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CORC

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IMM-H004 therapy for permanent focal ischemic cerebral injury via CKLF1/CCR4-mediated NLRP3 inflammasome activation 期刊论文
2019, 卷号: 212, 页码: 36-53
作者:  Ai Q D;  Chen Chen;  Chu Shifeng;  Zhang Zhao;  Luo Yun
收藏  |  浏览/下载：26/0  |  提交时间：2020/01/03
ASC = apoptosis-associated speck-like protein containing a caspase activation recruitment domain  BCA = bicinchoninic acid  BSA = bovine serum albumin  CCA = common carotid artery  CCR4 = C-C chemokine receptor type 4  CKLF1 = chemokine-like factor 1  CO-IP = coimmunoprecipitation  ECA = external carotid artery  ELISA = enzyme-linked immunosorbent assay  FDA = Food and Drug Administration  I/R = ischemic/reperfusion  ICA = internal carotid artery  IL-18 = interleukin 18  IL-1β = interleukin 1β  LDH = lactate dehydrogenase  NLRP3 = NOD-like receptor protein 3  PBS = phosphate-buffered saline  SD = standard deviation  TNF-α = tumor necrosis factor α  TTC = 2  3  5-triphenyltetrazolium-chloride  WT = wild-type  pMCAO = permanent middle cerebral artery occlusion  pro-Caspase-1 = precursor Caspase-1  qPCR = quantitative real-time PCR  tMCAO = transient middle cerebral artery occlusion  tPA = tissue plasminogen activator  
NK cells in cerebral ischemia 期刊论文
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2019, 卷号: 109, 页码: 547-554
作者:  Chen, Chen;  Ai, Qi-Di;  Chu, Shi-Feng;  Zhang, Zhao;  Chen, Nai-Hong*
收藏  |  浏览/下载：35/0  |  提交时间：2019/12/27
tPA  tissue plasminogen activator  IS  ischemic stroke  BBB  blood-brain barrier  IFN-γ  interferon-γ  pMCAO  permanent middle cerebral artery occlusion  tMCAO  transient middle cerebral artery occlusion  CX3CR1  CX3CL1 receptor  CNS  central nervous system  AchE  acetylcholine esterase  CFSE  arboxyfluorescein diacetate succinimidyl ester  HI  hypoxic ischemia  MCAO IP-10  interferon-inducible protein-10  IL  interleukin  GFAP  glial fibrillary acidic protein  tg  transgenic  WT  wild-type  APC  antigen presenting cell  SAI  stroke-associated infection  STAT3  signal transducer and activator of transcription-3  HPA  hypothalamic-pituitary-adrenal  cSVD  cerebral small vessel disease  SHR  spontaneously hypertensive rat  CSF  cerebrospinal fluid  aSAH  aneurysmal subarachnoid hemorrhage  DCI  delayed cerebral ischemia  MRI  magnetic resonance imaging  CT  computed tomography  EVs  extracellular vesicles  MSC  mesenchymal stem cell  MNCs  bone marrow-derived mononuclear cells  CpG-ODN  cytosine-guanine oligodideoxynucleotide  TLR9  toll-like receptor 9  TNF  tumor necrosis factor  NK cells  Cerebral ischemia  Inflammation  Immunodpression  Infection  
Chemokines play complex roles in cerebral ischemia 期刊论文
Neurochemistry International, 2018, 卷号: 112, 页码: 146-158
作者:  Chen, Chen;  Chu, Shi-Feng;  Liu, Dan-Dan;  Zhang, Zhao;  Kong, Ling-Lei
收藏  |  浏览/下载：32/0  |  提交时间：2019/12/27
Chemokine  Cerebral ischemia  Ischemic stroke  IS  ischemic stroke  NSCs  neural stem cell  NPCs  neural progenitor cells  BMSCs  bone marrow stromal cells  ELR  glutamic acid-leucine-arginine  MCP  monocytes chemoattractant protein  MCAo  middle cerebral artery occlusion  tMCAo  transient MCAo  CNS  central nervous system  MIP  macrophage inflammatory protein  BBB  blood brain barrier  HI  hypoxia ischemia  CSF  cerebrospinal fluid  CI  cerebral infarction  WT  wildtype  pMCAo  permanent MCAo  ET  endothelin  I/R  ischemia/reperfusion  SCID  Severe Combined Immunodeficiency  ENA-78  epithelial neutrophil-activating peptide-78  IL-8  interleukin 8  PMNL  polymorphonuclear leukocyte  MSCs  mesenchymal stem cells  VEGF  vascular endothelial growth factor  CINC  cytokine-induced neutrophil chemoattractant  IP-10  interferon-gamma inducible protein-10  NK  natural killer  SDF-1  stromal cell-derived factor-1  EPCs  endothelial progenitor cells  HSCs  hematopoietic stem cells  HUVECs  human umbilical vein endothelial cells  TIA  transient ischemic attack  OGD  oxygen glucose deprivation  GPCs  glial precursor cells  CMKLR1  chemerin-like receptor-1  AIS  acute ischemic stroke  CKLF1  chemokine-like factor 1  CBP  chemokine-binding protein  
Effects of Dl-3-n-butylphthalide on Cerebral Ischemia Infarction in Rat Model by Mass Spectrometry Imaging 期刊论文
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2017, 卷号: 18, 期号: 11
作者:  Liu, Run-Zhe;  Fan, Chao-Xin;  Zhang, Zhi-Lin;  Zhao, Xin;  Sun, Yi
收藏  |  浏览/下载：31/0  |  提交时间：2019/04/09
Bilobalide inhibits the expression of aquaporin 1,4 and glial fibrillary acidic protein in rat brain tissue after permanent focal cerebral ischemia 期刊论文
NEURAL REGENERATION RESEARCH, 2011, 卷号: 6, 期号: 27, 页码: 2105-2111
作者:  Qin Haiming;  Song Fulin;  Han Hongguang
收藏  |  浏览/下载：0/0  |  提交时间：2021/02/26
用阿托伐他汀保护急性脑缺血大鼠脑的研究 期刊论文
第四军医大学学报, 2008, 期号: 7, 页码: 619-622
作者:  陈凤;  王江昆;  王德贵;  侯一平;  宋焱峰
收藏  |  浏览/下载：2/0  |  提交时间：2016/09/09
延迟亚低温治疗对大鼠永久性大脑中动脉阻塞后凋亡相关蛋白表达的影响 期刊论文
中风与神经疾病杂志, 2008, 卷号: 25, 期号: 1
作者:  吕佳宁(1);  韩锁成(2);  郭景春(3);  范薇(1)
收藏  |  浏览/下载：3/0  |  提交时间：2019/12/19

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