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科研机构
上海药物研究所 [4]
中国医学科学院 北京... [2]
中南大学 [1]
吉林大学白求恩第一医... [1]
复旦大学上海医学院 [1]
内容类型
期刊论文 [9]
发表日期
2021 [1]
2018 [2]
2017 [2]
2016 [1]
2014 [1]
2013 [1]
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Discovery of pyrrolo[2,3-d]pyrimidine derivatives as potent Axl inhibitors: Design, synthesis and biological evaluation
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 220, 页码: 18
作者:
Xu, Dandan
;
Sun, Deqiao
;
Wang, Wei
;
Peng, Xia
;
Zhan, Zhengsheng
收藏
  |  
浏览/下载:47/0
  |  
提交时间:2021/08/17
Axl
Cancer
Inhibitor
Pyrrolo[2,3-d]pyrimidine
Dual-targeting biomimetic delivery for anti-glioma activity via remodeling the tumor microenvironment and directing macrophagemediated immunotherapy
期刊论文
CHEMICAL SCIENCE, 2018, 卷号: 9, 期号: 10, 页码: 2674-2689
作者:
Zhao, Pengfei
;
Wang, Yonghui
;
Kang, Xuejia
;
Wu, Aihua
;
Yin, Weimin
收藏
  |  
浏览/下载:39/0
  |  
提交时间:2019/01/08
Age-related changes in expression and signaling of TAM receptor inflammatory regulators in monocytes.
期刊论文
Oncotarget, 2018, 卷号: 9, 期号: 11
作者:
Wang Xiaomei
;
Malawista Anna
;
Qian Feng
;
Ramsey Christine
;
Allore Heather G
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2019/12/05
5 immunosenescence
Gerotarget
TAM receptors
age-related immune dysregulation
monocyte
protein S
Reprogramming Tumor-Associated Macrophages To Reverse EGFR(T790M) Resistance by Dual-Targeting Codelivery of Gefitinib/Vorinostat
期刊论文
NANO LETTERS, 2017, 卷号: 17, 期号: 12, 页码: 7684-7690
作者:
Peng, Huige
;
Chen, Binfan
;
Huang, Wei
;
Tang, Yubo
;
Jiang, Yifan
收藏
  |  
浏览/下载:66/0
  |  
提交时间:2019/01/08
Tumor-associated macrophages
gefitinib
vorinostat
EGFR(T790M)
nonsmall cell lung cancer
drug resistance
Combination of metformin with chemotherapeutic drugs via different molecular mechanisms
期刊论文
Cancer Treatment Reviews, 2017, 卷号: 54, 页码: 24-33
作者:
Peng, Mei*
;
Darko, Kwame Oteng
;
Tao, Ting
;
Huang, Yanjun
;
Su, Qiongli
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2019/12/03
AIs
aromatase inhibitors
AMPK
Adenosine Monophosphate-Activated Protein Kinase
AR
androgen
ATM
Ataxia Telangiectasia Mutated
ATP
Adenosine Triphosphate
BCSS
breast cancer specific survival
CK-MB
Creatine Kinase-MB
CREB1
cAMP Response Element-Binding Protein 1
CSC
cancer stem cell
DFS
disease-free survival
DHFU
dihydrofluorouracil
DPD
dihydropyrimidine dehydrogenase
EpCAM
Epithelial Cell Adhesion Molecule
ER
estrogen
ERCC1
excision repair cross-complementary 1
ERK
extracellular signal-regulated kinases
EZH2
enhancer of zeste homolog 2
FdUMP
fluorodeoxyuridine monophosphate
FdUTP
fluorodeoxyuridine triphosphate
FHC
ferritin heavy chain
FUTP
fluorouridine triphosphate
HbA1C
hemoglobin A1c
HER
Human Epidermal Growth Factor Receptor
HIF-1α
hypoxia-inducible factor-1α
HK
hexokinase
IGF1R
insulin growth factor 1 receptor
LDH
lactate dehydrogenase
MDA
Muscular Dystrophy Association
MMP
Matrix Metallopeptidase
MRP1
multidrug resistance-associated protein 1
mTOR
mammalian target of rapamycin
MTX
methotrexate
NCCN
National Comprehensive Cancer Network
OS
overall survival
pCR
Pathologic Complete Response
PDGFR
platelet-derived growth factor receptors
PFS
progression-free survival
PKA
protein kinase A
PR
progesterone receptor
RFS
relapse-free survival
SOD
superoxide dismutase
TAM
tamoxifen
TCA
tricarboxlic acid
TS
thymidylate synthase
Combination
Mechanisms
Metformin
Chemotherapeutic drugs
Staphylococcus aureus Leukocidin LukED and HIV-1 gp120 Target Different Sequence Determinants on CCR5
期刊论文
MBIO, 2016, 卷号: 7, 期号: 6
作者:
Tam, Kayan
;
Schultz, Megan
;
Reyes-Robles, Tamara
;
Vanwalscappel, Benedicte
;
Horton, Joshua
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2019/01/08
TAM Receptors Support Neural Stem Cell Survival, Proliferation and Neuronal Differentiation
期刊论文
PLOS ONE, 2014, 卷号: 9, 期号: 12
作者:
Ji, Rui
;
Meng, Lingbin
;
Jiang, Xin
;
Kumar, Naresh C. V. M.
;
Ding, Jixiang
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2019/12/05
Breakdown of immune homeostasis in the testis of mice lacking Tyro3, Axl and Mer receptor tyrosine kinases
期刊论文
2013, 卷号: 91, 期号: 6, 页码: 416-426
作者:
Zhang, Yue
;
Li, Nan
;
Chen, Qiaoyuan
;
Yan, Keqin
;
Liu, Zhenghui
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2020/01/13
immune homeostasis
inflammation
TAM receptors
testis
Toll-like receptor-mediated inhibition of Gas6 and ProS expression facilitates inflammatory cytokine production in mouse macrophages
期刊论文
2012, 卷号: 135, 期号: 1, 页码: 40-50
作者:
Deng, Tingting
;
Zhang, Yue
;
Chen, Qiaoyuan
;
Yan, Keqin
;
Han, Daishu
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2020/01/13
Gas6
inflammation
protein S
TAM receptors
toll-like receptor
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