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Repurposing of the FGFR inhibitor AZD4547 as a potent inhibitor of necroptosis by selectively targeting RIPK1
期刊论文
ACTA PHARMACOLOGICA SINICA, 2022
作者:
Wang, Zuo-wei
;
Zou, Feng-ming
;
Wang, Ao-li
;
Yang, Jing
;
Jin, Rui
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2022/12/22
AZD4547
RIPK1
inhibitors
SIRS model
anti-necroptosis
Protein disulfide isomerase blocks the interaction of LC3II-PHB2 and promotes mTOR signaling to regulate autophagy and radio/chemo-sensitivity
期刊论文
CELL DEATH & DISEASE, 2022, 卷号: 13
作者:
Wang, Ruru
;
Shang, Yajing
;
Chen, Bin
;
Xu, Feng
;
Zhang, Jie
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2022/12/22
Drug-resistant HER2-positive breast cancer: Molecular mechanisms and overcoming strategies
期刊论文
FRONTIERS IN PHARMACOLOGY, 2022, 卷号: 13
作者:
Wu, Xiaofan
;
Yang, Hongjian
;
Yu, Xingfei
;
Qin, Jiang-Jiang
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2022/12/22
HER2
breast cancer
targeted therapy
drug resistance
overcoming strategies
Peptidic microarchitecture-trapped tumor vaccine combined with immune checkpoint inhibitor or PI3K gamma inhibitor can enhance immunogenicity and eradicate tumors
期刊论文
JOURNAL FOR IMMUNOTHERAPY OF CANCER, 2022, 卷号: 10, 期号: 2, 页码: 13
作者:
Du, Yang
;
Liu, Ye
;
Wang, Di
;
Bai, Hua
;
Wang, Zhijie
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2022/06/06
immunotherapy
immunogenicity
vaccine
tumor microenvironment
lymphocytes
tumor infiltrating
macrophages
Identification of novel anti-inflammatory Nur77 modulators by virtual screening
期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 112, 页码: 7
作者:
Ding, Xiaoyu
;
Zhao, Zijie
;
Wu, Yue
;
Zhang, Hao
;
Chen, Kaixian
收藏
  |  
浏览/下载:46/0
  |  
提交时间:2021/08/17
Nur77
Binding site evaluation
Virtual Screening
Inflammation
Prevention of D-GalN/LPS-induced ALI by 18 beta-glycyrrhetinic acid through PXR-mediated inhibition of autophagy degradation
期刊论文
CELL DEATH & DISEASE, 2021, 卷号: 12, 期号: 5, 页码: 13
作者:
Wu, Shouyan
;
Lu, Henglei
;
Wang, Wenjie
;
Song, Luyao
;
Liu, Meng
收藏
  |  
浏览/下载:42/0
  |  
提交时间:2021/08/17
Cediranib Induces Apoptosis, G1 Phase Cell Cycle Arrest, and Autophagy in Non-Small-Cell Lung Cancer Cell A549 In Vitro
期刊论文
BIOMED RESEARCH INTERNATIONAL, 2021, 卷号: 2021, 页码: 11
作者:
Guo, Menghuan
;
Liu, Zhiyuan
;
Si, Jing
;
Zhang, Jinhua
;
Zhao, Jin
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2021/12/10
Engineering Nanoscale Artificial Antigen-Presenting Cells by Metabolic Dendritic Cell Labeling to Potentiate Cancer Immunotherapy
期刊论文
NANO LETTERS, 2021, 卷号: 21, 期号: 5, 页码: 2094-2103
作者:
Xiao, Ping
;
Wang, Jue
;
Zhao, Zitong
;
Liu, Xiaochen
;
Sun, Xiangshi
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2021/05/24
nanoscale
artificial antigen-presenting cells
metabolic cell labeling
dendritic cells
cancer immunotherapy
Genomic profiles and tumor immune microenvironment of primary lung carcinoma and brain oligo-metastasis
期刊论文
CELL DEATH & DISEASE, 2021, 卷号: 12
作者:
Song, Zhengbo
;
Yang, Ling
;
Zhou, Zhipeng
;
Li, Pansong
;
Wang, Wenxian
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2021/08/30
DW14006 as a direct AMPK alpha 1 activator improves pathology of AD model mice by regulating microglial phagocytosis and neuroinflammation
期刊论文
BRAIN BEHAVIOR AND IMMUNITY, 2020, 卷号: 90, 页码: 55-69
作者:
Lv, Jianlu
;
Wang, Wei
;
Zhu, Xialin
;
Xu, Xiaoju
;
Yan, Qiuying
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2020/12/21
Alzheimer'sdisease
Microglia
AMPK alpha 1
DW14006
Phagocytosis
Neuro-inflammation
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