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Berberine derivatives with a long alkyl chain branched by hydroxyl group and methoxycarbonyl group at 9-position show improved anti-proliferation activity and membrane permeability in A549 cells 期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 12
作者:  Liu, Yi;  Zhu, Ke-xin;  Cao, Lei;  Xie, Zhi-fu;  Gu, Min
收藏  |  浏览/下载:15/0  |  提交时间:2020/07/01
Berberine and its structural analogs have differing effects on functional profiles of individual gut microbiomes 期刊论文
GUT MICROBES, 2020, 卷号: 11, 期号: 5, 页码: 1348-1361
作者:  Li, Leyuan;  Chang, Lu;  Zhang, Xu;  Ning, Zhibin;  Mayne, Janice
收藏  |  浏览/下载:15/0  |  提交时间:2020/12/24
Design, synthesis, and biological evaluation of novel tetrahydroprotoberberine derivatives (THPBs) as proprotein convertase subtilisin/kexin type 9 (PCSK9) modulators for the treatment of hyperlipidemia 期刊论文
ACTA PHARMACEUTICA SINICA B, 2019, 卷号: 9, 期号: 6, 页码: 1216-1230
作者:  Wu, Chenglin;  Xi, Cong;  Tong, Junhua;  Zhao, Jing;  Jiang, Hualiang
收藏  |  浏览/下载:46/0  |  提交时间:2020/07/01
designsynthesisandbiologicalevaluationofnoveltetrahydroprotoberberinederivativesthpbsasproproteinconvertasesubtilisinkexintype9pcsk9modulatorsforthetreatmentofhyperlipidemia 期刊论文
actapharmaceuticasinicab, 2019, 卷号: 9, 期号: 6, 页码: 1216
作者:  Wu Chenglin;  Xi Cong;  Tong Junhua;  Zhao Jing;  Jiang Hualiang
收藏  |  浏览/下载:52/0  |  提交时间:2020/07/01
Design, synthesis, and structure-activity relationships of novel 4,7,12,12a-tetrahydro-5H-thieno[3 ',2 ':3,4]pyrido[1,2-b]isoquinoline and 5,8,12,12a-tetrahydro-6H-thieno[2 ',3 ': 4,5]pyrido[2,1-a]isoquinoline derivatives as cellular activators of adenosine 5 '-monophosphate-activated protein kinase (AMPK) 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2018, 卷号: 26, 期号: 8, 页码: 2017-2027
作者:  Gu, Zhanni;  Wu, Lingyan;  Duan, Yanan;  Wang, Jiang;  Zhou, Shengbin
收藏  |  浏览/下载:39/0  |  提交时间:2019/01/08
Synthesis and Evolution of Berberine Derivatives as a New Class of Antiviral Agents against Enterovirus 71 through the MEK/ERK Pathway and Autophagy 期刊论文
2018, 卷号: 23, 期号: 8
作者:  Wang, Yan-Xiang;  Yang, Lu;  Wang, Hui-Qiang;  Zhao, Xiao-Qiang;  Liu, Ting
收藏  |  浏览/下载:3/0  |  提交时间:2020/01/03
Discovery and Development of 8-Substituted Cycloberberine Derivatives as Novel Antibacterial Agents against MRSA 期刊论文
2018, 卷号: 9, 期号: 5, 页码: 484-489
作者:  Fan, Tianyun;  Hu, Xinxin;  Tang, Sheng;  Liu, Xiaojia;  Wang, Yanxiang
收藏  |  浏览/下载:10/0  |  提交时间:2020/01/03
Synthesis and biological evaluation of new berberine derivatives as cancer immunotherapy agents through targeting IDO1 期刊论文
2018, 卷号: 143, 页码: 1858-1868
作者:  Wang, Yan-Xiang;  Pang, Wei-Qiang;  Zeng, Qing-Xuan;  Deng, Zhe-Song;  Fan, Tian-Yun
收藏  |  浏览/下载:9/0  |  提交时间:2020/01/03
Synthesis and Anticancer Activity of 9-O-Pyrazole Alkyl Substituted Berberine Derivatives. 期刊论文
ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY, 2018, 卷号: 18, 期号: 11, 页码: 1639-1648
作者:  Xiao, Daipeng;  He, Fen;  Peng, Dongming;  Zou, Min;  Peng, Junying
收藏  |  浏览/下载:13/0  |  提交时间:2019/12/27
Berberine Derivatives with Different Pharmacological Activities via Structural Modifications. 期刊论文
MINI-REVIEWS IN MEDICINAL CHEMISTRY, 2018, 卷号: 18, 期号: 17, 页码: 1424-1441
作者:  Xiao, Daipeng;  Liu, Zhenbao;  Zhang, Shanshan;  Zhou, Mi;  He, Fen
收藏  |  浏览/下载:10/0  |  提交时间:2019/12/27


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