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上海药物研究所 [9]
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DW14383 is an irreversible pan-FGFR inhibitor that suppresses FGFR-dependent tumor growth in vitro and in vivo
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 9
作者:
Dai, Meng-di
;
Wang, Yue-liang
;
Fan, Jun
;
Dai, Yang
;
Ji, Yin-chun
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2021/05/24
receptor tyrosine kinase
FGFR inhibitor
DW14383
antitumor activity
Pyrazolo[4,3-b]pyrimido[4,5-e][1,4]diazepine derivatives as new multi-targeted inhibitors of Aurora A/B and KDR
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 158, 页码: 428-441
作者:
Zhang, Qiumeng
;
Shen, Qianqian
;
Gao, Lixin
;
Tong, Linjiang
;
Li, Jia
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2019/01/08
Aurora A
Aurora B
KDR
Multi-targeted
Anticancer
Heterocyclic
慈济化癌保生方对肝癌H22荷瘤小鼠化疗后微血管密度及病理血管生成因子的影响
学位论文
2017, 2016
赵心悦
收藏
  |  
浏览/下载:132/0
  |  
提交时间:2017/06/20
慈济化癌保生方
肿瘤血管生成
微血管密度(MVD)
VEGF
KDR
bFGF
Ciji Hua’ai Baosheng Formula (CHBF)
tumor angiogenesis
microvessel density (MVD)
vascular endothelial growth factor (VEGF)
kinase insert domain-containing receptor (KDR)
basic fibroblast growth factor (bFGF)
Discovery of novel Ponatinib analogues for reducing KDR activity as potent FGFRs inhibitors
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 126, 页码: 122-132
作者:
Liu, Yang
;
Peng, Xia
;
Guan, Xiaocong
;
Lu, Dong
;
Xi, Yong
收藏
  |  
浏览/下载:42/0
  |  
提交时间:2019/01/08
FGFR
KDR
Inhibitor
Anticancer
Ponatinib
Genetic Variants of VEGF (rs201963 and rs3025039) and KDR (rs7667298, rs2305948, and rs1870377) Are Associated with Glioma Risk in a Han Chinese Population: a Case-Control Study
期刊论文
MOLECULAR NEUROBIOLOGY, 2016, 卷号: 53, 期号: 4
作者:
Zhang, Jiannan
;
Yang, Jian
;
Chen, Yuqing
;
Mao, Qin
;
Li, Shanquan
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2019/12/13
Glioma
Vascular endothelial growth factor
Kinase insert domain receptor
Single nucleotide polymorphism
Han Chinese population
Genetic markers
One type of VEGFR is involved in WSSV infection to the Pacific whiteleg shrimp Litopenaeus vannamei
期刊论文
DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY, 2015, 卷号: 50, 期号: 1, 页码: 1-8
作者:
Li, Shihao
;
Wang, Zhiwei
;
Li, Fuhua
;
Xiang, Jianhai
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2015/06/15
VEGFR
WSSV
RNA interference
Litopenaeus vannamei
Chemical Constituents from the Heartwood of Haematoxylon campechianum as Protein Tyrosine Kinase Inhibitors
期刊论文
CHEMISTRY & BIODIVERSITY, 2014, 卷号: 11, 期号: 5, 页码: 776-783
作者:
Lin, Li-Gen
;
Xie, Hua
;
Wang, Yi-Tao
;
Ding, Jian
;
Ye, Yang
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2019/01/08
Haematoxylon campechianum
Protein tyrosine kinases (PTKs)
Epihematoxylol B
Homoisoflavonoids
Hematoxylol B
10-O-methyl-
Kinase insert domain receptor (KDR)
Expression of Soluble Vascular Endothelial Growth Factor Receptor-2 and Its Effect on Proliferation of Vascular Endothelial Cells
期刊论文
CHEMICAL RESEARCH IN CHINESE UNIVERSITIES, 2012, 卷号: 28, 期号: 2
作者:
Wang Song
;
Lu Jian-nan
;
Xu Yan
;
Liu Lu-cheng
;
Wu Jiang
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2019/12/05
Kinase insert domain-containing receptor(KDR)
Angiogenesis
Human umbilical vein endothelial cell (HUVEC)
Chick chorioallantoic membrane(CAM)
Expression of Soluble Vascular Endothelial Growth Factor Receptor-2 and Its Effect on Proliferation of Vascular Endothelial Cells
期刊论文
CHEMICAL RESEARCH IN CHINESE UNIVERSITIES, 2012, 卷号: 28, 期号: 2
作者:
Wang Song
;
Lu Jian-nan
;
Xu Yan
;
Liu Lu-cheng
;
Wu Jiang
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2019/12/05
Kinase insert domain-containing receptor(KDR)
Angiogenesis
Human umbilical vein endothelial cell (HUVEC)
Chick chorioallantoic membrane(CAM)
OSI-930 analogues as novel reversal agents for ABCG2-mediated multidrug resistance
期刊论文
Biochemical Pharmacology, 2012, 卷号: 84, 期号: 6, 页码: 766-774
作者:
Ye-Hong Kuang
;
Jay P. Patel
;
Kamlesh Sodani
;
Chung-Pu Wu
;
Li-Qiu Liao
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2019/12/03
OSI-930
{N-(4-trifluoromethoxyphenyl)3-((quinolin-4-ylmethyl) amino) thiophene-2-carboxamide}
ABC
ATP binding cassette
ABCG2 (BCRP/MXR/ABCP)
ABC subfamily G member 2
MDR
multidrug resistance
P-gp
P-glycoprotein
ABCCs (MRPs)
ABC subfamily C member
RTK
receptor tyrosine kinases
KDR
kinase insert domain receptor
TKIs
tyrosine kinase inhibitors
IAAP
[125I]-iodoarylazidoprazosin
FTC
fumitremorgin C
MTT
3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide
DMSO
dimethylsulfoxide
OSI-930
ABC transporters
ABCG2
Multidrug resistance
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