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科研机构
山东大学 [65]
内容类型
期刊论文 [61]
会议论文 [4]
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2019 [6]
2018 [9]
2017 [3]
2016 [9]
2015 [7]
2014 [5]
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专题:山东大学
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Identification and structure-function analyses of an allosteric inhibitor of the tyrosine phosphatase PTPN22
期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2019, 卷号: 294, 期号: 21, 页码: 8653-8663
作者:
Li, Kangshuai
;
Hou, Xuben
;
Li, Ruirui
;
Bi, Wenxiang
;
Yang, Fan
收藏
  |  
浏览/下载:109/0
  |  
提交时间:2019/12/11
allosteric regulation
enzyme inhibitor
enzyme
inhibitor
nuclear
magnetic resonance (NMR)
autoimmunity
lymphoid-specific tyrosine
phosphatase (LYP)
protein-tyrosine phosphatase nonreceptor type 22
(PTPN22)
tyrosine phosphatase inhibitor
WPD-loop
Inhibitory effects of polyphyllins I and VII on human cisplatin-resistant NSCLC via p53 upregulation and CIP2A/AKT/mTOR signaling axis inhibition
期刊论文
CHINESE JOURNAL OF NATURAL MEDICINES, 2019, 卷号: 17, 期号: 10, 页码: 768-777
作者:
Feng Fei-Fei
;
Cheng Peng
;
Sun Chao
;
Wang Hui
;
Wang Wei
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2019/12/11
Polyphyllin I
Polyphyllin VII
Cisplatin-resistance
Non-small cell
lung cancer
p53
Cancerous inhibitor of protein phosphatase 2A
Prognostic value of dynamic albumin-to-alkaline phosphatase ratio in limited stage small-cell lung cancer
期刊论文
FUTURE ONCOLOGY, 2019, 卷号: 15, 期号: 9, 页码: 995-1006
作者:
Li, Xiaogang
;
Li, Butuo
;
Zeng, Haiyan
;
Wang, Shijiang
;
Sun, Xindong
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2019/12/11
albumin-to-alkaline phosphatase ratio
dynamically
limited stage
small-cell lung cancer
prognostic
survival analysis
Crystal structure and catalytic activity of the PPM1K N94K mutant
期刊论文
JOURNAL OF NEUROCHEMISTRY, 2019, 卷号: 148, 期号: 4, 页码: 550-560
作者:
Dolatabad, Meisam Rostaminasab
;
Guo, Lu-lu
;
Xiao, Peng
;
Zhu, Zhongliang
;
He, Qing-tao
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2019/12/11
active site
crystal structure
phosphatase activity
protein
phosphatase Mg2+/Mn2+-dependent 1K
single nucleotide polymorphisms
third metal ion
Tyrosine-protein phosphatase non-receptor type 2 inhibits alveolar bone resorption in diabetic periodontitis via dephosphorylating CSF1 receptor
期刊论文
Journal of Cellular and Molecular Medicine, 2019
作者:
Zhang D.
;
Jiang Y.
;
Song D.
;
Zhu Z.
;
Zhou C.
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2019/12/11
25(OH)2D3
alveolar bone resorption
CSF1R
diabetic periodontitis
tyrosine-protein phosphatase non-receptor type 2
Highly Selective Protein Tyrosine Phosphatase Inhibitor, 2,2 ',3,3 '-Tetrabromo-4,4 ',5,5 '-tetrahydroxydiphenylmethane, Ameliorates Type 2 Diabetes Mellitus in BKS db Mice
期刊论文
MOLECULAR PHARMACEUTICS, 2019, 卷号: 16, 期号: 5, 页码: 1839-1850
作者:
Li, Chao
;
Luo, Jiao
;
Guo, Shuju
;
Jia, Xiaoling
;
Guo, Chuanlong
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2019/12/11
type 2 diabetes mellitus
protein tyrosine phosphatase 1B
insulin
resistance
hypoglycemic activity
dyslipidemia
Allosteric modulation of the catalytic VYD loop in Slingshot by its N-terminal domain underlies both Slingshot auto-inhibition and activation
期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2018, 卷号: 293, 期号: 42, 页码: 16226-16241
作者:
Yang, Duxiao
;
Xiao, Peng
;
Li, Qing
;
Fu, Xiaolei
;
Pan, Chang
收藏
  |  
浏览/下载:44/0
  |  
提交时间:2019/12/11
actin
allosteric regulation
amino acid
biosensor
phosphatase
phosphorylation
serine
threonine protein kinase
cytoskeleton
assay
development
auto-inhibition
bioluminescence resonance energy transfer
fluorescein arsenical hairpin binder
Slingshot
actin activation
fluorescein arsenical hairpin binder
Effects of silencing the DUSP1 gene using lentiviral vector-mediated siRNA on the release of proinflammatory cytokines through regulation of the MAPK signaling pathway in mice with acute pancreatitis
期刊论文
INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE, 2018, 卷号: 41, 期号: 4, 页码: 2213-2224
作者:
Zhang, Bo
;
Li, Shu-Liang
;
Xie, Hua-Lei
;
Fan, Jia-Wei
;
Gu, Chuan-Wei
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2019/12/11
lentiviral vectors
dual specificity phosphatase 1
mitogen-activated
protein kinase signaling pathway
acute pancreatitis
proinflammatory
cytokines
high mobility group box 1
S100A12
PINK1 Protects Against Gentamicin-Induced Sensory Hair Cell Damage: Possible Relation to Induction of Autophagy and Inhibition of p53 Signal Pathway
期刊论文
FRONTIERS IN MOLECULAR NEUROSCIENCE, 2018, 卷号: 11
作者:
Yang, Qiandian
;
Zhou, Yiwei
;
Yin, Haiyan
;
Li, Hongrui
;
Zhou, Meijuan
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2019/12/11
phosphatase and tensin homolog (PTEN)-induced putative kinase 1 (PINK1)
gentamicin (GM)
ROS
autophagy
p53
PINK1 Protects Auditory Hair Cells and Spiral Ganglion Neurons from Cisplatin-induced Ototoxicity via Inducing Autophagy and Inhibiting JNK Signaling Pathway
期刊论文
FREE RADICAL BIOLOGY AND MEDICINE, 2018, 卷号: 120, 页码: 342-355
作者:
Yang, Qianqian
;
Sun, Gaoying
;
Yin, Haiyan
;
Li, Hongrui
;
Cao, Zhixin
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2019/12/11
Phosphatase and tensin homologue (PTEN)-induced putative kinase 1
(PINK1)
Cisplatin
ROS
Autophagy
Apoptosis
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