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CORC

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JC-010a, a novel selective SHP2 allosteric inhibitor, overcomes RTK/non-RTK-mediated drug resistance in multiple oncogene-addicted cancers 期刊论文
CANCER LETTERS, 2024, 卷号: 582, 页码: 15
作者:  Lu, Xuxiu;  Yu, Rilei;  Li, Zhen;  Yang, Mengke;  Dai, Jiajia
收藏  |  浏览/下载：4/0  |  提交时间：2024/04/07
Impact of clinical and molecular features on efficacy and outcome of patients with non-small cell lung cancer receiving second-line osimertinib 期刊论文
BMC CANCER, 2022, 卷号: 22
作者:  Jin, Ying;  Lin, Chen;  Shi, Xun;  He, Qiong;  Yan, Junrong
收藏  |  浏览/下载：21/0  |  提交时间：2022/12/23
Clinical outcomes of lung adenocarcinoma patients harboring uncommon epidermal growth factor receptor (EGFR) mutations treated with EGFR-tyrosine kinase inhibitors (TKIs) 期刊论文
ANNALS OF PALLIATIVE MEDICINE, 2021
作者:  Si, Jinfei;  Gu, Xiaodong;  Wang, Wenxian;  Ying, Shenpeng;  Song, Zhengbo
收藏  |  浏览/下载：59/0  |  提交时间：2022/02/14
LS-106, a novel EGFR inhibitor targeting C797S, exhibits antitumor activities both in vitro and in vivo 期刊论文
CANCER SCIENCE, 2021, 页码: 12
作者:  Liu, Yingqiang;  Lai, Mengzhen;  Li, Shan;  Wang, Yanan;  Feng, Fang
收藏  |  浏览/下载：62/0  |  提交时间：2022/01/18
Discovery of Cyclic Peptidomimetic Ligands Targeting the Extracellular Domain of EGFR 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 15, 页码: 11219-11228
作者:  Zheng, Mengmeng;  Li, Chunpu;  Zhou, Mi;  Jia, Ru;  Cai, Gang
收藏  |  浏览/下载：65/0  |  提交时间：2021/11/04
The correlation between the abundance of EGFR T790M mutation and osimertinib response in advanced non-small cell lung cancer 期刊论文
TRANSLATIONAL CANCER RESEARCH, 2021, 卷号: 10
作者:  Pan, Guoqiang;  Chen, Kaiyan;  Yu, Xiaoqing;  Sheng, Jiamin;  Fan, Yun
收藏  |  浏览/下载：38/0  |  提交时间：2021/11/01
The genomic landscape of young and old lung cancer patients highlights age-dependent mutation frequencies and clinical actionability in young patients 期刊论文
INTERNATIONAL JOURNAL OF CANCER, 2021
作者:  Cai, Lei;  Chen, Yong;  Tong, Xiaoling;  Wu, Xue;  Bao, Hua
收藏  |  浏览/下载：63/0  |  提交时间：2021/06/15
Drug interaction of ningetinib and gefitinib involving CYP1A1 and efflux transporters in non-small cell lung cancer patients 期刊论文
BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 2020, 页码: 13
作者:  Liu, Lu;  Wang, Qian;  Xie, Cen;  Xi, Ning;  Guo, Zitao
收藏  |  浏览/下载：55/0  |  提交时间：2020/12/24
Design, synthesis and biological evaluation of potent EGFR kinase inhibitors against 19D/T790M/C797S mutation 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2020, 卷号: 30, 期号: 16, 页码: 6
作者:  Su, Zhicheng;  Yang, Tingyuan;  Wang, Jie;  Lai, Mengzhen;  Tong, Linjiang
收藏  |  浏览/下载：27/0  |  提交时间：2020/12/24
EGFR  NSCLC  C797S  
Targeting Hsp90 with FS-108 circumvents gefitinib resistance in EGFR mutant non-small cell lung cancer cells (vol 37, pg 1587, 2020) 期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 2
作者:  Wang, Yue-qin;  Shen, Ai-jun;  Sun, Jing-ya;  Wang, Xin;  Liu, Hong-chun
收藏  |  浏览/下载：12/0  |  提交时间：2020/07/01

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