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科研机构
上海药物研究所 [5]
厦门大学 [1]
四川大学 [1]
内容类型
期刊论文 [7]
发表日期
2021 [2]
2020 [1]
2011 [1]
2010 [1]
2007 [1]
2004 [1]
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A camptothecin-based, albumin-binding prodrug enhances efficacy and safety in vivo
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 226, 页码: 11
作者:
Cheng, Zhiyang
;
Huang, Ying
;
Shen, Qianqian
;
Zhao, Yangrong
;
Wang, Lei
收藏
  |  
浏览/下载:86/0
  |  
提交时间:2021/11/04
Cancer
beta-glucuronidase
Bioconjugation
Albumin
Camptothecin
A validated HPLC-MS/MS method for determination of simmitecan and its metabolite chimmitecan in human plasma and its application to a pharmacokinetic study in Chinese patients with advanced solid tumor
期刊论文
JOURNAL OF SEPARATION SCIENCE, 2021, 页码: 8
作者:
Zhou, Jun
;
Zhan, Yan
;
Zhong, Dafang
;
Chen, Xiaoyan
;
Zhang, Yifan
收藏
  |  
浏览/下载:72/0
  |  
提交时间:2021/11/04
chimmitecan
mass spectrometry
pharmacokinetics
simmitecan
solid tumors
The role of critical micellization concentration in efficacy and toxicity of supramolecular polymers
期刊论文
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2020, 卷号: 117, 期号: 9, 页码: 4518-4526
作者:
Su, Hao
;
Wang, Feihu
;
Ran, Wei
;
Zhang, Weijie
;
Dai, Wenbing
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2020/07/01
critical micellization concentration
molecular assembly
supramolecular polymers
drug delivery
prodrugs
PLA Nanoparticles Loaded With an Active Lactone Form of Hydroxycamptothecin: Development, Optimization, and In Vitro-In Vivo Evaluation in Mice Bearing H22 Solid Tumor
期刊论文
http://dx.doi.org/10.1002/ddr.20435, 2011
Hou, Zhenqing
;
Zhou, Chunxiao
;
Luo, Ying
;
Zhan, Chuanming
;
Wang, Yixiao
;
Xie, Liya
;
Zhang, Qiqing
;
张其清
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2013/12/12
ANTITUMOR CHARACTERISTICS
CAMPTOTHECIN DELIVERY
DRUG-DELIVERY
SERUM-ALBUMIN
10-HYDROXYCAMPTOTHECIN
MICROSPHERES
FORMULATION
SYSTEMS
A novel composite hydrogel based on chitosan and inorganic phosphate for local drug delivery of camptothecin nanocolloids
期刊论文
Journal of Pharmaceutical Sciences, 2010
-
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/03/05
Animals
Antineoplastic
Agents,
Phytogenic/*administration
&
dosage/pharmacology
Camptothecin/*administration
&
dosage/pharmacology
Cell
Line,
Tumor
Chemistry,
Pharmaceutical
Chitosan/*chemistry/toxicity
Colloids
Delayed-Action
Preparations/administration
&
dosage/pharmacology
Drug
Carriers/*administration
&
dosage/pharmacology
Drug
Delivery
Systems/*methods
Drug
Stability
Female
Humans
Hydrogels
Kinetics
Mice
Mice,
Inbred
BALB
C
Nanostructures/*chemistry/toxicity/ultrastructure
Ovarian
Neoplasms/drug
therapy
Phosphates/*chemistry/toxicity
Physicochemical
Phenomena
Chimmitecan, a novel 9-substituted camptothecin, with improved anticancer pharmacologic profiles in vitro and in vivo
期刊论文
CLINICAL CANCER RESEARCH, 2007, 卷号: 13, 期号: 4, 页码: 1298-1307
作者:
Huang, Min
;
Gao, Heyong
;
Chen, Yi
;
Zhu, Hong
;
Cai, Yujun
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2019/01/08
Camptothecin derivative-loaded poly(caprolactone-co-lactide)-b-PEG-b-poly(caprolactone-co-lactide) nanoparticles and their biodistribution in mice
期刊论文
JOURNAL OF CONTROLLED RELEASE, 2004, 卷号: 96, 期号: 1, 页码: 135-148
作者:
Zhang, LY
;
Hu, Y
;
Jiang, XQ
;
Yang, CZ
;
Lu, W
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2019/01/08
nanoparticles
block copolymers
drug delivery systems
camptothecin
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