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CORC

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The Novel RET Inhibitor SYHA1815 Inhibits RET-Driven Cancers and Overcomes Gatekeeper Mutations by Inducing G1 Cell-Cycle Arrest through c-Myc Downregulation 期刊论文
MOLECULAR CANCER THERAPEUTICS, 2021, 卷号: 20, 期号: 11, 页码: 2198-2206
作者:  Jiang, Yuchen;  Peng, Xia;  Ji, Yinchun;  Dai, Yang;  Fang, Yanfen
收藏  |  浏览/下载：29/0  |  提交时间：2021/12/16
Synthesis and biological evaluation of 2,5-diaryl-1,3,4-oxadiazole derivatives as novel Src homology 2 domain-containing protein tyrosine phosphatase 2 (SHP2) inhibitors 期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 116, 页码: 13
作者:  Meng, Xiang-Dong;  Gao, Li-Xin;  Wang, Zhi-Jia;  Feng, Bo;  Zhang, Chun
收藏  |  浏览/下载：31/0  |  提交时间：2021/12/01
Transcriptome Regulation by Oncogenic ALK Pathway in Mammalian Cortical Development Revealed by Single-Cell RNA Sequencing 期刊论文
CEREBRAL CORTEX, 2021, 卷号: 31, 期号: 8, 页码: 3911-3924
作者:  Mao, Rui;  Zhang, Xiaoyun;  Kong, Youyong;  Wu, Shanshan;  Huo, Hai-qin
收藏  |  浏览/下载：34/0  |  提交时间：2021/08/17
Discovery of thalidomide-based PROTAC small molecules as the highly efficient SHP2 degraders 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 218, 页码: 14
作者:  Yang, Xiangbo;  Wang, Zhijia;  Pei, Yuan;  Song, Ning;  Xu, Lei
收藏  |  浏览/下载：40/0  |  提交时间：2021/08/17
Whole-exome mutational landscape of neuroendocrine carcinomas of the gallbladder 期刊论文
SIGNAL TRANSDUCTION AND TARGETED THERAPY, 2021, 卷号: 6
作者:  Liu, Fatao;  Li, Yongsheng;  Ying, Dongjian;  Qiu, Shimei;  He, Yong
收藏  |  浏览/下载：27/0  |  提交时间：2021/04/26
Dual functions of SPOP and ERG dictate androgen therapy responses in prostate cancer 期刊论文
NATURE COMMUNICATIONS, 2021, 卷号: 12, 期号: 1, 页码: 18
作者:  Bernasocchi, Tiziano;  El Tekle, Geniver;  Bolis, Marco;  Mutti, Azzurra;  Vallerga, Arianna
收藏  |  浏览/下载：22/0  |  提交时间：2021/05/24
A Peptide Binder of E3 Ligase Adaptor SPOP Disrupts Oncogenic SPOP-Protein Interactions in Kidney Cancer Cells 期刊论文
CHINESE JOURNAL OF CHEMISTRY, 2020, 页码: 274-280
作者:  Wang, Zhen;  Zhang, Hao;  Chen, Baoen;  Ouyang, Sisheng;  Zheng, Tong
收藏  |  浏览/下载：124/0  |  提交时间：2021/05/24
Progress on treatment of MET signaling pathway in non-small cell lung cancer 期刊论文
INTERNATIONAL JOURNAL OF CLINICAL ONCOLOGY, 2020
作者:  Yu, Xiaoqing;  Yu, Sizhe;  Fan, Yun
收藏  |  浏览/下载：24/0  |  提交时间：2020/11/26
EPHA2 feedback activation limits the response to PDE delta inhibition in KRAS-dependent cancer cells 期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 卷号: 41, 期号: 2, 页码: 270-277
作者:  Chen, Yue-hong;  Lv, Hao;  Shen, Ning;  Wang, Xiao-min;  Tang, Shuai
收藏  |  浏览/下载：33/0  |  提交时间：2020/07/01
Distinct co-acquired alterations and genomic evolution during TKI treatment in non-small-cell lung cancer patients with or without acquired T790M mutation 期刊论文
ONCOGENE, 2020, 卷号: 39
作者:  Jin, Ying;  Bao, Hua;  Le, Xiuning;  Fan, Xiaojun;  Tang, Ming
收藏  |  浏览/下载：25/0  |  提交时间：2020/11/26

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