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The ancient CgPEPCK-1, not CgPECK-2, evolved into a multifunctional molecule as an intracellular enzyme and extracellular PRR
期刊论文
DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY, 2023, 卷号: 145, 页码: 13
作者:
Yin, Xiaoting
;
Qiu, Limei
;
Long, Dandan
;
Lv, Zhao
;
Liu, Qing
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2023/12/13
PEPCK
Gene evolution and differentiation
PRR
Catalyzing enzyme
Characteristic and antibacterial effect of a histone H2A and its preliminary roles in extracellular traps in manila clam Ruditapes philippinarum
期刊论文
FISH & SHELLFISH IMMUNOLOGY, 2022, 卷号: 131, 页码: 77-83
作者:
Lv, Xiaojing
;
Jiao, Chunli
;
Chen, Yuying
;
Chen, Lizhu
;
Li, Xuan
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2023/01/11
Ruditapes philippinarum
Histone
Antimicrobial activity
Extracellular traps
Characteristic and antibacterial effect of a histone H2A and its preliminary roles in extracellular traps in manila clam Ruditapes philippinarum
期刊论文
FISH & SHELLFISH IMMUNOLOGY, 2022, 卷号: 131, 页码: 77-83
作者:
Lv, Xiaojing
;
Jiao, Chunli
;
Chen, Yuying
;
Chen, Lizhu
;
Li, Xuan
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2023/01/11
Ruditapes philippinarum
Histone
Antimicrobial activity
Extracellular traps
A Type Ib Crustin from Deep-Sea Shrimp Possesses Antimicrobial and Immunomodulatory Activity
期刊论文
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2022, 卷号: 23, 期号: 12, 页码: 14
作者:
Wang, Yu-Jian
;
Sun, Li
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2022/07/18
crustin
WAP domain
bactericidal
deep-sea
Potent and Selective RIPK1 Inhibitors Targeting Dual-Pockets for the Treatment of Systemic Inflammatory Response Syndrome and Sepsis
期刊论文
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2021, 页码: 6
作者:
Yang, Xiangbo
;
Lu, Huimin
;
Xie, Hang
;
Zhang, Binbin
;
Nie, Tianqing
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2022/01/18
Binding studies
Drug discovery
Necroptosis
RIPK1 inhibitors
Sepsis
STING inhibitor ameliorates LPS-induced ALI by preventing vascular endothelial cells-mediated immune cells chemotaxis and adhesion
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 12
作者:
Wu, Bing
;
Xu, Meng-meng
;
Fan, Chen
;
Feng, Chun-lan
;
Lu, Qiu-kai
收藏
  |  
浏览/下载:59/0
  |  
提交时间:2022/01/18
acute lung injury
STING
vascular endothelial cells
inflammatory cytokines
chemokines
chemotaxis
A g-Type Lysozyme from Deep-Sea Hydrothermal Vent Shrimp Kills Selectively Gram-Negative Bacteria
期刊论文
MOLECULES, 2021, 卷号: 26, 期号: 24, 页码: 14
作者:
Luo, Jing-Chang
;
Zhang, Jian
;
Sun, Li
收藏
  |  
浏览/下载:42/0
  |  
提交时间:2022/02/18
g-type lysozyme
shrimp
deep-sea hydrothermal vent
non-enzymatic antibacterial activity
Ainsliadimer C, a disesquiterpenoid isolated from Ainsliaea macrocephala, ameliorates inflammatory responses in adipose tissue via Sirtuin 1-NLRP3 inflammasome axis
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 13
作者:
Chen, Cheng
;
Ren, Yong-mei
;
Zhu, Jian-zhong
;
Chen, Jia-li
;
Feng, Zhe-ling
收藏
  |  
浏览/下载:56/0
  |  
提交时间:2022/01/04
Ainsliadimer C
interleukin-1 beta
macrophages
NLRP3 inflammasome
Sirtuin 1
adipose tissue inflammation
obesity
metabolic disorders
EX-527
dexamethasone
Identification of phosphodiesterase-4 as the therapeutic target of arctigenin in alleviating psoriatic skin inflammation
期刊论文
JOURNAL OF ADVANCED RESEARCH, 2021, 卷号: 33, 页码: 241-251
作者:
Li, Heng
;
Zhang, Xianglei
;
Xiang, Caigui
;
Feng, Chunlan
;
Fan, Chen
收藏
  |  
浏览/下载:87/0
  |  
提交时间:2021/11/04
PDE4
Arctigenin
Psoriasis
Inflammation
Targeting sorting nexin 10 improves mouse colitis via inhibiting PIKfyve-mediated TBK1/c-Rel signaling activation
期刊论文
PHARMACOLOGICAL RESEARCH, 2021, 卷号: 169, 页码: 11
作者:
Bao, Weilian
;
Liu, Xiaohong
;
You, Yan
;
Hou, Hui
;
Wang, Xu
收藏
  |  
浏览/下载:58/0
  |  
提交时间:2021/11/16
SNX10
IBD
Macrophage
PIKfyve
TBK1
PPI inhibitor
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