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上海药物研究所 [23]
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期刊论文 [34]
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Cocktail polysaccharides isolated from Ecklonia kurome against the SARS-CoV-2 infection
期刊论文
CARBOHYDRATE POLYMERS, 2022, 卷号: 275, 页码: 8
作者:
Zhang, Shihai
;
Pei, Rongjuan
;
Li, Meixia
;
Su, Haixia
;
Sun, Hao
收藏
  |  
浏览/下载:71/0
  |  
提交时间:2021/12/16
COVID-19
SARS-CoV-2
Angiotensin converting enzyme 2 (ACE2)
3CL protease
Ecklonia kurome Okam
Polysaccharide
Identification of pyrogallol as a warhead in design of covalent inhibitors for the SARS-CoV-2 3CL protease
期刊论文
NATURE COMMUNICATIONS, 2021, 卷号: 12, 期号: 1, 页码: 12
作者:
Su, Haixia
;
Yao, Sheng
;
Zhao, Wenfeng
;
Zhang, Yumin
;
Liu, Jia
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2021/08/17
What coronavirus 3C-like protease tells us: From structure, substrate selectivity, to inhibitor design
期刊论文
MEDICINAL RESEARCH REVIEWS, 2021, 页码: 34
作者:
Xiong, Muya
;
Su, Haixia
;
Zhao, Wenfeng
;
Xie, Hang
;
Shao, Qiang
收藏
  |  
浏览/下载:42/0
  |  
提交时间:2021/05/24
3C-like protease
binding modes
coronavirus
inhibitors
structure and function
Anti-SARS-CoV-2 activities in vitro of Shuanghuanglian preparations and bioactive ingredients
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 11
作者:
Su, Hai-xia
;
Yao, Sheng
;
Zhao, Wen-feng
;
Li, Min-jun
;
Liu, Jia
收藏
  |  
浏览/下载:115/0
  |  
提交时间:2020/12/24
SARS-CoV-2
3CL protease
traditional Chinese medicines
Shuanghuanglian oral liquid
baicalin
baicalein
Active constituents and mechanisms of Respiratory Detox Shot, a traditional Chinese medicine prescription, for COVID-19 control and prevention: Network -molecular docking-LC-MSE analysis
期刊论文
JOURNAL OF INTEGRATIVE MEDICINE-JIM, 2020, 卷号: 18, 期号: 3, 页码: 229-241
作者:
Zhang, Zi-jia
;
Wu, Wen-yong
;
Hou, Jin-jun
;
Zhang, Lin-lin
;
Li, Fei-fei
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  |  
浏览/下载:49/0
  |  
提交时间:2020/07/01
Lung-toxin Dispelling Formula No. 1
COVID-19
3C-like protease
Network pharmacology
Molecular docking
Meridian tropism
The search for a structural basis for therapeutic intervention against the SARS coronavirus
期刊论文
2010, 2010
Mark, Bartlam
;
Xue, Xiaoyu
;
Rao, Zihe
收藏
  |  
浏览/下载:4/0
Rapid peptide-based screening on the substrate specificity of severe acute respiratory syndrome (SARS) coronavirus 3C-like protease by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry
期刊论文
2010, 2010
Chu, LHM
;
Choy, WY
;
Tsai, SN
;
Rao, ZH
;
Ngai, SM
收藏
  |  
浏览/下载:3/0
Maturation Mechanism of Severe Acute Respiratory Syndrome (SARS) Coronavirus 3C-like Proteinase
期刊论文
journal of biological chemistry, 2010
Li, Chunmei
;
Qi, Yifei
;
Teng, Xin
;
Yang, Zongchang
;
Wei, Ping
;
Zhang, Changsheng
;
Tan, Lei
;
Zhou, Lu
;
Liu, Ying
;
Lai, Luhua
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  |  
浏览/下载:2/0
  |  
提交时间:2015/11/14
CRYSTAL-STRUCTURE
DIMER INTERFACE
SUBSTRATE-SPECIFICITY
HIV-1 PROTEASE
VIRUS
DIMERIZATION
INHIBITOR
DESIGN
DOMAIN
POLYPROTEIN
Two adjacent mutations on the dimer interface of SARS coronavirus 3C-like protease cause different conformational changes in crystal structure
期刊论文
VIROLOGY, 2009, 卷号: 388, 期号: 2, 页码: 324-334
作者:
Hu, Tiancen
;
Zhang, Yu
;
Li, Lianwei
;
Wang, Kuifeng
;
Chen, Shuai
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2019/01/08
SARS coronavirus
3C-like protease
Dimerization
Enzymatic activity
Mutation
Monomer
Two adjacent mutations on the dimer interface of SARS coronavirus 3C-like protease cause different conformational changes in crystal structure
期刊论文
VIROLOGY, 2009, 卷号: 388, 期号: 2, 页码: 324-334
作者:
Hu, TC
;
Zhang, Y
;
Li, LW
;
Wang, KF
;
Chen, S
收藏
  |  
浏览/下载:47/0
  |  
提交时间:2015/07/22
SARS coronavirus
3C-like protease
Dimerization
Enzymatic activity
Mutation
Monomer
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