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Dezocine as a potent analgesic: overview of its pharmacological characterization 期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 12
作者:  Ye, Rong-Rong;  Jiang, Shuang;  Xu, Xu;  Lu, Yan;  Wang, Yu-Jun
收藏  |  浏览/下载:30/0  |  提交时间:2021/12/16
Novel selective kappa agonists SLL-039 and SLL-1206 produce potent antinociception with fewer sedation and aversion 期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 11
作者:  Wei, Yuan-yuan;  Ma, Yan;  Yao, Song-yu;  Kong, Ling-hui;  Liu, Xiao
收藏  |  浏览/下载:40/0  |  提交时间:2021/11/04
Discovery of an M-Substituted N-Cyclopropylmethyl-7 alpha-phenyl-6,14-endoethanotetrahydronorthebaine as a Selective, Potent, and Orally Active kappa-Opioid Receptor Agonist with an Improved Central Nervous System Safety Profile 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 16, 页码: 12414-12433
作者:  He, Qian;  Wei, Yuanyuan;  Liu, Xiao;  Ye, Rongrong;  Kong, Linghui
收藏  |  浏览/下载:88/0  |  提交时间:2021/11/04
Discovery, Structure-Activity Relationship, and Mechanistic Studies of 1-((3R,4S)-3-((Dimethylamino)methyl)-4-hydroxy-4-(3-methoxyphenyl)piperidin-1-yl)-2-(2,4,5-trifluorophenyl)ethan-1-one as a Novel Potent Analgesic 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 13, 页码: 9458-9483
作者:  Huang, Huoming;  Li, Xueping;  Xie, Peng;  Li, Xinwei;  Xu, XueJun
收藏  |  浏览/下载:29/0  |  提交时间:2021/08/17
Neurobiological Bases of Social Networks 期刊论文
FRONTIERS IN PSYCHOLOGY, 2021, 卷号: 12, 页码: 17
作者:  Han, Mengfei;  Jiang, Gaofang;  Luo, Haoshuang;  Shao, Yongcong
收藏  |  浏览/下载:81/0  |  提交时间:2021/06/09
The Distinct Functions of Dopaminergic Receptors on Pain Modulation: A Narrative Review 期刊论文
NEURAL PLASTICITY, 2021, 卷号: 2021, 页码: 11
作者:  Wang, Xia-qing;  Mokhtari, Tahmineh;  Zeng, Yu-xuan;  Yue, Lu-peng;  Hu, Li
收藏  |  浏览/下载:23/0  |  提交时间:2021/04/30
Design, Synthesis, and Structure-Activity Relationship Exploration of Alkyl/Phenylalkyl Piperidine Analogues as Novel Highly Potent and Selective mu Opioid Receptor Agonists 期刊论文
ACS CHEMICAL NEUROSCIENCE, 2021, 卷号: 12, 期号: 2, 页码: 285-299
作者:  Huang, Huoming;  Li, Xinwei;  Guo, Wei;  Zhu, Chen;  Qian, Yuanyuan
收藏  |  浏览/下载:26/0  |  提交时间:2021/05/24
Molecular mechanisms of fentanyl mediated beta-arrestin biased signaling 期刊论文
PLOS COMPUTATIONAL BIOLOGY, 2020, 卷号: 16, 期号: 4, 页码: 24
作者:  de Waal, Parker W.;  Shi, Jingjing;  You, Erli;  Wang, Xiaoxi;  Melcher, Karsten
收藏  |  浏览/下载:27/0  |  提交时间:2020/07/01
Discovery of 3-((dimethylamino)methyl)-4-hydroxy-4-(3-methoxypheny1)-N-phenylpiperidine-1-carboxamide as novel potent analgesic 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 189, 页码: 14
作者:  Huang, Huoming;  Wang, Wenli;  Xu, Xuejun;  Zhu, Chen;  Wang, Yujun
收藏  |  浏览/下载:33/0  |  提交时间:2020/07/01
Discovery of a Highly Selective and Potent kappa Opioid Receptor Agonist from N-Cyclopropylmethyl-7 alpha-phenyl-6,14-endoethanotetrahydronorthebaines with Reduced Central Nervous System (CNS) Side Effects Navigated by the Message-Address Concept 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 24, 页码: 11054-11070
作者:  Xiao, Li;  Wang, Yujun;  Zhang, Mumei;  Wu, Weiwei;  Kong, Linghui
收藏  |  浏览/下载:92/0  |  提交时间:2020/07/01


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