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上海药物研究所 [9]
复旦大学上海医学院 [2]
中国医学科学院 北京... [2]
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武汉大学 [1]
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期刊论文 [16]
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浏览/检索结果:
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The deep learning model combining CT image and clinicopathological information for predicting ALK fusion status and response to ALK-TKI therapy in non-small cell lung cancer patients
期刊论文
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, 2020
作者:
Song, Zhengbo
;
Liu, Tianchi
;
Shi, Lei
;
Yu, Zongyang
;
Shen, Qing
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2020/10/26
Deep learning model
Anaplastic lymphoma kinase
Computed tomography
Non-small cell lung cancer
CT-Based Radiomic Signature as a Prognostic Factor in Stage IV ALK-Positive Non-small-cell Lung Cancer Treated With TKI Crizotinib: A Proof-of-Concept Study
期刊论文
FRONTIERS IN ONCOLOGY, 2020, 卷号: 10, 页码: 9
作者:
Li, Hailin
;
Zhang, Rui
;
Wang, Siwen
;
Fang, Mengjie
;
Zhu, Yongbei
收藏
  |  
浏览/下载:48/0
  |  
提交时间:2020/04/07
computed tomography
radiomics
non-small-cell lung cancer
tyrosine kinase inhibitor resistance
anaplastic lymphoma kinase
Chinese perspectives on clinical efficacy and safety of alectinib in patients with ALK-positive advanced non-small cell lung cancer
期刊论文
ONCOTARGETS AND THERAPY, 2019, 卷号: 12
作者:
Yu, Hui
;
Sun, Si
;
Hu, Xingjiang
;
Xia, Jinjing
;
Wang, Jialei
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2019/12/05
NSCLC
anaplastic lymphoma kinase
alectinib
tyrosine kinase inhibitor
ALK-G1269A mutation in epithelioid inflammatory myofibroblastic sarcoma after progression on crizotinib: A case report
期刊论文
ONCOLOGY LETTERS, 2019, 卷号: 17, 期号: 2
作者:
Xu, Xiaojing
;
Li, Hong
;
Peng, Ke
;
Yu, Yiyi
;
Chen, Lingli
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2019/12/05
epithelioid inflammatory myofibroblastic sarcoma
anaplastic lymphoma kinase
kinase inhibitor
crizotinib
Brigatinib
drug resistance
Treatment Optimization for Brain Metastasis from Anaplastic Lymphoma Kinase Rearrangement Non-Small-Cell Lung Cancer
期刊论文
2019, 页码: 1-8
作者:
Wang Wenhui
;
Sun Xin
;
Hui Zhouguang
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2020/01/03
Anaplastic lymphoma kinase
Brain metastasis
Non-small-cell lung cancer
Radiation therapy
Tyrosine kinase inhibitor
Treatment duration as a surrogate endpoint to evaluate the efficacy of crizotinib in sequential therapy for patients with advanced ALK-positive non-small cell lung cancer: A retrospective, real-world study
期刊论文
2019, 卷号: 8, 期号: 13, 页码: 5823-5830
作者:
Yang Guangjian
;
Ma Di
;
Xu Haiyan
;
Yang Lu
;
Li Junling
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2020/01/03
anaplastic lymphoma kinase inhibitor
crizotinib
crizotinib continuation beyond progressive disease
non-small cell lung cancer
treatment duration
Design, synthesis and pharmacological evaluation of ALK and Hsp90 dual inhibitors bearing resorcinol and 2,4-diaminopyrimidine motifs
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 152, 页码: 76-86
作者:
Geng, Kaijun
;
Liu, Hongchun
;
Song, Zilan
;
Zhang, Chi
;
Zhang, Minmin
收藏
  |  
浏览/下载:177/0
  |  
提交时间:2019/01/08
Heat shock protein 90 (Hsp90)
Tyrosine kinase ALK
Dual inhibitor
Drug resistance
Antiproliferative activity
Discovery of 2,4-diarylaminopyrimidines bearing a resorcinol motif as novel ALK inhibitors to overcome the G1202R resistant mutation
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 144, 页码: 386-397
作者:
Geng, Kaijun
;
Xia, Zongjun
;
Ji, Yinchun
;
Zhang, Ruisi (Ruthy)
;
Sun, Deqiao
收藏
  |  
浏览/下载:155/0
  |  
提交时间:2019/01/08
ALK
G1202R mutant
Drug resistance
2,4-Diarylaminopyrimidine
Resorcinol
Pharmacologic characterization of CT-711, a novel dual inhibitor of ALK and c-Met
期刊论文
AMERICAN JOURNAL OF CANCER RESEARCH, 2018, 卷号: 8, 期号: 8, 页码: 1541-1550
作者:
Wang, Lei
;
Gao, Mingzhao
;
Tong, Mengya
;
Xie, Chengying
;
He, Ye
收藏
  |  
浏览/下载:151/0
  |  
提交时间:2019/01/08
CT-711
ALK
c-Met
crizotinib
antitumor activity
pharmacokinetics
Mutation L1196M-induced conformational changes and the drug resistant mechanism of anaplastic lymphoma kinase studied by free energy perturbation and umbrella sampling
期刊论文
PHYSICAL CHEMISTRY CHEMICAL PHYSICS, 2017, 卷号: 19, 期号: 44, 页码: 30239-30248
作者:
Chen, Jianzhong
;
Wang, Jinan
;
Zhu, Weiliang
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2019/01/08
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