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上海神经科学研究所 [5]
上海药物研究所 [4]
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Sanguinarine is an agonist of TRPA1 channel
期刊论文
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2021, 卷号: 534, 页码: 226-232
作者:
Chi, Hao
;
Zhang, Xian
;
Chen, Xueqin
;
Fang, Sui
;
Ding, Qiang
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2021/05/24
Sanguinarine
Alkaloid
TRPA1
Agonist
Pain
Structure-Based Discovery of a Subtype-Selective Inhibitor Targeting a Transient Receptor Potential Vanilloid Channel
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 3, 页码: 1373-1384
作者:
Chai, Hao
;
Cheng, Xi
;
Zhou, Bin
;
Zhao, Lifen
;
Lin, Xianhua
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2020/07/01
Transient receptor potential vanilloid-type 2 targeting on stemness in liver cancer
期刊论文
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2018, 卷号: 105, 页码: 697-706
作者:
Hu, Zecheng
;
Cao, Xiaocheng
;
Fang, Yu
;
Liu, Guoxing
;
Xie, Chengzhi
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2019/12/27
HHC
Human Hepatocellular Carcinoma
LCSLC
sliver cancer stem-like cells
TRPV2
Transient Receptor Potential Vanilloid-type 2 channel
TRP
Transient Receptor Potential
SCID
severe combined immunodeficiency
ALDH1
aldehyde dehydrogenase 1
GFP
green fluorescent protein
LPL
lysophospholipids
CAPE
caffeic acid phenethyl ester
hrbFGF
human recombinant basic fibroblast growth factor
hrEGF
human recombinant epidermal growth factor
TRPC
Transient Receptor Potential Canonical
TRPM
Transient Receptor Potential Melastatin
TRPV
Transient Receptor Potential Vanilloid
JNK1
c-jun N-terminal kinase-1
MRP
multidrug-resistant protein
ABCC2
ATP-binding cassette subfamily C member 2
MRP4
Multidrug Resistance Protein 4
CSC
Cancer Stem Cell
DMEM
Dulbecco modified Eagle medium
Liver cancer
Liver cancer stem cell
Transient receptor potential vanilloid-type 2 channel
Probenecid
Tranilast
Self-renewal
Transient receptor potential vanilloid-type 2 targeting on stemness in liver cancer
期刊论文
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2018, 卷号: 105, 页码: 697-706
作者:
Hu, Zecheng
;
Cao, Xiaocheng
;
Fang, Yu
;
Liu, Guoxing
;
Xie, Chengzhi
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2019/12/27
HHC
Human Hepatocellular Carcinoma
LCSLC
sliver cancer stem-like cells
TRPV2
Transient Receptor Potential Vanilloid-type 2 channel
TRP
Transient Receptor Potential
SCID
severe combined immunodeficiency
ALDH1
aldehyde dehydrogenase 1
GFP
green fluorescent protein
LPL
lysophospholipids
CAPE
caffeic acid phenethyl ester
hrbFGF
human recombinant basic fibroblast growth factor
hrEGF
human recombinant epidermal growth factor
TRPC
Transient Receptor Potential Canonical
TRPM
Transient Receptor Potential Melastatin
TRPV
Transient Receptor Potential Vanilloid
JNK1
c-jun N-terminal kinase-1
MRP
multidrug-resistant protein
ABCC2
ATP-binding cassette subfamily C member 2
MRP4
Multidrug Resistance Protein 4
CSC
Cancer Stem Cell
DMEM
Dulbecco modified Eagle medium
Liver cancer
Liver cancer stem cell
Transient receptor potential vanilloid-type 2 channel
Probenecid
Tranilast
Self-renewal
TRPA1 channel mediates organophosphate-induced delayed neuropathy
期刊论文
CELL DISCOVERY, 2017, 卷号: 3
作者:
Ding, Qiang
;
Fang, Sui
;
Chen, Xueqin
;
Wang, Youxin
;
Li, Jian
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2019/01/08
organophosphate
malathion
TOCP
OPIDN
TRPA1
Pyrazolopyrimidines as Potent Stimulators for Transient Receptor Potential Canonical 3/6/7 Channels
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 60, 期号: 11, 页码: 4680-4692
作者:
Qu, Chunrong
;
Ding, Mingmin
;
Zhu, Yingmin
;
Lu, Yungang
;
Du, Juan
收藏
  |  
浏览/下载:89/0
  |  
提交时间:2019/01/08
Pyrazolopyrimidines as Potent Stimulators for Transient Receptor Potential Canonical 3/6/7 Channels.
期刊论文
2017, 卷号: Vol.60 No.11, 页码: 4680-4692
作者:
Chunrong Qu
;
Mingmin Ding
;
Yingmin Zhu
;
Yungang Lu
;
Juan Du
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2019/04/16
PYRIMIDINES
TRP
channels
ADRENERGIC
agonists
GLOMERULOSCLEROSIS
CELLULAR
signal
transduction
THERAPEUTIC
use
Selective Activation of Nociceptor TRPV1 Channel and Reversal of Inflammatory Pain in Mice by a Novel Coumarin Derivative Muralatin L from Murraya alata
期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2016, 卷号: 192, 期号: 2, 页码: 640-651
作者:
Wei NN
;
Lv HN
;
Wu Y
;
Yang SL
;
Sun XY
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2016/03/04
calcium
calcium imaging
drug discovery
drug screening
ion channel
neuron
transient receptor potential channels (TRP channels)
醋酸铅对人和小鼠瞬时受体电位A1离子通道的抑制作用
期刊论文
中国药理学与毒理学杂志, 2016, 卷号: 30, 期号: 9, 页码: 949-954
作者:
赵红
;
宋玉竹[*]
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2016/12/01
醋酸铅
背根神经节
神经元
瞬时受体电位A1通道
电压钳技术
钙成像
Transient Receptor Potential Channel and Interleukin-17A Involvement in LTTL Gel Inhibition of Bone Cancer Pain in a Rat Model
期刊论文
INTEGRATIVE CANCER THERAPIES, 2015, 卷号: 14, 期号: 4
作者:
Wang, Juyong
;
Zhang, Ruixin
;
Dong, Changsheng
;
Jiao, Lijing
;
Xu, Ling
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2019/12/05
herbs
cancer pain
TRP channels
IL-17A
spinal cord
dorsal root ganglia
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