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Small Molecule SHP2 Inhibitor LXQ-217 affects Lung Cancer Cell Proliferation in Vitro and in Vivo
期刊论文
CHEMISTRY & BIODIVERSITY, 2024, 页码: 11
作者:
Sun, Hao
;
Bai, Xiaoyi
;
Zhang, Yiting
;
Gao, Yanan
;
Dai, Jiajia
收藏
  |  
浏览/下载:0/0
  |  
提交时间:2024/06/04
Anti-tumor
SHP2
Orthosteric inhibitor
Apoptosis
Bromophenol
JC-010a, a novel selective SHP2 allosteric inhibitor, overcomes RTK/non-RTK-mediated drug resistance in multiple oncogene-addicted cancers
期刊论文
CANCER LETTERS, 2024, 卷号: 582, 页码: 15
作者:
Lu, Xuxiu
;
Yu, Rilei
;
Li, Zhen
;
Yang, Mengke
;
Dai, Jiajia
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2024/04/07
Acquired resistance
Cancer
NSCLC
JC-010a
SHP2
Proteomics Analysis Revealed Smad3 as a Potential Target of the Synergistic Anti-tumor Activity of Disulfiram and Cisplatin in Ovarian Cancer
期刊论文
ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY, 2023, 卷号: 23
作者:
Du, Ruiping
;
Sun, Feilong
;
Li, Kai
;
Qi, Jian
;
Zhong, Wen
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2023/11/10
Disulfiram
cisplatin resistance
ovarian cancer
proteomics analysis
SMAD3
lactate dehydrogenase
Darinaparsin (ZIO-101) enhances the sensitivity of small-cell lung cancer to PARP inhibitors
期刊论文
ACTA PHARMACOLOGICA SINICA, 2022
作者:
Cao, Guo-Zhen
;
Ma, Li-Ying
;
Zhang, Zong-Hui
;
Wang, Xiao-Lin
;
Hua, Jing-Han
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2022/12/22
small-cell lung cancer
H3
3
PARP1
PARP inhibitor
darinaparsin
combination treatment
Green synthesis of gold nanoparticles (AuNPs) using Caulerpa racemosa and evaluation of its antibacterial and cytotoxic activity against human lung cancer cell line
期刊论文
Arab Journal of Basic and Applied Sciences, 2022, 卷号: 29, 期号: 1, 页码: 352-362
作者:
Palaniappan Pitchai
;
Prabhu Subramani
;
Ramganesh Selvarajan
;
Renu Sankar
;
Ravikumar Vilwanathan
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2022/12/13
S3I-201 derivative incorporating naphthoquinone unit as effective STAT3 inhibitors: Design, synthesis and anti-gastric cancer evaluation
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2022, 卷号: 71
作者:
Li, Haobin
;
Cai, Maohua
;
Cao, Fei
;
Yu, Dehua
;
Yang, Jing
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2022/12/22
STAT3 inhibitor
Quinone derivative
S3I-201
Anti -gastric cancer drug
Epigallocatechin gallate-loaded tetrahedral DNA nanostructures as a novel inner ear drug delivery system
期刊论文
NANOSCALE, 2022, 卷号: 14
作者:
Chen, Yuming
;
Gu, Jiayi
;
Liu, Yan
;
Xu, Ke
;
Song, Jie
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2022/12/23
Design, synthesis and biological evaluation of sulfonamides inhibitors of XPO1 displaying activity against multiple myeloma cells
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 235
作者:
Qu, Bingxue
;
Xu, Yongjin
;
Lu, Yang
;
Zhuang, Weihao
;
Jin, Xinxin
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2022/12/23
XPO1
Multiple myeloma
MM.1S
N-phenylsulfonamide
Oral administration
Luteolin attenuated cisplatin-induced cardiac dysfunction and oxidative stress via modulation of Keap1/Nrf2 signaling pathway
期刊论文
FREE RADICAL RESEARCH, 2022
作者:
Qi, Yajun
;
Fu, Shuang
;
Pei, Donggen
;
Fang, Qilu
;
Xin, Wenxiu
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2022/12/23
Luteolin
cisplatin
oxidative stress
Keap1
Nrf2
CHMFL-26 is a highly potent irreversible HER2 inhibitor for use in the treatment of HER2-positive and HER2-mutant cancers
期刊论文
ACTA PHARMACOLOGICA SINICA, 2022
作者:
Cao, Jiang-yan
;
Qi, Shuang
;
Wu, Hong
;
Wang, Ao-li
;
Liu, Qing-wang
收藏
  |  
浏览/下载:92/0
  |  
提交时间:2022/03/28
HER2
breast cancers
gastric cancers
irreversible inhibitor
drug resistance
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