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Small Molecule SHP2 Inhibitor LXQ-217 affects Lung Cancer Cell Proliferation in Vitro and in Vivo
期刊论文
CHEMISTRY & BIODIVERSITY, 2024, 页码: 11
作者:
Sun, Hao
;
Bai, Xiaoyi
;
Zhang, Yiting
;
Gao, Yanan
;
Dai, Jiajia
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2024/06/04
Anti-tumor
SHP2
Orthosteric inhibitor
Apoptosis
Bromophenol
JC-010a, a novel selective SHP2 allosteric inhibitor, overcomes RTK/non-RTK-mediated drug resistance in multiple oncogene-addicted cancers
期刊论文
CANCER LETTERS, 2024, 卷号: 582, 页码: 15
作者:
Lu, Xuxiu
;
Yu, Rilei
;
Li, Zhen
;
Yang, Mengke
;
Dai, Jiajia
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2024/04/07
Acquired resistance
Cancer
NSCLC
JC-010a
SHP2
Autophagy contributes to increase the content of intracellular free amino acids in hard clam
(Mercenaria
mercenaria)
during prolonged exposure to hypersaline environments
期刊论文
MARINE ENVIRONMENTAL RESEARCH, 2023, 卷号: 192, 页码: 11
作者:
Zhou, Cong
;
Yang, Mei-jie
;
Hu, Zhi
;
Zou, Yan
;
Shi, Pu
收藏
  |  
浏览/下载:122/0
  |  
提交时间:2023/11/30
Hyposalinity
Hypersalinity
Transcriptome
Autophagy
Free amino acids
Darinaparsin (ZIO-101) enhances the sensitivity of small-cell lung cancer to PARP inhibitors
期刊论文
ACTA PHARMACOLOGICA SINICA, 2022
作者:
Cao, Guo-Zhen
;
Ma, Li-Ying
;
Zhang, Zong-Hui
;
Wang, Xiao-Lin
;
Hua, Jing-Han
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2022/12/22
small-cell lung cancer
H3
3
PARP1
PARP inhibitor
darinaparsin
combination treatment
S3I-201 derivative incorporating naphthoquinone unit as effective STAT3 inhibitors: Design, synthesis and anti-gastric cancer evaluation
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2022, 卷号: 71
作者:
Li, Haobin
;
Cai, Maohua
;
Cao, Fei
;
Yu, Dehua
;
Yang, Jing
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2022/12/22
STAT3 inhibitor
Quinone derivative
S3I-201
Anti -gastric cancer drug
A near-infrared fluorescent probe was used to evaluate the role of histone deacetylase in pulmonary fibrosis cells and mice
期刊论文
SENSORS AND ACTUATORS B-CHEMICAL, 2022, 卷号: 366, 页码: 8
作者:
Wei, Yinghui
;
Hou, Junjun
;
Lu, Pengpeng
;
Fu, Lili
;
Wang, Xiaoyan
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2022/07/26
Fluorescent probe
Near-infrared
Histone deacetylases
Idiopathic pulmonary fibrosis
Fluorescence imaging
Regulation of the Cell Cycle, Apoptosis, and Proline Accumulation Plays an Important Role in the Stress Response of the Eastern Oyster Crassostrea Virginica
期刊论文
FRONTIERS IN MARINE SCIENCE, 2022, 卷号: 9, 页码: 12
作者:
Li, Cui
;
Wang, Haiyan
;
Guo, Ximing
收藏
  |  
浏览/下载:181/0
  |  
提交时间:2022/08/17
stress
transcriptome
cell cycle control
apoptosis
growth
immune function
epigenetic modification
Design, synthesis and biological evaluation of sulfonamides inhibitors of XPO1 displaying activity against multiple myeloma cells
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 235
作者:
Qu, Bingxue
;
Xu, Yongjin
;
Lu, Yang
;
Zhuang, Weihao
;
Jin, Xinxin
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2022/12/23
XPO1
Multiple myeloma
MM.1S
N-phenylsulfonamide
Oral administration
Characterization of a bioactive meroterpenoid isolated from the marine-derived fungus Talaromyces sp.
期刊论文
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, 2022, 卷号: 106
作者:
Hong, Xuan
;
Guan, Xiaoqing
;
Lai, Qiliang
;
Yu, Dehua
;
Chen, Zhongwei
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2022/05/16
Talaromyces
Meroterpenoid
Cytotoxic
Antibacterial
Inhibition of STAT3 Signaling Pathway by Terphenyllin Suppresses Growth and Metastasis of Gastric Cancer
期刊论文
FRONTIERS IN PHARMACOLOGY, 2022, 卷号: 13
作者:
Yu, Dehua
;
Qi, Simin
;
Guan, Xiaoqing
;
Yu, Wenkai
;
Yu, Xuefei
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2022/12/23
STAT3
inhibitor
natural product
gastric cancer
terphenyllin
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