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Design, synthesis and biological evaluation of pyrazolo[3,4-d]pyridazinone derivatives as covalent FGFR inhibitors 期刊论文
ACTA PHARMACEUTICA SINICA B, 2021, 卷号: 11, 期号: 3, 页码: 781-794
作者:  Wu, Xiaowei;  Dai, Mengdi;  Cui, Rongrong;  Wang, Yulan;  Li, Chunpu
收藏  |  浏览/下载:47/0  |  提交时间:2021/05/24
Glycogen synthase kinase 3 beta inhibition synergizes with PARP inhibitors through the induction of homologous recombination deficiency in colorectal cancer 期刊论文
CELL DEATH & DISEASE, 2021, 卷号: 12, 期号: 2, 页码: 18
作者:  Zhang, Ning;  Tian, Yu-Nan;  Zhou, Li-Na;  Li, Meng-Zhu;  Chen, Hua-Dong
收藏  |  浏览/下载:21/0  |  提交时间:2021/05/24
A Pharmacodynamic Evaluation Method Based on Optogenetics and Graphene FETs 会议论文
Jiaxing, China, July 27-31, 2021
作者:  Yang J(杨佳);  Zu LP(祖立鹏);  Dang D(党丹);  Li MY(李梦月);  Wang WX(王文学)
收藏  |  浏览/下载:13/0  |  提交时间:2021/11/27
USP28 and USP25 are downregulated by Vismodegib in vitro and in colorectal cancer cell lines 期刊论文
FEBS JOURNAL, 2020, 页码: 18
作者:  Wang, Hui;  Meng, Qian;  Ding, Yiluan;  Xiong, Muya;  Zhu, Mengying
收藏  |  浏览/下载:84/0  |  提交时间:2020/12/24
Structure‐based pharmacophore models to probe anticancer activity of inhibitors of protein kinase B‐beta (PKB β). 期刊论文
Chemical Biology & Drug Design, 2019, 卷号: Vol.93 No.3, 页码: 325-336
作者:  Akhtar, N.a;  Jabeen, I.a;  Jalal, N.b;  Antilla, J.b
收藏  |  浏览/下载:16/0  |  提交时间:2019/11/21
Identification of novel and potent small-molecule inhibitors of tubulin with antitumor activities by virtual screening and biological evaluations 期刊论文
JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN, 2019, 卷号: 33, 期号: 7, 页码: 659-664
作者:  Liu, Guangpu;  Jiao, Yang;  Huang, Chunxi;  Chang, Ping
收藏  |  浏览/下载:4/0  |  提交时间:2019/12/11
Screening DNA-targeted anticancer drug in vitro based on cancer cells DNA-templated silver nanoclusters 期刊论文
SCIENTIFIC REPORTS, 2019, 卷号: 9, 期号: 1
作者:  Zhang, Feng;  Sheng, Hao*;  Wang, Shuang;  Ma, Yu;  Cai, Changqun*
收藏  |  浏览/下载:3/0  |  提交时间:2019/12/23
Reynoutria Japonica from Traditional Chinese Medicine: A Source of Competitive Adenosine Deaminase Inhibitors for Anticancer 期刊论文
COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING, 2019, 卷号: 22, 期号: 2, 页码: 113-122
作者:  Zhang, Xin-Guo;  Ma, Guo-Yan;  Fei Kou;  Liu, Wen-Jie;  Sun, Qiao-Yun
收藏  |  浏览/下载:5/0  |  提交时间:2019/11/15
High-throughput screening campaigns against a PI3K alpha isoform bearing the H1047R mutation identified potential inhibitors with novel scaffolds 期刊论文
ACTA PHARMACOLOGICA SINICA, 2018, 卷号: 39, 期号: 11, 页码: 1816-1822
作者:  Wang, Jia;  Gong, Grace Qun;  Zhou, Yan;  Lee, Woo-Jeong;  Buchanan, Christina Maree
收藏  |  浏览/下载:84/0  |  提交时间:2019/01/08
Synthesis, biological evaluation and structure-activity relationship of a novel class of PI3K alpha H1047R mutant inhibitors 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 158, 页码: 707-719
作者:  Zhang, Ning;  Yu, Zhimei;  Yang, Xiaohong;  Zhou, Yan;  Wang, Jia
收藏  |  浏览/下载:85/0  |  提交时间:2019/01/08


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