitors against L858R/T790M resistance mutation 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 152, 页码: 298-306
作者:  Yan, Qi;  Chen, Yuzhe;  Tang, Baiyou;  Xiao, Qiang;  Qu, Rong
收藏  |  浏览/下载:77/0  |  提交时间:2019/01/08
Design, synthesis and pharmacological evaluation of new acyl sulfonamides as potent and selective Bcl-2 inhibitors 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2018, 卷号: 26, 期号: 2, 页码: 443-454
作者:  Liu, Xiaohua;  Zhang, Yu;  Huang, Wenjing;  Tan, Wenfu;  Zhang, Ao
收藏  |  浏览/下载:28/0  |  提交时间:2019/01/08
Discovery of novel 2,4-diarylaminopyrimidine derivatives as potent and selective epidermal growth factor receptor (EGFR) inhibitors against L858R/T790M resistance mutation 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 152
作者:  Yan, Qi;  Chen, Yuzhe;  Tang, Baiyou;  Xiao, Qiang;  Qu, Rong
收藏  |  浏览/下载:14/0  |  提交时间:2019/12/05
Design, synthesis and pharmacological evaluation of new acyl sulfonamides as potent and selective Bcl-2 inhibitors 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2018, 卷号: 26, 期号: 2
作者:  Liu, Xiaohua;  Zhang, Yu;  Huang, Wenjing;  Tan, Wenfu;  Zhang, Ao
收藏  |  浏览/下载:3/0  |  提交时间:2019/12/05
Development of high potent and selective Bcl-2 inhibitors bearing the structural elements of natural product artemisinin 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 159
作者:  Liu, Xiaohua;  Zhang, Yu;  Huang, Wenjing;  Luo, Jia;  Li, Yang
收藏  |  浏览/下载:3/0  |  提交时间:2019/12/05


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