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Metformin, beyond an insulin sensitizer, targeting heart and pancreatic β cells 期刊论文
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 2017, 卷号: 1863, 期号: 8, 页码: 1984-1990
作者:  Yang, Xin;  Xu, Zhipeng;  Zhang, Chunlan;  Cai, Zixin;  Zhang, Jingjing*
收藏  |  浏览/下载:37/0  |  提交时间:2019/12/03
A1c  glycated hemoglobin  AACE  American Association of Clinical Endocrinologists  ACC  acetyl-CoA carboxylase  ADA  American Diabetes Association  Akt/PKB  tyrosine kinase/protein kinase B  AMP  adenosine monophosphate  AMPK  adenosine monophosphate-activated protein  Ang II  angiotensin II  ATP  adenosine triphosphate  BAT  brown adipose tissue  CHOP  CEBP-homologous protein  CEBP  CCAAT enhancer binding protein  CoA  coenzyme A  DPP  Diabetes Prevention Program  EASD  European Association for the Study of Diabetes  eNOS  endothelial nitric oxide synthase  ER  endoplasmic reticulum  FDA  Food and Drug Administration  FFA  free fatty acid  FOXO1  forkhead box protein O1  G6P  glucose 6-phosphate  GDM  gestational diabetes mellitus  GIPR  glucose-dependent insulinotropic polypeptide receptor  GLP-1R  glucagon-like peptide-1 receptor  GLUT1  glucose transporter-1  GLUT4  glucose transporter type 4  GLUTs  glucose transporters  G6P  glucose 6-phosphate, glucose transporter-1  GPR40  G protein-coupled receptor 40  HbA1c  hemoglobin A1c  HGP  hepatic glucose production  HSL  hormone sensitive lipase  IL-6  interleukin 6  INS-1  insulinoma cells in rat  IR  insulin resistance  IRS-1  insulin receptor substrate 1  JNK  c-Jun. N-terminal kinase  Kir6.2  inwardly rectifying potassium/kalium channel  LDs  lipid droplets  LDL  low density lipoprotein  LV  left ventricular  MIN6 cells  mouse insulinoma cells  MAPK  mitogen-activated protein kinases  mPTP  mitochondrial permeability transition pore opening  mTOR  mammalian target of rapamycin  NADPH  nicotinamide adenine dinucleotide phosphate  NF-kappaB  nuclear factors-kappa B  NIT-1 cells  insulinoma cells  p70S6K  p70 ribosomal S6 kinase  PA  palmitic acid  NOS  NADPH oxidase  p38 MAPK  p38 mitogen-activated protein kinase  PA  palmitic acid  PCOS  polycystic ovary syndrome  PGC-1α  peroxisome proliferator-activated receptor-g coactivator-1α  PI3K  phosphatidylinositol 3-kinase  PKB  protein kinase B  PKC  protein kinase C  PPARα  peroxisome-proliferator activated receptor α  PTP  permeability transition pore  RCT  randomized controlled trial  RISK  reperfusion injury salvage kinase  ROS  reactive oxygen species  SERCA2  reticulum sarcoplasmic Ca2 +-ATPase  RISK  reperfusion injury salvage kinase  Smad3  mothers against decapentaplegic homolog 3  SRC-2  steroid receptor coactivator 2  T1DM  Type 1 diabetes mellitus  T2DM  Type 2 diabetes mellitus  TGFβ1  transforming growth factor β1  TLR4  Toll-like receptor  TNF-α  tumor necrosis factor α  TR4  testicular receptor 4  UKPDS  United Kingdom Prospective Diabetes Study  VLDL  very low density lipoprotein  Metformin  Pancreatic β Cells  Heart failure  Insulin sensitizer  
分泌型磷脂酶PLA2G12B和PLA2G2E参与调节肝脏和巨噬细胞脂质转运的研究 学位论文
广州生物院: 中国科学院研究生院, 2015
作者:  瞿林兵
收藏  |  浏览/下载:166/0  |  提交时间:2018/12/24
I. 转录共激活子PGC-1α与丙型肝炎病毒相互作用研究 II. 丙型肝炎病毒Vero细胞培养系统建立初步研究 学位论文
广州生物院: 中国科学院研究生院, 2014
作者:  蔡华
收藏  |  浏览/下载:20/0  |  提交时间:2018/12/24
Cloning and characterization of a novel apolipoprotein gene, apolipoprotein AV, in tree shrews 期刊论文
MOLECULAR BIOLOGY REPORTS, 2013, 卷号: 40, 期号: 9, 页码: 5429-5438
作者:  Li, Guoping;  Luo, Huairong;  Sun, Guotao;  Wu, Guisheng;  Wu, Gang
收藏  |  浏览/下载:19/0  |  提交时间:2013/10/16
基于核磁共振代谢组学对2型糖尿病合并脑梗死的研究 期刊论文
2013
马红; 王雅静; 董继扬; 杨香玖; 黄延玲
收藏  |  浏览/下载:6/0  |  提交时间:2016/05/17
Comparison of serum metabolite compositions between obese and lean growing pigs using an NMR-based metabonomic approach 期刊论文
JOURNAL OF NUTRITIONAL BIOCHEMISTRY, 2012, 卷号: 23, 期号: 2, 页码: 133-139
作者:  He, Qinghua;  Ren, Pingping;  Kong, Xiangfeng;  Wu, Yongning;  Wu, Guoyao
收藏  |  浏览/下载:30/0  |  提交时间:2015/06/25
Effects of dietary Astragalus polysaccharide and Astragalus membranaceus root supplementation on growth performance, rumen fermentation, immune responses, and antioxidant status of lambs 期刊论文
Animal Feed Science and Technology, 2012, 卷号: 174, 期号: 1-2, 页码: 60-67
作者:  Zhong, R. Z.;  Yu, M.;  Liu, H. W.;  Sun, H. X.;  Cao, Y.
收藏  |  浏览/下载:11/0  |  提交时间:2019/12/23
ADFom  ash-free acid detergent fiber  ADG  average daily gain  AMT  Astragalus membranaceus root  aNDFom  amylase-treated ash-free neutral detergent fiber  APS  Astragalus polysaccharide  BUN  blood urea N  BW  body weight  CAT  catalase  CP  crude protein  DM  dry matter  FE  feed efficiency  GPx  glutathione peroxidase  HDLC  high density lipoprotein cholesterol  Ig  immunoglobulin  LDLC  low density lipoprotein cholesterol  VLDL  very low density lipoprotein  ME  metabolisable energy  TAC  total antioxidant capacity  T-SOD  total superoxide dismutase  VFA  volatile fatty acid  Astragalus membranaceus root  Astragalus polysaccharide  Rumen fermentation  Antioxidant  Immune responses  Weaned lambs  
冷空气活动对人群血脂水平的影响 期刊论文
环境与健康杂志, 2011, 期号: 11, 页码: 953-955
作者:  赵娜娟;  牛静萍;  阮烨;  张莉;  张秉玲
收藏  |  浏览/下载:5/0  |  提交时间:2016/09/05
NMR-based Metabonomics Study on Serum and Urine of Hyperthyroidism 期刊论文
2010
Wei, Y. Y.; Wang, C. H.; Li, W.; Dong, J. Y.; Chen, Z.; 董继扬
收藏  |  浏览/下载:2/0  |  提交时间:2013/12/12
NMR-based Metabonomics Study on Serum and Urine of Hyperthyroidism 期刊论文
2010
Wei, Y. Y.; Wang, C. H.; Li, W.; Dong, J. Y.; Chen, Z.; 陈忠
收藏  |  浏览/下载:2/0  |  提交时间:2013/12/12


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