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上海药物研究所 [19]
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Comparative study of the immunomodulatory effects of different fucoidans from Saccharina japonica mediated by scavenger receptors on RAW 264.7 macrophages
期刊论文
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2022, 卷号: 215, 页码: 253-261
作者:
Cui, Meiyu
;
Li, Xiaohong
;
Geng, Lihua
;
Wu, Ning
;
Wang, Jing
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2022/08/17
Fucoidan
Saccharina japonica
Scavenger receptor
Macrophage
SR-A
CD36
LOX-1
Immunomodulatory
Oxidized Low-Density Lipoprotein Links Hypercholesterolemia and Bladder Cancer Aggressiveness by Promoting Cancer Stemness
期刊论文
CANCER RESEARCH, 2021, 卷号: 81, 期号: 22, 页码: 5720-5732
作者:
Yang, Lin
;
Sun, Jingya
;
Li, Meiqian
;
Long, Yiming
;
Zhang, Dianzheng
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2022/01/04
23,24-Dihydrocucurbitacin B promotes lipid clearance by dual transcriptional regulation of LDLR and PCSK9
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 卷号: 41, 期号: 3, 页码: 327-335
作者:
Li, Hui-hui
;
Li, Jun
;
Zhang, Xian-jing
;
Li, Jiao-meng
;
Xi, Cong
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2020/07/01
23,24-dihydrocucurbitacin B
lipid-lowering agent
LDLR
PCSK9
HNF1 alpha
SREBP2
Recent progress in the detection and treatment of atherosclerosis by nanoparticles
期刊论文
MATERIALS TODAY CHEMISTRY, 2020, 卷号: 17
作者:
Chen, L.
;
Jiang, Z.
;
Akakuru, O. U.
;
Yang, L.
;
Li, J.
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2020/12/16
MAGNETIC-RESONANCE
MRI DETECTION
MACROPHAGES
INFLAMMATION
PLAQUE
RECEPTOR
DELIVERY
LESIONS
REDUCTION
TISSUE
2324dihydrocucurbitacinbpromoteslipidclearancebydualtranscriptionalregulationofldlrandpcsk9
期刊论文
actapharmacologicasinica, 2020, 卷号: 41, 期号: 3, 页码: 327
作者:
Li Huihui
;
Li Jun
;
Zhang Xianjing
;
Li Jiaomeng
;
Xi Cong
收藏
  |  
浏览/下载:42/0
  |  
提交时间:2020/07/01
23
24-dihydrocucurbitacin B
lipid-lowering agent
LDLR
PCSK9
HNF1α
SREBP2
Design, synthesis, and biological evaluation of novel tetrahydroprotoberberine derivatives (THPBs) as proprotein convertase subtilisin/kexin type 9 (PCSK9) modulators for the treatment of hyperlipidemia
期刊论文
ACTA PHARMACEUTICA SINICA B, 2019, 卷号: 9, 期号: 6, 页码: 1216-1230
作者:
Wu, Chenglin
;
Xi, Cong
;
Tong, Junhua
;
Zhao, Jing
;
Jiang, Hualiang
收藏
  |  
浏览/下载:46/0
  |  
提交时间:2020/07/01
PCSK9
Tetrahydroprotoberberine derivatives
Low-density lipoprotein cholesterol
Lipid-lowering
PCSK9 expression
Low-density lipoprotein receptor
Total cholesterol
Hyperlipidemia hamster
Blocking P2X7 receptor ameliorates oxidized LDL-mediated podocyte apoptosis
期刊论文
MOLECULAR BIOLOGY REPORTS, 2019, 卷号: 46, 期号: 4, 页码: 3809-3816
作者:
Zhu, Yanji
;
Li, Qian
;
Xun, Wenlong
;
Chen, Yuan
;
Zhang, Caihui
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2019/12/11
oxLDL
Podocyte
P2X7R
ROS
Bax
Caspase-3
Astragaloside IV protects endothelial progenitor cells from the damage of ox-LDL via the LOX-1/ NLRP3 inflammasome pathway
期刊论文
Drug Design, Development and Therapy, 2019, 卷号: 13, 页码: 2579-2589
作者:
Qian W.
;
Cai X.
;
Qian Q.
;
Zhuang Q.
;
Yang W.
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2019/12/11
Astragaloside IV
Endothelial progenitor cells
Lectin-like oxidized LDL receptor
NLRP3 inflammasome
Astragaloside IV protects endothelial progenitor cells from the damage of ox-LDL via the LOX-I/NLRP3 inflammasome pathway
期刊论文
DRUG DESIGN DEVELOPMENT AND THERAPY, 2019, 卷号: 13, 页码: 2579-2589
作者:
Qian, Weibin
;
Cai, Xinrui
;
Qian, Qiuhai
;
Zhuang, Qianzhu
;
Yang, Wenjun
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2019/12/11
endothelial progenitor cells
astragaloside IV
lectin-like oxidized LDL
receptor
NLRP3 inflammasome
PCSK9 Inhibitors: Novel Therapeutic Strategies for Lowering LDL-Cholesterol
期刊论文
MINI-REVIEWS IN MEDICINAL CHEMISTRY, 2019, 卷号: 19, 期号: 2, 页码: 165-176
作者:
Wang, Yan
;
Liu, Zhao-Peng
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2019/12/11
Proprotein convertase subtilisin/kexin type 9 inhibitors (PCSK9)
low-density lipoprotein cholesterol (LDL-C)
low-density lipoprotein
receptor (LDLR)
cardiovascular disease (CVD)
hypercholesterolemia
alirocmab
evolocumab
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