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Prediction of Ticagrelor and its Active Metabolite in Liver Cirrhosis Populations Using a Physiologically Based Pharmacokinetic Model Involving Pharmacodynamics 期刊论文
JOURNAL OF PHARMACEUTICAL SCIENCES, 2019, 卷号: 108, 期号: 8
作者:  Zhang, Min;  You, Xiang;  Ke, Meng;  Jiao, Zheng;  Wu, Hongwei
收藏  |  浏览/下载:17/0  |  提交时间:2019/12/05
Glycyrrhizin has a high likelihood to be a victim of drug-drug interactions mediated by hepatic organic anion-transporting polypeptide 1B1/1B3 期刊论文
BRITISH JOURNAL OF PHARMACOLOGY, 2018, 卷号: 175, 期号: 17, 页码: 3486-3503
作者:  Dong, Jiajia;  Olaleye, Olajide E.;  Jiang, Rongrong;  Li, Jing;  Lu, Chuang
收藏  |  浏览/下载:100/0  |  提交时间:2019/01/08
Prediction of Drug-Drug Interactions with Bupropion and Its Metabolites as CYP2D6 Inhibitors Using a Physiologically-Based Pharmacokinetic Model 期刊论文
PHARMACEUTICS, 2018, 卷号: 10, 期号: 1
作者:  Xue, Caifu;  Zhang, Xunjie;  Cai, Weimin
收藏  |  浏览/下载:3/0  |  提交时间:2019/12/05
Novel in vitro dynamic metabolic system for predicting the human pharmacokinetics of tolbutamide 期刊论文
ACTA PHARMACOLOGICA SINICA, 2018, 卷号: 39, 期号: 9
作者:  Cai-fu Xue;  Zhe Zhang;  Yan Jin;  Bin Zhu;  Jun-fen Xing
收藏  |  浏览/下载:3/0  |  提交时间:2019/12/05
Development of a Physiologically Based Pharmacokinetic Model for Sinogliatin, a First-in-Class Glucokinase Activator, by Integrating Allometric Scaling, In Vitro to In Vivo Exploration and Steady-State Concentration-Mean Residence Time Methods: M 期刊论文
2018, 卷号: 57, 期号: 10, 页码: 1307-1323
作者:  Song, Ling;  Zhang, Yi;  Jiang, Ji;  Ren, Shuang;  Chen, Li
收藏  |  浏览/下载:5/0  |  提交时间:2020/01/03
Comment on: "A Physiologically Based Pharmacokinetic Drug-Disease Model to Predict Carvedilol Exposure in Adult and Paediatric Heart Failure Patients by Incorporating Pathophysiological Changes in Hepatic and Renal Blood" 期刊论文
CLINICAL PHARMACOKINETICS, 2016, 卷号: 55, 期号: 1
作者:  Li, Guo-Fu;  Gu, Xiao;  Yu, Guo;  Zhao, Shui-Yu;  Zheng, Qing-Shan
收藏  |  浏览/下载:10/0  |  提交时间:2019/12/05
Uncertainty analysis in 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) cancer dose-response for three occupational cohorts 期刊论文
ENVIRONMENT INTERNATIONAL, 2016
Dong, Zhaomin; Yuan, Guanxiang; Hu, Jianying
收藏  |  浏览/下载:5/0  |  提交时间:2017/12/03
Comment on: "A Physiologically Based Pharmacokinetic Drug-Disease Model to Predict Carvedilol Exposure in Adult and Paediatric Heart Failure Patients by Incorporating Pathophysiological Changes in Hepatic and Renal Blood" 期刊论文
Clinical pharmacokinetics, 2016, 卷号: 55, 页码: 133-7
作者:  Li Guo-Fu[1];  Gu Xiao[2];  Yu Guo[3];  Zhao Shui-Yu[4];  Zheng Qing-Shan[5]
收藏  |  浏览/下载:2/0  |  提交时间:2019/04/26
Evaluating a physiologically based pharmacokinetic model for predicting the pharmacokinetics of midazolam in Chinese after oral administration 期刊论文
2016, 卷号: 37, 期号: 2, 页码: 276-84
作者:  Wang Hong-yun;  Chen Xia;  Jiang Ji;  Shi Jun;  Hu Pei
收藏  |  浏览/下载:2/0  |  提交时间:2020/01/04
Application of a physiologically based pharmacokinetic model for the evaluation of single-point plasma phenotyping method of CYP2D6 期刊论文
2016, 卷号: 92, 页码: 131-6
作者:  Chen Rui;  Rostami-Hodjegan Amin;  Wang Haotian;  Berk David;  Shi Jun
收藏  |  浏览/下载:5/0  |  提交时间:2020/01/04


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