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上海药物研究所 [58]
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JC-010a, a novel selective SHP2 allosteric inhibitor, overcomes RTK/non-RTK-mediated drug resistance in multiple oncogene-addicted cancers
期刊论文
CANCER LETTERS, 2024, 卷号: 582, 页码: 15
作者:
Lu, Xuxiu
;
Yu, Rilei
;
Li, Zhen
;
Yang, Mengke
;
Dai, Jiajia
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2024/04/07
Acquired resistance
Cancer
NSCLC
JC-010a
SHP2
Predicting and overcoming resistance to CDK9 inhibitors for cancer therapy
期刊论文
ACTA PHARMACEUTICA SINICA B, 2023, 卷号: 13
作者:
Hua, Chen
;
Shena, Lijuan
;
Zoua, Fengming
;
Wua, Yun
;
Wanga, Beilei
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2023/11/10
Acquired resistance mutations
CDK9 inhibitors
Transcription
Single nucleotide polymorphisms
BAY1251152
Simulating androgen receptor selection in designer yeast
期刊论文
SYNTHETIC AND SYSTEMS BIOTECHNOLOGY, 2022, 卷号: 7
作者:
Zhang, Haoran
;
Zhang, Lu
;
Xu, Yipeng
;
Chen, Shaoyong
;
Ma, Zhenyi
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2022/12/23
Androgen receptor mutations
Androgen receptor antagonists
Prostate cancer
Saccharomyces cerevisiae
CEF3 is involved in membrane trafficking and essential for secondary cell wall biosynthesis and its mutation enhanced biomass enzymatic saccharification in rice
期刊论文
BIOTECHNOLOGY FOR BIOFUELS AND BIOPRODUCTS, 2022, 卷号: 15
作者:
Jiang, Hongrui
;
Ren, Yan
;
Guo, Junyao
;
Yang, Huijie
;
Zhu, Xiaotong
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  |  
浏览/下载:18/0
  |  
提交时间:2022/12/23
Secondary cell wall (SCW)
Rice
Cellulose biosynthesis
Biomass
Saccharification
membrane trafficking
Map-based cloning
Impact of clinical and molecular features on efficacy and outcome of patients with non-small cell lung cancer receiving second-line osimertinib
期刊论文
BMC CANCER, 2022, 卷号: 22
作者:
Jin, Ying
;
Lin, Chen
;
Shi, Xun
;
He, Qiong
;
Yan, Junrong
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2022/12/23
Clinical and molecular features
Efficacy and outcome
EGFR T790M mutation
Non-small-cell lung cancer
Osimertinib
Effect of Cold-Heat Treatment on Structure and Properties of Zr-Based Bulk Amorphous Alloys
期刊论文
RARE METAL MATERIALS AND ENGINEERING, 2022, 卷号: 51, 期号: 5, 页码: 1759-1766
作者:
Wang Shunping
;
Li Chunyan
;
Wang Haibo
;
Li Jinling
;
Li Yang
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2022/07/19
bulk metallic glass
cold-heat treatment
microstructure
mechanical properties
corrosion resistance
PtoMPO1, a negative mediator, functions in poplar drought tolerance
期刊论文
PLANT PHYSIOLOGY AND BIOCHEMISTRY, 2022, 卷号: 190, 页码: 156-163
作者:
Zheng, Min
;
Lei, Shikang
;
Liu, Yun
;
Feng, Dalan
;
Huang, Xiaohui
收藏
  |  
浏览/下载:0/0
  |  
提交时间:2024/03/07
AtMHP1
Drought stress
Poplar
PtoMPO1
Identification and Fine Mapping of the Recessive Gene BK-5, Which Affects Cell Wall Biosynthesis and Plant Brittleness in Maize
期刊论文
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2022, 卷号: 23, 期号: 2
作者:
Li, Qigui
;
Nie, Shujun
;
Li, Gaoke
;
Du, Jiyuan
;
Ren, Ruchang
收藏
  |  
浏览/下载:0/0
  |  
提交时间:2024/03/07
maize
brittle stalk
cell wall
cellulose synthase catalytic subunit (CESA)
A reference-guided TILLING by amplicon-sequencing platform supports forward and reverse genetics in barley
期刊论文
PLANT COMMUNICATIONS, 2022, 卷号: 3, 期号: 4
作者:
Jiang, Congcong
;
Lei, Miaomiao
;
Guo, Yu
;
Gao, Guangqi
;
Shi, Lijie
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2024/03/07
barley
mutagenesis
TILLING
amplicon-seq
genetics
Clinical outcomes of lung adenocarcinoma patients harboring uncommon epidermal growth factor receptor (EGFR) mutations treated with EGFR-tyrosine kinase inhibitors (TKIs)
期刊论文
ANNALS OF PALLIATIVE MEDICINE, 2021
作者:
Si, Jinfei
;
Gu, Xiaodong
;
Wang, Wenxian
;
Ying, Shenpeng
;
Song, Zhengbo
收藏
  |  
浏览/下载:59/0
  |  
提交时间:2022/02/14
Epidermal growth factor receptor (EGFR)
uncommon mutation
compound mutation
double uncommon mutation
lung adenocarcinoma (lung AC)
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