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CORC

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JC-010a, a novel selective SHP2 allosteric inhibitor, overcomes RTK/non-RTK-mediated drug resistance in multiple oncogene-addicted cancers 期刊论文
CANCER LETTERS, 2024, 卷号: 582, 页码: 15
作者:  Lu, Xuxiu;  Yu, Rilei;  Li, Zhen;  Yang, Mengke;  Dai, Jiajia
收藏  |  浏览/下载：5/0  |  提交时间：2024/04/07
Discovery and characterization of a novel highly potent and selective type II native and drug-resistant V299L mutant BCR-ABL inhibitor (CHMFL-ABL-039) for Chronic Myeloid Leukemia (CML) 期刊论文
CANCER BIOLOGY & THERAPY, 2019, 卷号: 20, 期号: 6, 页码: 877-885
作者:  Wu, Jiaxin;  Wang, Aoli;  Li, Xixiang;  Chen, Cheng;  Qi, Ziping
收藏  |  浏览/下载：29/0  |  提交时间：2019/11/27
Comparison of Frequency and Sensitivity of BCR-ABL1 Kinase Domain Mutations in Asian and White Patients With Imatinib-resistant Chronice-Phase Chronic Myeloid Leukemia 期刊论文
CLINICAL LYMPHOMA MYELOMA & LEUKEMIA, 2018, 卷号: 18, 期号: 10
作者:  Cui, Jiu Wei;  Kim, Hawk;  Kim, SooHyun;  Kim, Hyeoung-Joon;  Kim, Yeo-Kyeoung
收藏  |  浏览/下载：13/0  |  提交时间：2019/12/05
Inhibition of 32Dp210 cells harboring T315I mutation by a novel derivative of emodin correlates with down-regulation of BCR-ABL and its downstream signaling pathways 期刊论文
JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY, 2015, 卷号: 141, 页码: 283-293
作者:  Li, Jing;  Chen, Yingyu;  Chen, Buyuan;  Chen, Cai;  Qiu, Binglin
收藏  |  浏览/下载：2/0  |  提交时间：2019/11/21
Characteristics of the TCR V beta repertoire in imatinib-resistant chronic myeloid leukemia patients with ABL mutations (SCI收录) 期刊论文
SCIENCE CHINA-LIFE SCIENCES, 2015, 卷号: 58, 页码: 1276-1281
作者:  Xu Ling[1];  Lu YuHong[2];  Lai Jing[1,2];  Yu Wei[3];  Zhang YiKai[1]
收藏  |  浏览/下载：3/0  |  提交时间：2019/04/25
Flumatinib, a selective inhibitor of BCR-ABL/PDGFR/KIT, effectively overcomes drug resistance of certain KIT mutants 期刊论文
CANCER SCIENCE, 2014, 卷号: 105, 期号: 1, 页码: 117-125
作者:  Zhao, Jie;  Quan, Haitian;  Xu, Yongping;  Kong, Xiangqian;  Jin, Lu
收藏  |  浏览/下载：28/0  |  提交时间：2019/01/08
Identification of GZD824 as an Orally Bioavailable Inhibitor That Targets Phosphorylated and Nonphosphorylated Breakpoint Cluster Region-Abelson (Bcr-Abl) Kinase and Overcomes Clinically Acquired Mutation-Induced Resistance against Imatinib 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2013, 卷号: 56, 期号: 3
作者:  Wang, Deping;  Feng, Yubing;  Zhuang, Xiaoxi;  Zhang, Fengxiang;  Liu, Jianqi
收藏  |  浏览/下载：23/0  |  提交时间：2018/12/13
Identification of GZD824 as an Orally Bioavailable Inhibitor That Targets Phosphorylated and Nonphosphorylated Breakpoint Cluster Region-Abelson (Bcr-Abl) Kinase and Overcomes Clinically Acquired Mutation-Induced Resistance against Imatinib 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2013, 卷号: 56, 期号: 3
Ren, Xiaomei; Pan, Xiaofen; Zhang, Zhang; Wang, Deping; Lu, Xiaoyun; Li, Yupeng; Wen, Donghai; Long, Huoyou; Luo, Jinfeng; Feng, Yubing; Zhuang, Xiaoxi; Zhang, Fengxiang; Liu, Jianqi; Leng, Fang; Lang, Xingfen; Bai, Yang; She, Miaoqin; Tu, Zhengchao; Pan, Jingxuan; Ding, Ke
收藏  |  浏览/下载：24/0  |  提交时间：2016/12/16
骨髓增殖性疾病中JAK2V617F基因突变及与临床特征的关系 期刊论文
中国实验血液学杂志, 2011, 卷号: 19, 期号: 4, 页码: 916-920
作者:  朱俊芳;  刘媛;  刘蓓;  贾明峰;  成娟
收藏  |  浏览/下载：2/0  |  提交时间：2016/09/12
AID expression is correlated with Bcr-Abl expression in CML-LBC and can be down-regulated by As2O3 and/or imatinib 期刊论文
LEUKEMIA RESEARCH, 2011, 卷号: 35, 期号: 10
作者:  Liu, ZiJie;  Wu, Xia;  Duan, Yong;  Wang, YuMing;  Shan, Bin
收藏  |  浏览/下载：4/0  |  提交时间：2019/12/04

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