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Key Considerations in Targeted Protein Degradation Drug Discovery and Development 期刊论文
FRONTIERS IN CHEMISTRY, 2022, 卷号: 10
作者:  Qin, Liena;  Dai, Han;  Wang, Junfeng
收藏  |  浏览/下载:19/0  |  提交时间:2022/12/23
Rational Design by Structural Biology of Industrializable, Long-Acting Antihyperglycemic GLP-1 Receptor Agonists 期刊论文
PHARMACEUTICALS, 2022, 卷号: 15
作者:  Sun, Lei;  Zheng, Zhi-Ming;  Shao, Chang-Sheng;  Zhang, Zhi-Yong;  Li, Ming-Wei
收藏  |  浏览/下载:16/0  |  提交时间:2022/12/22
Natural products for infectious microbes and diseases: an overview of sources, compounds, and chemical diversities 期刊论文
SCIENCE CHINA-LIFE SCIENCES, 2022, 卷号: 65, 期号: 6, 页码: 1123-1145
作者:  Luo, Lu;  Yang, Jun;  Wang, Cheng;  Wu, Jie;  Li, Yafang
收藏  |  浏览/下载:0/0  |  提交时间:2024/03/07
Transformer-Based Generative Model Accelerating the Development of Novel BRAF Inhibitors 期刊论文
ACS OMEGA, 2021, 卷号: 6, 期号: 49, 页码: 33864-33873
作者:  Yang, Lijuan;  Yang, Guanghui;  Bing, Zhitong;  Tian, Yuan;  Niu, Yuzhen
收藏  |  浏览/下载:16/0  |  提交时间:2022/04/11
Rational Design and Development of Novel CDK9 Inhibitors for the Treatment of Acute Myeloid Leukemia 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 19, 页码: 14647-14663
作者:  Han, Xu;  Song, Ning;  Saidahmatov, Abdusaid;  Wang, Peipei;  Wang, Yong
收藏  |  浏览/下载:17/0  |  提交时间:2021/12/16
Structural basis for ligand recognition of the neuropeptide Y Y-2 receptor 期刊论文
NATURE COMMUNICATIONS, 2021, 卷号: 12, 期号: 1, 页码: 9
作者:  Tang, Tingting;  Hartig, Christin;  Chen, Qiuru;  Zhao, Wenli;  Kaiser, Anette
收藏  |  浏览/下载:41/0  |  提交时间:2021/05/24
What coronavirus 3C-like protease tells us: From structure, substrate selectivity, to inhibitor design 期刊论文
MEDICINAL RESEARCH REVIEWS, 2021, 页码: 34
作者:  Xiong, Muya;  Su, Haixia;  Zhao, Wenfeng;  Xie, Hang;  Shao, Qiang
收藏  |  浏览/下载:42/0  |  提交时间:2021/05/24
DrugSpaceX: a large screenable and synthetically tractable database extending drug space 期刊论文
NUCLEIC ACIDS RESEARCH, 2021, 卷号: 49, 期号: D1, 页码: D1170-D1178
作者:  Yang, Tianbiao;  Li, Zhaojun;  Chen, Yingjia;  Feng, Dan;  Wang, Guangchao
收藏  |  浏览/下载:55/0  |  提交时间:2021/05/24
Dynamic folding modulation generates FGF21 variant against diabetes 期刊论文
EMBO REPORTS, 2021, 卷号: 22
作者:  Zhu, Lei;  Zhao, Hongxin;  Liu, Juanjuan;  Cai, Hao;  Wu, Bo
收藏  |  浏览/下载:25/0  |  提交时间:2021/08/30
Discovery and Optimization of Non-bile Acid FXR Agonists as Preclinical Candidates for the Treatment of Nonalcoholic Steatohepatitis 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 63, 期号: 21, 页码: 12748-12772
作者:  Li, Junyou;  Liu, Mengqi;  Li, Yazhou;  Sun, Dan-dan;  Shu, Zhihao
收藏  |  浏览/下载:22/0  |  提交时间:2021/05/24


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