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CORC

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Cryo-EM structures of PI3K alpha reveal conformational changes during inhibition and activation 期刊论文
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2021, 卷号: 118, 期号: 45, 页码: 9
作者:  Liu, Xiao;  Yang, Su;  Hart, Jonathan R.;  Xu, Yingna;  Zou, Xinyu
收藏  |  浏览/下载：39/0  |  提交时间：2022/01/04
X-box binding protein l splicing attenuates brain microvascular endothelial cell damage induced by oxygen-glucose deprivation through the activation of phosphoinositide 3-kinase/protein kinase B, extracellular signal-regulated kinases, and hypoxia-inducible factor-1 alpha/vascular endothelial growth factor signaling pathways 期刊论文
JOURNAL OF CELLULAR PHYSIOLOGY, 2019, 卷号: 234, 期号: 6
作者:  Shi, Shupeng;  Tang, Mimi;  Li, Honglei;  Ding, Hui;  Lu, Yangfan
收藏  |  浏览/下载：40/0  |  提交时间：2019/12/04
Immunostimulatory Effects of Chitooligosaccharides on RAW 264.7 Mouse Macrophages via Regulation of the MAPK and PI3K/Akt Signaling Pathways 期刊论文
MARINE DRUGS, 2019, 卷号: 17, 期号: 1, 页码: 12
作者:  Yang, Yue;  Xing, Ronge;  Liu, Song;  Qin, Yukun;  Li, Kecheng
收藏  |  浏览/下载：75/0  |  提交时间：2019/08/28
Design, Synthesis, and Biological Evaluation of 4-Methyl Quinazoline Derivatives as Anticancer Agents Simultaneously Targeting Phosphoinositide 3-Kinases and Histone Deacetylases 期刊论文
2019, 卷号: 62, 期号: 15, 页码: 6992-7014
作者:  Zhang, Kehui;  Lai, Fangfang;  Lin, Songwen;  Ji, Ming;  Zhang, Jingbo
收藏  |  浏览/下载：3/0  |  提交时间：2020/01/03
Global Phosphoproteomic Analysis Reveals the Defense and Response Mechanisms of Jatropha Curcas Seedling under Chilling Stress 期刊论文
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2019, 卷号: 20, 期号: 1
作者:  Liu, Hui;  Wang, Fen-Fen;  Peng, Xian-Jun;  Huang, Jian-Hui;  Shen, Shi-Hua
收藏  |  浏览/下载：20/0  |  提交时间：2022/01/06
A phosphatidylinositol 4,5-bisphosphate redistribution-based sensing mechanism initiates a phagocytosis programing 期刊论文
NATURE COMMUNICATIONS, 2018, 卷号: 9, 页码: 16
作者:  Mu, Libing;  Tu, Zhongyuan;  Miao, Lin;  Ruan, Hefei;  Kang, Ning
收藏  |  浏览/下载：91/0  |  提交时间：2018/12/04
Synthesis, biological evaluation and structure-activity relationship of a novel class of PI3K alpha H1047R mutant inhibitors 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 158, 页码: 707-719
作者:  Zhang, Ning;  Yu, Zhimei;  Yang, Xiaohong;  Zhou, Yan;  Wang, Jia
收藏  |  浏览/下载：85/0  |  提交时间：2019/01/08
Serum and glucocorticoid inducible protein kinases (SGKs): a potential target for cancer intervention 期刊论文
ACTA PHARMACEUTICA SINICA B, 2018, 卷号: 8, 期号: 5, 页码: 767-771
作者:  Basnet, Rajesh;  Gong, Grace Qun;  Li, Chenyao;  Wang, Ming-Wei
收藏  |  浏览/下载：30/0  |  提交时间：2019/01/08
Discovery of (S)-2-amino-N-(5-(6-chloro-5-(3-methylphenylsulfonamido)pyridin-3-yl)-4-methylthiazol-2-yl)-3-methylbutanamide (CHMFL-PI3KD-317) as a potent and selective phosphoinositide 3-kinase delta (PI3K delta) inhibitor 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 156, 页码: 831-846
作者:  Liang, Xiaofei;  Li, Feng;  Chen, Cheng;  Jiang, Zongru;  Wang, Aoli
收藏  |  浏览/下载：13/0  |  提交时间：2019/12/10
Survivin-targeting miR-542-3p overcomes HER3 signaling-induced chemoresistance and enhances the antitumor activity of paclitaxel against HER2-overexpressing breast cancer 期刊论文
Cancer Letters, 2018, 卷号: 420, 页码: 97-108
作者:  Lyu, Hui;  Wang, Shuiliang;  Huang, Jingcao;  Wang, Bolun;  He, Zhimin
收藏  |  浏览/下载：8/0  |  提交时间：2019/12/03

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