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上海药物研究所 [9]
北京大学 [7]
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期刊论文 [31]
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Novel selective kappa agonists SLL-039 and SLL-1206 produce potent antinociception with fewer sedation and aversion
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 11
作者:
Wei, Yuan-yuan
;
Ma, Yan
;
Yao, Song-yu
;
Kong, Ling-hui
;
Liu, Xiao
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2021/11/04
kappa-opioid receptor agonist
4,5-expoxymorphinan
antinociception
conditioned place aversion
sedation
U50,488H
morphine
Nor-BNI
beta-FNA
Clinical opioids differentially induce co-internalization of mu- and delta-opioid receptors
期刊论文
MOLECULAR PAIN, 2018, 卷号: 14, 期号: 1, 页码: 1-15
作者:
Bao, Fenghua
;
Li, Chang-Lin
;
Lu, Ying-Jin
;
Zhang, Xu
;
Chen, Xu-Qiao
收藏
  |  
浏览/下载:42/0
  |  
提交时间:2019/04/28
Protein-coupled Receptors
Knock-out Mice
Morphine Antinociceptive Tolerance
Dorsal-root Ganglia
Opiate Tolerance
Beta-arrestin
Desensitization
Trafficking
Dependence
Analgesia
Spinal TRPC6 channels contributes to morphine-induced antinociceptive tolerance and hyperalgesia in rats
期刊论文
NEUROSCIENCE LETTERS, 2017, 卷号: 639
作者:
Jin, Hua
;
Sun, Ying-tong
;
Guo, Guang-qiong
;
Chen, Da-lin
;
Li, Yu-jin
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/04
TRPC6
Morphine
Tolerance
Hyperalgesia
Opioid receptor trafficking and interaction in nociceptors
期刊论文
BRITISH JOURNAL OF PHARMACOLOGY, 2015, 卷号: 172, 期号: 2, 页码: 364-374
作者:
Zhang, X.
;
Bao, L.
;
Li, S.
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  |  
浏览/下载:17/0
  |  
提交时间:2015/04/22
DORSAL-ROOT GANGLIA
PROTEIN-COUPLED RECEPTORS
DENSE-CORE VESICLES
SUBSTANCE-P RELEASE
SPINAL-CORD
MORPHINE-TOLERANCE
SENSORY NEURONS
MESSENGER-RNAS
KNOCKOUT MICE
MU-RECEPTOR
Phosphorylation of TRPV1 by cyclin-dependent kinase 5 promotes TRPV1 surface localization, leading to inflammatory thermal hyperalgesia
期刊论文
EXPERIMENTAL NEUROLOGY, 2015
Liu, Jiao
;
Du, Junxie
;
Yang, Yanrui
;
Wang, Yun
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2017/12/03
Cdk5
TRPV1
Phosphorylation
Membrane trafficking
Hyperalgesia
PRIMARY SENSORY NEURONS
MORPHINE ANTINOCICEPTIVE TOLERANCE
CDK5 INHIBITORY PEPTIDE
PROTEIN-KINASE
HEAT HYPERALGESIA
NEUROTRANSMITTER RELEASE
NEURITE OUTGROWTH
PLASMA-MEMBRANE
NERVOUS-SYSTEM
FHA DOMAIN
Opioid receptor trafficking and interaction in nociceptors
期刊论文
BRITISH JOURNAL OF PHARMACOLOGY, 2015, 卷号: 172, 期号: 2, 页码: 364-374
作者:
Zhang, X
;
Bao, L
;
Li, S
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2015/07/22
-opioid receptor
-opioid receptor
nociceptor
dorsal root ganglion
receptor trafficking
receptor interaction
morphine antinociceptive tolerance
Pharmacological characterization and therapeutic potential for the treatment of opioid abuse with ATPM-ET, an N-ethyl substituted aminothiazolomorphinan with kappa agonist and mu agonist/antagonist activity
期刊论文
EUROPEAN JOURNAL OF PHARMACOLOGY, 2014, 卷号: 740, 页码: 455-463
作者:
Sun, Jian-Feng
;
Wang, Yu-Hua
;
Chai, Jing-Rui
;
Li, Fu-Ying
;
Hang, Ai
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2019/01/08
kappa against and mu agonistfantagonist
Antinociception
Sedation
CPP
Heroin self-administration
Reinstatement of drug seeking behavior
Resveratrol attenuates morphine antinociceptive tolerance via SIRT1 regulation in the rat spinal cord
期刊论文
Neuroscience letters, 2014, 卷号: 566, 页码: 55-60
作者:
He, Xin
;
Ou, Peng
;
Wu, Kemin
;
Huang, Changsheng
;
Wang, Yichun
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2019/12/03
Ac-H3
Morphine tolerance
Rat
Resveratrol
SIRT1
Spinal cord
A Novel Role of Spinal Astrocytic Connexin 43: Mediating Morphine Antinociceptive Tolerance by Activation of NMDA Receptors and Inhibition of Glutamate Transporter-1 in Rats (SCI收录)
期刊论文
CNS NEUROSCIENCE & THERAPEUTICS, 2014, 卷号: 20, 页码: 728-736
作者:
Shen, Ning[1]
;
Mo, Li-Qiu[2]
;
Hu, Fen[3]
;
Chen, Pei-Xi[1]
;
Guo, Rui-Xian[1]
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2019/04/25
Astrocyte
Connexin 43
Glutamate transporter-1
Morphine tolerance
N-methyl-D-aspartic acid receptor
Spinal leptin contributes to the development of morphine antinociceptive tolerance by activating the STAT3-NMDA receptor pathway in rats
期刊论文
MOLECULAR MEDICINE REPORTS, 2014, 卷号: 10, 页码: 923-930
作者:
Hu, Fen[1]
;
Cui, Yu[1]
;
Guo, Ruixian[1]
;
Chen, Jingfu[2]
;
Guo, Runming[2]
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2019/04/25
morphine antinociceptive tolerance
leptin
STAT3
NMDA receptor
spinal cord
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