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Inhibiting NLRP3 inflammasome activation prevents copper-induced neuropathology in a murine model of Wilson's disease 期刊论文
CELL DEATH & DISEASE, 2021, 卷号: 12
作者:  Dong, Jianjian;  Wang, Xun;  Xu, Chenchen;  Gao, Manli;  Wang, Shijing
收藏  |  浏览/下载:122/0  |  提交时间:2021/03/15
The artemisinin analog SM934 alleviates dry eye disease in rodent models by regulating TLR4/NF-kappa B/NLRP3 signaling 期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 11
作者:  Yang, Fang-ming;  Fan, Di;  Yang, Xiao-qian;  Zhu, Feng-hua;  Shao, Mei-juan
收藏  |  浏览/下载:26/0  |  提交时间:2020/12/24
Subventricular zone-derived extracellular vesicles promote functional recovery in rat model of spinal cord injury by inhibition of NLRP3 inflammasome complex formation 期刊论文
METABOLIC BRAIN DISEASE, 2020, 页码: 10
作者:  Mohammed, Ibrahim;  Ijaz, Sahar;  Mokhtari, Tahmineh;  Gholaminejhad, Morteza;  Mahdavipour, Marzieh
收藏  |  浏览/下载:27/0  |  提交时间:2020/05/18
IMM-H004 therapy for permanent focal ischemic cerebral injury via CKLF1/CCR4-mediated NLRP3 inflammasome activation 期刊论文
2019, 卷号: 212, 页码: 36-53
作者:  Ai Q D;  Chen Chen;  Chu Shifeng;  Zhang Zhao;  Luo Yun
收藏  |  浏览/下载:26/0  |  提交时间:2020/01/03
ASC = apoptosis-associated speck-like protein containing a caspase activation recruitment domain  BCA = bicinchoninic acid  BSA = bovine serum albumin  CCA = common carotid artery  CCR4 = C-C chemokine receptor type 4  CKLF1 = chemokine-like factor 1  CO-IP = coimmunoprecipitation  ECA = external carotid artery  ELISA = enzyme-linked immunosorbent assay  FDA = Food and Drug Administration  I/R = ischemic/reperfusion  ICA = internal carotid artery  IL-18 = interleukin 18  IL-1β = interleukin 1β  LDH = lactate dehydrogenase  NLRP3 = NOD-like receptor protein 3  PBS = phosphate-buffered saline  SD = standard deviation  TNF-α = tumor necrosis factor α  TTC = 2  3  5-triphenyltetrazolium-chloride  WT = wild-type  pMCAO = permanent middle cerebral artery occlusion  pro-Caspase-1 = precursor Caspase-1  qPCR = quantitative real-time PCR  tMCAO = transient middle cerebral artery occlusion  tPA = tissue plasminogen activator  
Coptisine from Coptis chinensis blocks NLRP3 inflammasome activation by inhibiting caspase-1 期刊论文
PHARMACOLOGICAL RESEARCH, 2019, 卷号: 147, 页码: 104348
作者:  Wu, Jiasi;  Luo, Yu;  Jiang, Qing;  Li, Sheng;  Huang, Wenge
收藏  |  浏览/下载:17/0  |  提交时间:2021/11/10
Interleukin-enhanced binding factor 2 interacts with NLRP3 to inhibit the NLRP3 inflammasome activation 期刊论文
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2018, 卷号: 500, 期号: 2
作者:  Jin, Jing;  Li, Aixin;  Wang, Wenbiao;  Wu, Jianguo
收藏  |  浏览/下载:5/0  |  提交时间:2019/12/05
Early-life lipopolysaccharide exposure potentiates forebrain expression of NLRP3 inflammasome proteins and anxiety-like behavior in adolescent rats 期刊论文
Brain Research, 2017, 卷号: 1671, 期号: Volume 1671, 页码: 43-54
作者:  Lei, Yuan;  Chen, Chu-Jun;  Yan, Xiao-Xin;  Li, Zhiyuan;  Deng, Xiao-Hua*
收藏  |  浏览/下载:11/0  |  提交时间:2019/12/03
Mlkl and fadd are critical for suppressing progressive lymphoproliferative disease and activating the nlrp3 inflammasome 期刊论文
Cell reports, 2016, 卷号: 16, 期号: 12, 页码: 3247-3259
作者:  Zhang, Xixi;  Fan, Cunxian;  Zhang, Haiwei;  Zhao, Qun;  Liu, Yongbo
收藏  |  浏览/下载:39/0  |  提交时间:2019/05/09
Defective Intestinal Mucin-Type O-Glycosylation Causes Spontaneous Colitis-Associated Cancer in Mice 期刊论文
Gastroenterology, 2016, 卷号: 151, 期号: 1, 页码: 152-164.e11
作者:  Bergstrom, Kirk;  Liu, Xiaowei;  Zhao, Yiming;  Gao, Nan;  Wu, Qian
收藏  |  浏览/下载:2/0  |  提交时间:2019/12/03
Magnesium lithospermate B acts against dextran sodiumsulfate-induced ulcerative colitis by inhibiting activation of the NRLP3/ASC/Caspase-1 pathway 期刊论文
ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY, 2016, 卷号: 41
作者:  Jiang, Xiaoyun;  Zhong, Liang;  Sun, Dayu;  Rong, Lan
收藏  |  浏览/下载:6/0  |  提交时间:2019/12/06


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