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Isolation, synthesis and bioactivity evaluation of isoquinoline alkaloids from Corydalis hendersonii Hemsl. against gastric cancer in vitro and in vivo
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2022, 卷号: 60
作者:
Luo, T
;
Li, Z
;
Deng, XM
;
Jiang, K
;
Liu, D
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2022/12/02
SN38-based albumin-binding prodrug for efficient targeted cancer chemotherapy
期刊论文
JOURNAL OF CONTROLLED RELEASE, 2021, 卷号: 339, 页码: 297-306
作者:
Huang, Ying
;
Wang, Lei
;
Cheng, Zhiyang
;
Yang, Biyu
;
Yu, Jiahui
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2021/12/01
Antitumour
Chemotherapy
SN38
Drug delivery systems
Albumin
Combating liver cancer through GO-targeted biomaterials
期刊论文
BIOMEDICAL MATERIALS, 2021, 卷号: 16, 期号: 6, 页码: 14
作者:
Huang, Xing
;
Zhang, Jiaxin
;
Song, Yijie
;
Zhang, Tong
;
Wang, Bing
收藏
  |  
浏览/下载:62/0
  |  
提交时间:2021/11/04
graphene oxide
hydroxycamptothecin
anti-cancer
drug delivery system
targeting
A validated HPLC-MS/MS method for determination of simmitecan and its metabolite chimmitecan in human plasma and its application to a pharmacokinetic study in Chinese patients with advanced solid tumor
期刊论文
JOURNAL OF SEPARATION SCIENCE, 2021, 页码: 8
作者:
Zhou, Jun
;
Zhan, Yan
;
Zhong, Dafang
;
Chen, Xiaoyan
;
Zhang, Yifan
收藏
  |  
浏览/下载:72/0
  |  
提交时间:2021/11/04
chimmitecan
mass spectrometry
pharmacokinetics
simmitecan
solid tumors
Design, synthesis and bioactivity study of evodiamine derivatives as multifunctional agents for the treatment of hepatocellular carcinoma
期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 114
作者:
Fan, Xiaohong
;
Deng, Jiedan
;
Shi, Tao
;
Wen, Huaixiu
;
Li, Junfang
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2021/11/18
Hepatocellular carcinoma
Topo I
Evodiamine
Cancer-associated fibroblasts (CAFs)
Design and synthesis of novel desfluoroquinolone-aminopyrimidine hybrids as potent anti-MRSA agents with low hERG activity
期刊论文
BIOORGANIC CHEMISTRY, 2020, 卷号: 103, 页码: 10
作者:
Song, Runzhe
;
Wang, Yue
;
Wang, Minghui
;
Gao, Ruixuan
;
Yang, Teng
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2020/12/24
Desfluoroquinolone
Aminopyrimidine
Hybrids
Anti-MRSA
hERG activity
Design, Synthesis, and Biological Evaluation of HSP90 Inhibitor-SN38 Conjugates for Targeted Drug Accumulation
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 63, 期号: 10, 页码: 5421-5441
作者:
Zhu, Shulei
;
Shen, Qianqian
;
Gao, Yinglei
;
Wang, Lei
;
Fang, Yanfen
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2020/12/24
Co-Prodrugs of 7-Ethyl-10-hydroxycamptothecin and Vorinostat with in Vitro Hydrolysis and Anticancer Effects
期刊论文
ACS OMEGA, 2020, 卷号: 5, 期号: 1, 页码: 350-357
作者:
Liu, Shuangxi
;
Hu, Zonglong
;
Zhang, Qiumeng
;
Zhu, Qiwen
;
Chen, Yi
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2020/07/01
Sexual reproduction potential implied by functional analysis of SPO11 in Phaeodactylum tricornutum
期刊论文
GENE, 2020, 卷号: 757, 期号: x, 页码: -
作者:
Mao, Yufeng
;
Guo, Li
;
Luo, Yan
;
Tang, Zhihong
;
Li, Wei
收藏
  |  
浏览/下载:50/0
  |  
提交时间:2020/10/22
ARABIDOPSIS TOPOISOMERASE-VI
MEIOTIC RECOMBINATION
EVOLUTIONARY HISTORY
PROTEIN FAMILY
GENE
COMPLEX
MEIOSIS
PCR
TRANSFORMATION
ASSOCIATION
Design, Synthesis, and Biological Evaluation of Novel Biotinylated Podophyllotoxin Derivatives as Potential Antitumor Agents
期刊论文
FRONTIERS IN CHEMISTRY, 2019, 卷号: 7, 页码: 14
作者:
Zi, Cheng-Ting
;
Gao, Yin-Sheng
;
Yang, Liu
;
Feng, Shu-Yun
;
Huang, Yue
收藏
  |  
浏览/下载:80/0
  |  
提交时间:2019/07/29
podophyllotoxin derivatives
biotin
anticancer activity
synthesis
apoptosis
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