CORC

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CORC

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Peptidic microarchitecture-trapped tumor vaccine combined with immune checkpoint inhibitor or PI3K gamma inhibitor can enhance immunogenicity and eradicate tumors 期刊论文
JOURNAL FOR IMMUNOTHERAPY OF CANCER, 2022, 卷号: 10, 期号: 2, 页码: 13
作者:  Du, Yang;  Liu, Ye;  Wang, Di;  Bai, Hua;  Wang, Zhijie
收藏  |  浏览/下载：25/0  |  提交时间：2022/06/06
Repressing MYC by targeting BET synergizes with selective inhibition of PI3K alpha against B cell lymphoma 期刊论文
CANCER LETTERS, 2022, 卷号: 524, 页码: 206-218
作者:  Chen, Zi-qi;  Cao, Zhe-rui;  Wang, Yi;  Zhang, Xi
收藏  |  浏览/下载：53/0  |  提交时间：2021/12/16
CYH33  MYC  P300  BET  B cell lymphoma  PI3K  
Synthesis and bioactivity studies of covalent inhibitors derived from (-)-Chaetominine 期刊论文
JOURNAL OF MOLECULAR STRUCTURE, 2021, 卷号: 1241, 页码: 14
作者:  Zhou, Xian;  Feng, Xuexin;  Wang, Dachi;  Chen, Deheng;  Wu, Gaoxing
收藏  |  浏览/下载：83/0  |  提交时间：2021/08/17
PI3K alpha inhibitor CYH33 triggers antitumor immunity in murine breast cancer by activating CD8(+)T cells and promoting fatty acid metabolism 期刊论文
JOURNAL FOR IMMUNOTHERAPY OF CANCER, 2021, 卷号: 9, 期号: 8, 页码: 16
作者:  Sun, Pu;  Zhang, Xi;  Wang, Rong-Jing;  Ma, Qing-Yang;  Xu, Lan
收藏  |  浏览/下载：42/0  |  提交时间：2021/11/04
The dual HDAC-PI3K inhibitor CUDC-907 displays single-agent activity and synergizes with PARP inhibitor olaparib in small cell lung cancer 期刊论文
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH, 2020, 卷号: 39
作者:  Ma, Liying;  Bian, Xing;  Lin, Wenchu
收藏  |  浏览/下载：38/0  |  提交时间：2020/11/30
Nitidine chloride exerts anti-inflammatory action by targeting Topoisomerase I and enhancing IL-10 production 期刊论文
2019, 卷号: 148, 页码: 104368
作者:  Yang Niao;  Yue Rongcai;  Ma Jinzhu;  Li Wencai;  Zhao Zeng
收藏  |  浏览/下载：39/0  |  提交时间：2020/01/03
High-throughput screening campaigns against a PI3K alpha isoform bearing the H1047R mutation identified potential inhibitors with novel scaffolds 期刊论文
ACTA PHARMACOLOGICA SINICA, 2018, 卷号: 39, 期号: 11, 页码: 1816-1822
作者:  Wang, Jia;  Gong, Grace Qun;  Zhou, Yan;  Lee, Woo-Jeong;  Buchanan, Christina Maree
收藏  |  浏览/下载：84/0  |  提交时间：2019/01/08
Synthesis, biological evaluation and structure-activity relationship of a novel class of PI3K alpha H1047R mutant inhibitors 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 158, 页码: 707-719
作者:  Zhang, Ning;  Yu, Zhimei;  Yang, Xiaohong;  Zhou, Yan;  Wang, Jia
收藏  |  浏览/下载：84/0  |  提交时间：2019/01/08
Difuran-substituted quinoxalines as a novel class of PI3K alpha H1047R mutant inhibitors: Synthesis, biological evaluation and structure activity relationship 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 157, 页码: 37-49
作者:  Zhang, Ning;  Yu, Zhimei;  Yang, Xiaohong;  Zhou, Yan;  Tang, Qing
收藏  |  浏览/下载：25/0  |  提交时间：2019/01/08
Serum and glucocorticoid inducible protein kinases (SGKs): a potential target for cancer intervention 期刊论文
ACTA PHARMACEUTICA SINICA B, 2018, 卷号: 8, 期号: 5, 页码: 767-771
作者:  Basnet, Rajesh;  Gong, Grace Qun;  Li, Chenyao;  Wang, Ming-Wei
收藏  |  浏览/下载：30/0  |  提交时间：2019/01/08

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