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上海药物研究所 [19]
复旦大学上海医学院 [15]
山东大学 [10]
过程工程研究所 [9]
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浏览/检索结果:
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Ameliorating Ribosylation-Induced Amyloid-beta Pathology by Berberine via Inhibiting mTOR/p70S6K Signaling
期刊论文
JOURNAL OF ALZHEIMERS DISEASE, 2021, 卷号: 79, 期号: 2, 页码: 833-844
作者:
Wang, Yang-Yang
;
Yan, Qian
;
Huang, Zhen-Ting
;
Zou, Qian
;
Li, Jing
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2021/03/29
AGEs
Alzheimer's disease
amyloid-beta
autophagy
berberine
mTOR
DW14006 as a direct AMPK alpha 1 activator improves pathology of AD model mice by regulating microglial phagocytosis and neuroinflammation
期刊论文
BRAIN BEHAVIOR AND IMMUNITY, 2020, 卷号: 90, 页码: 55-69
作者:
Lv, Jianlu
;
Wang, Wei
;
Zhu, Xialin
;
Xu, Xiaoju
;
Yan, Qiuying
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2020/12/21
Alzheimer'sdisease
Microglia
AMPK alpha 1
DW14006
Phagocytosis
Neuro-inflammation
Blood-Brain Barrier Permeable Chitosan Oligosaccharides Interfere with beta-Amyloid Aggregation and Alleviate beta-Amyloid Protein Mediated Neurotoxicity and Neuroinflammation in a Dose- and Degree of Polymerization-Dependent Manner
期刊论文
MARINE DRUGS, 2020, 卷号: 18, 期号: 10, 页码: 22
作者:
Zhu, Limeng
;
Li, Ruilian
;
Jiao, Siming
;
Wei, Jinhua
;
Yan, Yalu
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2021/03/29
Alzheimer’
s disease
chitosan oligosaccharides
blood-brain barrier
Aβ
42
aggregation
binding affinity
cytotoxicity
Vaccines targeting the primary amino acid sequence and conformational epitope of amyloid-beta had distinct effects on neuropathology and cognitive deficits in EAE/AD mice
期刊论文
BRITISH JOURNAL OF PHARMACOLOGY, 2020, 页码: 12
作者:
Yu, Xiao-Lin
;
Zhu, Jie
;
Liu, Xiang-meng
;
Xu, Peng-xin
;
Zhang, Yue
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  |  
浏览/下载:6/0
  |  
提交时间:2020/05/21
Neuroprotective Effects of Triterpenoids from Camellia japonica against Amyloid β-Induced Neuronal Damage
期刊论文
Journal of Natural Products, 2020, 卷号: 83, 期号: 7, 页码: 2076–2086
作者:
Hyo-Moon Cho
;
Thi-Kim-Quy Ha
;
Thi-Phuong Doan
;
Basanta Dhodary
;
Jin-Pyo An
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2020/11/16
Four new cembranoids from the Chinese soft coral Sinularia sp. and their anti-A beta aggregation activities
期刊论文
FITOTERAPIA, 2019, 卷号: 136, 页码: 6
作者:
Jiang, Cheng-Shi
;
Ru, Tong
;
Yao, Li-Gong
;
Miao, Ze-Hong
;
Guo, Yue-Wei
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  |  
浏览/下载:16/0
  |  
提交时间:2020/07/01
Soft coral
Sinularia sp.
Cembranoids
Diterpenoid
Amyloid-beta (A beta) aggregation
Molecular docking
Protective effects of tanshinone IIA on SH-SY5Y cells against oAβ1-42-induced apoptosis due to prevention of endoplasmic reticulum stress.
期刊论文
The international journal of biochemistry & cell biology, 2019, 卷号: 107, 页码: 82-91
作者:
Yang Weina
;
Zhang Jianshui
;
Shi Lili
;
Ji Shengfeng
;
Yang Xiaohua
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2019/11/19
Tanshinone IIA
Apoptosis
Endoplasmic reticulum stress
Alzheimer disease
&beta
-amyloid protein
Fe3+ Facilitates Endocytic Internalization of Extracellular A beta(1-42) and Enhances A beta(1-42)-Induced Caspase-3/Caspase-4 Activation and Neuronal Cell Death
期刊论文
MOLECULAR NEUROBIOLOGY, 2019, 卷号: 56, 期号: 7
作者:
Nishizaki, Tomoyuki
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2019/12/05
Amyloid beta(1-42)
Fe3+
Internalization
Endocytosis
Neuronal cell death
Caspase activation
Jia-Wei-Kai-Xin-San, an Herbal Medicine Formula, Ameliorates Cognitive Deficits via Modulating Metabolism of Beta Amyloid Protein and Neurotrophic Factors in Hippocampus of A beta(1-42 )Induced Cognitive Deficit Mice
期刊论文
FRONTIERS IN PHARMACOLOGY, 2019, 卷号: 10
作者:
Zhu, Yue
;
Shi, Yiwei
;
Cao, Cheng
;
Han, Zhenxiang
;
Liu, Mengqiu
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2019/12/05
Alzheimer's disease
beta amyloid protein
neurotrophic factor
Jia-Wei-Kai-Xin-San
Chinese medicine formula
Transcriptomics and proteomics analysis of A (1-42)-induced neurotoxicity
期刊论文
MOLECULAR & CELLULAR TOXICOLOGY, 2019, 卷号: 15, 期号: 3
作者:
Qin, Zhenxia
;
Su, Zhonghao
;
Dong, Zhuo
;
Guo, Chunxia
;
Xu, Ying
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2019/12/05
beta-Amyloid peptide
Neurotoxicity
Neuroblastoma cells
Microarray
PF-2D
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