CORC

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CORC

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Discovery of High-Affinity Inhibitors of the BPTF Bromodomain 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 16, 页码: 12075-12088
作者:  Lu, Tian;  Lu, Haibo;  Duan, Zhe;  Wang, Jun;  Han, Jie
收藏  |  浏览/下载：38/0  |  提交时间：2021/11/04
SARS-CoV-2 envelope protein causes acute respiratory distress syndrome (ARDS)-like pathological damages and constitutes an antiviral target 期刊论文
CELL RESEARCH, 2021, 页码: 14
作者:  Xia, Bingqing;  Shen, Xurui;  He, Yang;  Pan, Xiaoyan;  Liu, Feng-Liang
收藏  |  浏览/下载：78/0  |  提交时间：2021/08/17
PRMT1 is a novel molecular therapeutic target for clear cell renal cell carcinoma 期刊论文
THERANOSTICS, 2021, 卷号: 11, 期号: 11, 页码: 5387-5403
作者:  Wang, Jianfeng;  Wang, Chen;  Xu, Pan;  Li, Xiao;  Lu, Yongning
收藏  |  浏览/下载：130/0  |  提交时间：2021/05/24
Structure-based design of antiviral drug candidates targeting the SARS-CoV-2 main protease 期刊论文
SCIENCE, 2020, 卷号: 368, 期号: 6497, 页码: 1331-+
作者:  Dai, Wenhao;  Zhang, Bing;  Jiang, Xia-Ming;  Su, Haixia;  Li, Jian
收藏  |  浏览/下载：30/0  |  提交时间：2020/12/24
Structure of M-pro from SARS-CoV-2 and discovery of its inhibitors 期刊论文
NATURE, 2020, 页码: 24
作者:  Jin, Zhenming;  Du, Xiaoyu;  Xu, Yechun;  Deng, Yongqiang;  Liu, Meiqin
收藏  |  浏览/下载：41/0  |  提交时间：2020/07/01
Selective activation of TWIK-related acid-sensitive K+ 3 subunit-containing channels is analgesic in rodent models 期刊论文
SCIENCE TRANSLATIONAL MEDICINE, 2019, 卷号: 11, 期号: 519, 页码: 12
作者:  Liao, Ping;  Qiu, Yunguang;  Mo, Yiqing;  Fu, Jie;  Song, Zhenpeng
收藏  |  浏览/下载：30/0  |  提交时间：2020/07/01
Pharmacokinetics-Driven Optimization of 4(3H)-Pyrimidinones as Phosphodiesterase Type 5 Inhibitors Leading to TPN171, a Clinical Candidate for the Treatment of Pulmonary Arterial Hypertension 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 10, 页码: 4979-4990
作者:  Wang, Zhen;  Jiang, Xiangrui;  Zhang, Xianglei;  Tian, Guanghui;  Yang, Rulei
收藏  |  浏览/下载：39/0  |  提交时间：2020/07/01
The dynamic conformational landscape of the protein methyltransferase SETD8 期刊论文
ELIFE, 2019, 卷号: 8, 页码: 76
作者:  Chen, Shi;  Wiewiora, Rafal P.;  Meng, Fanwang;  Babault, Nicolas;  Ma, Anqi
收藏  |  浏览/下载：11/0  |  提交时间：2020/07/01
Pharmacokinetics-Driven Optimization of 4(3H)-Pyrimidinones as Phosphodiesterase Type 5 Inhibitors Leading to TPN171, a Clinical Candidate for the Treatment of Pulmonary Arterial Hypertension 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 10, 页码: 4979-4990
作者:  Wang, Z (Wang, Zhen)[ 1 ];  Jiang, XR (Jiang, Xiangrui)[ 1 ];  Zhang, XL (Zhang, Xianglei)[ 1,2 ];  Tian, GH (Tian, Guanghui)[ 3 ];  Yang, RL (Yang, Rulei)[ 3 ]
收藏  |  浏览/下载：137/0  |  提交时间：2019/06/28

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