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浏览/检索结果: 共10条，第1-10条 帮助 已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 Two New Cytotoxic Maytansinoids Targeting Tubulin from Trewia nudiflora 期刊论文 PLANTA MEDICA, 2021, 页码: 7 作者:  Lei, Chun;  Li, Ya-Nan;  Li, Jia-Nan;  Zhou, Yu-Bo;  Cui, Ming-Jun 收藏  |  浏览/下载：21/0  |  提交时间：2021/12/16 Trewia nudiflora  Euphorbiaceae  maytansinoids  cytotoxicity  tubulin polymerization   Synthesis and bioactivity studies of covalent inhibitors derived from (-)-Chaetominine 期刊论文 JOURNAL OF MOLECULAR STRUCTURE, 2021, 卷号: 1241, 页码: 14 作者:  Zhou, Xian;  Feng, Xuexin;  Wang, Dachi;  Chen, Deheng;  Wu, Gaoxing 收藏  |  浏览/下载：85/0  |  提交时间：2021/08/17 Chaetominine  Cellular growth inhibition  Cancer cell line  Covalent warhead   Design, synthesis, and biological evaluation of 4-benzoylamino-1H-pyrazole-3-carboxamide derivatives as potent CDK2 inhibitors 期刊论文 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 215, 页码: 12 作者:  Lin, Tingting;  Li, Jiacheng;  Liu, Liping;  Li, Yuanqing;  Jiang, Hualiang 收藏  |  浏览/下载：70/0  |  提交时间：2021/05/24 CDK2 inhibitor  Selectivity  Anti-proliferative potency   Structure-based drug optimization and biological evaluation of tetrahydroquinolin derivatives as selective and potent CBP bromodomain inhibitors 期刊论文 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2020, 卷号: 30, 期号: 22, 页码: 7 作者:  Bi, Xiaoyang;  Chen, Yu;  Sun, Zhongya;  Lu, Wenchao;  Xu, Pan 收藏  |  浏览/下载：21/0  |  提交时间：2021/05/24 Drug design  CBP  Bromodomain  Inhibitor  Acute myeloid leukemia   Hyperprins A and B, Two Complex Meroterpenoids from Hypericum przewalskii 期刊论文 ORGANIC LETTERS, 2020, 卷号: 22, 期号: 7, 页码: 2797-2800 作者:  Zong, Jian-Fa;  Hu, Zhu;  Shao, Ying-Ying;  Shi, Qing;  Zhang, Meng-Meng 收藏  |  浏览/下载：27/0  |  提交时间：2020/07/01 Design, Synthesis, and In Vitro Evaluation of Benzofuro[3,2-c]Quinoline Derivatives as Potential Antileukemia Agents 期刊论文 MOLECULES, 2020, 卷号: 25, 期号: 1, 页码: 13 作者:  Lin, Ying;  Xing, Dong;  Wu, Wen-Biao;  Xu, Gao-Ya;  Yu, Li-Fang 收藏  |  浏览/下载：17/0  |  提交时间：2020/07/01 benzofuro[3,2-c]quinolines  3-(2-methoxyphenyl)quinolin-4(1H)one  MV-4-11 cell line  antileukemia activity   Antiproliferative Sesquiterpenoids from Ligularia rumicifolia with Diverse Skeletons 期刊论文 JOURNAL OF NATURAL PRODUCTS, 2018, 卷号: 81, 期号: 9, 页码: 1992-2003 作者:  Ye, Ye;  Dawa, Drolma;  Liu, Guang-Hui;  Zhao, Min;  Tseden, Dorje 收藏  |  浏览/下载：14/0  |  提交时间：2020/12/24 Design, synthesis and biological evaluation of benzo[cd]indo1-2(1H)-ones derivatives as BRD4 inhibitors 期刊论文 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 152, 页码: 264-273 作者:  Feng, Yuxin;  Xiao, Senhao;  Chen, Yantao;  Jiang, Hao;  Liu, Na 收藏  |  浏览/下载：35/0  |  提交时间：2019/01/08 Benzo[cd]indol-2(1H)-one  Sulfonamide  BRD4 inhibitor  Bromodomain and extra-terminal domain  Acetyl-lysine binding pocket   Identification of a novel selective small-molecule inhibitor of protein arginine methyltransferase 5 (PRMT5) by virtual screening, resynthesis and biological evaluations 期刊论文 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2018, 卷号: 28, 期号: 9, 页码: 1476-1483 作者:  Zhu, Kongkai;  Jiang, Chengshi;  Tao, Hongrui;  Liu, Jingqiu;  Zhang, Hua 收藏  |  浏览/下载：59/0  |  提交时间：2019/01/08 PRMT5 inhibitor  Resynthesis  Virtual screening  Molecular docking  Molecular dynamics simulation   Design, synthesis and biological evaluation of indolin-2-one-based derivatives as potent, selective and efficacious inhibitors of FMS-like tyrosine kinase3 (FLT3) 期刊论文 European journal of medicinal chemistry, 2017, 卷号: 127, 页码: 72-86 作者:  Ma, Fei;  Liu, Peng;  Lei, Min;  Liu, Jian;  Wang, Hongtao 收藏  |  浏览/下载：12/0  |  提交时间：2019/01/08