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科研机构
上海药物研究所 [5]
西藏大学 [2]
西安交通大学 [1]
天津大学 [1]
内容类型
期刊论文 [9]
发表日期
2019 [1]
2018 [3]
2015 [2]
2014 [1]
2013 [2]
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Urea and thiourea derivatives of 3--5,6,7,8-tetrahydro-[1, 2, 4]triazolo[4,3-a]pyrazine: Synthesis, characterization, antimicrobial activity and docking studies.
期刊论文
Phosphorus, Sulfur & Silicon & the Related Elements, 2019, 卷号: Vol.194 No.9, 页码: 922-932
作者:
Mannam, Madhava Rao
;
Devineni, Subba Rao
;
Pavuluri, Chandra Mouli
;
Chamarthi, Naga Raju
;
Kottapalli, Raja Sekhara P
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2019/11/21
adenosine-5-diphosphoribose enzyme
antimicrobial activity
molecular docking
sitagliptin intermediate
structural characterization
Urea and thiourea derivatives
Synthesis, nitric oxide release, and dipeptidyl peptidase-4 inhibition of sitagliptin derivatives as new multifunctional antidiabetic agents.
期刊论文
Bioorganic & medicinal chemistry letters, 2018, 卷号: 28, 页码: 3731-3735
作者:
Xie Yundong
;
Shao Lihua
;
Wang Qiutang
;
Bai Yue
;
Chen Zizhang
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2019/11/26
Anti-platelet aggregation
Antioxidant
Dipeptidyl peptidase IV
Hypoglycemic
Nitric oxide
Sitagliptin derivatives
Synthesis, nitric oxide release, and dipeptidyl peptidase-4 inhibition of sitagliptin derivatives as new multifunctional antidiabetic agents.
期刊论文
2018
作者:
Xie Yundong
;
Shao Lihua
;
Wang Qiutang
;
Bai Yue
;
Chen Zizhang
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2019/04/15
Anti-platelet
aggregation
Antioxidant
Dipeptidyl
peptidase
IV
Hypoglycemic
Nitric
oxide
Sitagliptin
derivatives
Synthesis, nitric oxide release, and dipeptidyl peptidase-4 inhibition of sitagliptin derivatives as new multifunctional antidiabetic agents
期刊论文
2018
作者:
Yundong Xie
;
Lihua Shao
;
Qiutang Wang
;
Yue Bai
;
Zizhang Chen
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2019/04/15
Nitric
oxide
Dipeptidyl
peptidase
IV
Hypoglycemic
Antioxidant
Anti-platelet
aggregation
Sitagliptin
derivatives
Design, Synthesis, and Pharmacological Evaluation of Highly Potent and Selective Dipeptidyl Peptidase-4 Inhibitors
期刊论文
ARCHIV DER PHARMAZIE, 2015, 卷号: 348, 期号: 6, 页码: 399-407
作者:
Jiang, Tao
;
Zhou, Yuren
;
Zhu, Jianming
;
Chen, Zhuxi
;
Sun, Peng
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2019/01/08
beta-Homophenylalanine
DPP-4
Drug design
Inhibitors
P2-binding moiety
Design, Synthesis, and Pharmacological Evaluation of Fused beta-Homophenylalanine Derivatives as Potent DPP-4 Inhibitors
期刊论文
ACS MEDICINAL CHEMISTRY LETTERS, 2015, 卷号: 6, 期号: 5, 页码: 602-606
作者:
Jiang, Tao
;
Zhou, Yuren
;
Chen, Zhuxi
;
Sun, Peng
;
Zhu, Jianming
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2019/01/08
Diabetes
DPP-4 inhibitor
beta-homophenylalanine derivatives
sitagliptin
(R)-3-Amino-1-((3aS,7aS)-octahydro-1H-indol-1-yl)-4-(2,4,5-trifluorophenyl)butan-1-one derivatives as potent inhibitors of dipeptidyl peptidase-4: Design, synthesis, biological evaluation, and molecular modeling
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2014, 卷号: 22, 期号: 23, 页码: 6684-6693
作者:
Wang, Sinan
;
Su, Mingbo
;
Wang, Jiang
;
Li, Zeng
;
Zhang, Lei
收藏
  |  
浏览/下载:108/0
  |  
提交时间:2019/01/08
DPP-4
Type 2 diabetes
Inhibitor
Binding mode
Oral bioavailability
Synthesis and biological evaluation of novel benzyl-substituted (S)-phenylalanine derivatives as potent dipeptidyl peptidase 4 inhibitors
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2013, 卷号: 21, 期号: 18, 页码: 5679-5687
作者:
Liu, Yang
;
Si, Meimei
;
Tang, Li
;
Shangguan, Shihao
;
Wu, Haoshu
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2019/01/08
Dipeptidyl peptidase 4 inhibitors
Type 2 diabetes
1,2,3-Triazole
(S)-Phenylalanine derivatives
Selectivity
Design and Synthesis of 4-(2,4,5-Trifluorophenyl)butane-1,3-diamines as Dipeptidyl PeptidaseIV Inhibitors
期刊论文
CHEMMEDCHEM, 2013, 卷号: 8, 期号: 7, 页码: 1104-1116
作者:
Zhu, Linrong
;
Li, Yuanyuan
;
Qiu, Ling
;
Su, Mingbo
;
Wang, Xin
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2019/01/08
1
3-diamines
crystal structures
dipeptidyl peptidaseIV
inhibitors
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