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Recent advances in dopaminergic strategies for the treatment of Parkinson's disease
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 12
作者:
Mao, Qi
;
Qin, Wang-zhi
;
Zhang, Ao
;
Ye, Na
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2020/07/01
Parkinson's disease
dopamine
D-1 receptor
D-2 receptor
allosteric modulator
neuroprotection
multitarget
drug discovery and development
neurodegenerative diseases
Chemical Composition and Biological Activities of Endophytic Fungus Talaromyces Wortmannii LGT-4, Cultured in CYM Medium
期刊论文
IRANIAN JOURNAL OF PHARMACEUTICAL RESEARCH, 2020, 卷号: 19, 期号: 2, 页码: 259-263
作者:
Yang, Zhong-Duo
;
Zhang, Yu
;
Zhao, Wei-Hua
;
Shu, Zong-Mei
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2022/03/01
Endophytic fungus
Monoamine oxidase inhibitors
Chemical composition
Talaromyces wortmannii
Tripterygium wilfordi
Identification of novel monoamine oxidase selective inhibitors employing a hierarchical ligand-based virtual screening strategy
期刊论文
FUTURE MEDICINAL CHEMISTRY, 2019, 卷号: 11, 期号: 8, 页码: 801-816
作者:
Wang, Dong
;
Li, Zhaoyang
;
Liu, Yi
;
Chen, Mo
;
Chen, Nianhang
收藏
  |  
浏览/下载:46/0
  |  
提交时间:2019/09/10
BRS-3D
monoamine oxidase selective inhibitors
virtual screening
Wortmannine F and G, two new pyranones from Talaromyces wortmannii LGT-4, the endophytic fungus of Tripterygium wilfordii
期刊论文
PHYTOCHEMISTRY LETTERS, 2019, 卷号: 29, 页码: 115-118
作者:
Zhao, Jun-Wen
;
Yang, Zhong-Duo
;
Zhou, Shuan-Yan
;
Yang, Li-Jun
;
Sun, Jian-Hui
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2019/11/15
Wortmannine
Talaromyces wortmannii
Endophytic fungus
Phosphoinositide 3-kinase inhibitors
Wortmannine F and G, two new pyranones from Talaromyces wortmannii LGT-4, the endophytic fungus of Tripterygium wilfordii
期刊论文
PHYTOCHEMISTRY LETTERS, 2019, 卷号: 29, 页码: 115-118
作者:
Zhao, Jun-Wen
;
Yang, Zhong-Duo
;
Zhou, Shuan-Yan
;
Yang, Li-Jun
;
Sun, Jian-Hui
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2022/03/01
Wortmannine
Talaromyces wortmannii
Endophytic fungus
Phosphoinositide 3-kinase inhibitors
Monoamine oxidase inhibitors protect against coronary heart disease in rodent rat models: A pilot study
期刊论文
PAKISTAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2019, 卷号: 32, 期号: 1
作者:
Zhang, Weihua
;
Shao, Wangshu
;
Shu, Shangzhi
;
Liu, Rui
;
Jiang, Yaqiu
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2019/12/05
Hypertrophy
monoamine oxidase
angiotensin II
befloxatone
ejection fraction
rats
Discovery, synthesis, biological evaluation and molecular docking study of (R)-5-methylmellein and its analogs as selective monoamine oxidase A inhibitors
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2019, 卷号: 27, 期号: 10
作者:
Lei, Xinsheng
;
Hu, Jin-Feng
;
Guan, Hui-Da
;
Wang, Chang-Hong
;
Huang, Chao
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  |  
浏览/下载:45/0
  |  
提交时间:2019/12/05
Natural product
5-Methylmellein
Synthetic analogs
Monoamine oxidase
Inhibitor
Discovery, synthesis, biological evaluation and molecular docking study of (R)-5-methylmellein and its analogs as selective monoamine oxidase A inhibitors
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2019, 卷号: 27, 期号: 10
作者:
Huang, Chao
;
Xiong, Juan
;
Guan, Hui-Da
;
Wang, Chang-Hong
;
Lei, Xinsheng
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2019/12/05
Natural product
5-Methylmellein
Synthetic analogs
Monoamine oxidase
Inhibitor
Design, synthesis and biological evaluation of novel human monoamine oxidase B inhibitors based on a fragment in an X-ray crystal structure.
期刊论文
Bioorganic & medicinal chemistry letters, 2019
作者:
Kai Cheng
;
Shiyu Li
;
Xiao Lv
;
Yongbin Tian
;
Haiyan Kong
收藏
  |  
浏览/下载:71/0
  |  
提交时间:2019/12/13
Fragment-based drug design
Isatin
Isoform selectivity
Structure activity relationship
hMAO-B
Discovery of novel 2,3-dihydro-1H-inden-1-amine derivatives as selective monoamine oxidase B inhibitors
期刊论文
Bioorganic & Medicinal Chemistry Letters, 2019
作者:
Shiyu Li
;
Xiao Lv
;
Kai Cheng
;
Yongbing Tian
;
Xufeng Huang
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2019/12/13
Monoamine oxidase B
Selectivity
2,3-dihydro-1H-inden-1-amine
Structure activity relationship
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