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期刊论文 [29]
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Design, synthesis, in vitro evaluation of a new pyrrolo[1,2-a]thiazolo[5,4-d]pyrimidinone derivatives as cholinesterase inhibitors against Alzheimer's disease
期刊论文
JOURNAL OF HETEROCYCLIC CHEMISTRY, 2022, 卷号: 59, 期号: 6, 页码: 1086-1101
作者:
Zeng, Y (Zeng, Yan) [1] , [2]
;
Nie, LF (Nie, Lifei) [1]
;
Liu, L (Liu, Liu) [1]
;
Niu, C (Niu, Chao) [1] , [2]
;
Li, Y (Li, Yi) [1] , [2]
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2022/06/21
Twin drug design, synthesis and evaluation of diosgenin derivatives as multitargeted agents for the treatment of vascular dementia
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2021, 卷号: 37, 页码: 16
作者:
Yang, Gui-Xiang
;
Sun, Jia-Min
;
Zheng, Lu-Lu
;
Zhang, Li
;
Li, Jie
收藏
  |  
浏览/下载:71/0
  |  
提交时间:2021/06/11
Vascular dementia
Diosgenin
Antioxidant
Anti-cholinesterase
Multi-target-directed ligands
Rational Design of Novel Selective Dual-Target Inhibitors of Acetylcholinesterase and Monoamine Oxidase B as Potential Anti-Alzheimer's Disease Agents
期刊论文
ACS chemical neuroscience, 2018
作者:
Xu, Yixiang
;
Zhang, Jian
;
Wang, Huan
;
Mao, Fei
;
Bao, Keting
收藏
  |  
浏览/下载:85/0
  |  
提交时间:2019/01/08
Cholinesterases and engineered mutants for the detection of organophosphorus pesticide residues (Open Access)
期刊论文
Sensors (Switzerland), 2018, 卷号: 18, 期号: 12
作者:
Xu, Yu-Ling
;
Li, Feng-Ye
;
Ndikuryayo, Ferdinand
;
Yang, Wen-Chao*
;
Wang, Hong-Mei*
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2019/12/23
cholinesterase
mutant
organophosphorus pesticides
sensor
Cholinesterases and engineered mutants for the detection of organophosphorus pesticide residues (Open Access)
期刊论文
Sensors (Switzerland), 2018, 卷号: 18, 期号: 12
作者:
Xu, Yu-Ling
;
Li, Feng-Ye
;
Ndikuryayo, Ferdinand
;
Yang, Wen-Chao*
;
Wang, Hong-Mei*
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/27
cholinesterase
mutant
organophosphorus pesticides
sensor
Gorge Motions of Acetylcholinesterase Revealed by Microsecond Molecular Dynamics Simulations
期刊论文
SCIENTIFIC REPORTS, 2017, 卷号: 7
作者:
Cheng, Shanmei
;
Song, Wanling
;
Yuan, Xiaojing
;
Xu, Yechun
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2019/01/08
Fabrication of Propeller-Shaped Supra-amphiphile for Construction of Enzyme-Responsive Fluorescent Vesicles
期刊论文
ACS APPLIED MATERIALS & INTERFACES, 2016
Li, Jie
;
Liu, Kaerdun
;
Han, Yuchun
;
Tang, Ben Zhong
;
Huang, Jianbin
;
Yan, Yun
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2017/12/03
enzyme-responsive
ATE
fluorescent-vesicle
self-assembly
supra-amphiphile
AGGREGATION-INDUCED EMISSION
MOLECULAR-STRUCTURES
ALZHEIMERS-DISEASE
AIE LUMINOGEN
TETRAPHENYLETHENE
ASSEMBLIES
SYSTEMS
NANOPARTICLES
MICROTUBES
CHEMISTRY
Fabrication of Propeller-Shaped Supra-amphiphile for Construction of Enzyme-Responsive Fluorescent Vesicles
期刊论文
ACS applied materials & interfaces, 2016
Li Jie
;
Liu Kaerdun
;
Han Yuchun
;
Tang Ben Zhong
;
Huang Jianbin
;
Yan Yun
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2017/12/04
AIE,enzyme-responsive,fluorescent vesicle,self-assembly,supra-amphiphile
(-)-Meptazinol-melatonin hybrids as novel dual inhibitors of cholinesterases and amyloid-beta aggregation with high antioxidant potency for Alzheimer's therapy
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2015, 卷号: 23, 期号: 13
作者:
Cheng, Shaobing
;
Zheng, Wei
;
Gong, Ping
;
Zhou, Qiang
;
Xie, Qiong
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2019/12/05
Alzheimer's disease
Multi-target-directed ligands
A beta aggregation
Antioxidant
(-)-Meptazinol-melatonin hybrids as novel dual inhibitors of cholinesterases and amyloid-beta aggregation with high antioxidant potency for Alzheimer's therapy
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2015, 卷号: 23, 期号: 13
作者:
Cheng, Shaobing
;
Zheng, Wei
;
Gong, Ping
;
Zhou, Qiang
;
Xie, Qiong
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/19
Alzheimer's disease
Multi-target-directed ligands
A beta aggregation
Antioxidant
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