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期刊论文 [9]
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2020 [9]
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Disrupting phosphatase SHP2 in macrophages protects mice from high-fat diet-induced hepatic steatosis and insulin resistance by elevating IL-18 levels
期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2020, 卷号: 295, 期号: 31, 页码: 10842-10856
作者:
Liu, Wen
;
Yin, Ye
;
Wang, Meijing
;
Fan, Ting
;
Zhu, Yuyu
收藏
  |  
浏览/下载:219/0
  |  
提交时间:2020/12/24
Src homology 2 domain containing tyrosine phosphatase-2 (SHP2)
hepatic steatosis
insulin resistance
caspase-1
interleukin 18 (IL-18)
fatty liver
metabolic disorder
inflammation
cytokine signaling
caspase 1 (CASP1)
tyrosine-protein phosphatase (tyrosine phosphatase)
macrophage
Deep Learning Based Drug Screening for Novel Coronavirus 2019-nCov
期刊论文
INTERDISCIPLINARY SCIENCES-COMPUTATIONAL LIFE SCIENCES, 2020, 页码: 9
作者:
Zhang, Haiping
;
Saravanan, Konda Mani
;
Yang, Yang
;
Hossain, Md Tofazzal
;
Li, Junxin
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  |  
浏览/下载:199/0
  |  
提交时间:2020/12/10
Coronavirus
Deep learning
Drug screening
Homology modeling
3C-like protease
The Grassmannian of affine subspaces
期刊论文
FOUNDATIONS OF COMPUTATIONAL MATHEMATICS, 2020, 页码: 38
作者:
Lim, Lek-Heng
;
Wong, Ken Sze-Wai
;
Ye, Ke
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  |  
浏览/下载:251/0
  |  
提交时间:2020/06/30
Affine Grassmannian
Affine subspaces
Schubert calculus
homotopy and (co)homology
Probability densities
Distances and metrics
Multivariate data analysis
Synthesis, antifungal activity and potential mechanism of fusidic acid derivatives possessing amino-terminal groups
期刊论文
FUTURE MEDICINAL CHEMISTRY, 2020, 卷号: 12, 期号: 9, 页码: 763-774
作者:
Cao, Yucheng
;
Ni, Jingxuan
;
Ji, Wentao
;
Shang, Kangle
;
Liang, Kaicheng
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  |  
浏览/下载:13/0
  |  
提交时间:2020/12/24
antifungal activity
fusidic acid
homology modeling
molecular docking
molecular dynamics simulations
Discovery of a potent and selective adenylyl cyclase type 8 agonist by docking-based virtual screening
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2020, 卷号: 30, 期号: 2, 页码: 7
作者:
Weng, Zhiying
;
Xu, Guowei
;
Chen, Dingyuan
;
Yang, Yaqing
;
Song, Gao
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2020/03/18
Adenylyl cyclases
Homology modeling
Consensus scoring
Molecular dynamics simulation
Virtual screening
Biological evaluation
Fossils from South China redefine the ancestral euarthropod body plan
期刊论文
BMC EVOLUTIONARY BIOLOGY, 2020, 卷号: 20, 期号: 1, 页码: 17
作者:
Aria, Cedric
;
Zhao, Fangchen (赵方臣)
;
Zeng, Han (曾晗)
;
Guo, Jin
;
Zhu, Maoyan (朱茂炎)
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  |  
浏览/下载:3/0
  |  
提交时间:2020/04/03
Euarthropoda
Body plan
Cambrian
Chengjiang
Macroevolution
Homology
Simulative structure and binding sites of lyral with olfactory receptor 10J5 using computational prediction methods
期刊论文
JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART A-CURRENT ISSUES, 2020, 卷号: 83, 期号: 1, 页码: 1-8
作者:
Wang, P (Wang, Pu)[ 1 ]
;
Zhang, R (Zhang, Rui)[ 2,3 ]
;
Yu, SB (Yu, Shunbang)[ 1 ]
;
Lee, C (Lee, Charles)[ 4 ]
;
Wang, H (Wang, He)[ 1 ]
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  |  
浏览/下载:27/0
  |  
提交时间:2020/03/16
Homology modeling
ligand docking
binding sites
olfactory receptor
lyral
A Collinearity-Incorporating Homology Inference Strategy for Connecting Emerging Assemblies in the Triticeae Tribe as a Pilot Practice in the Plant Pangenomic Era
期刊论文
MOLECULAR PLANT, 2020, 卷号: 13, 期号: 12, 页码: 1694-1708
作者:
Chen, Yongming
;
Song, Wanjun
;
Xie, Xiaoming
;
Wang, Zihao
;
Guan, Panfeng
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2022/03/01
homology inference
collinearity
database
pangenome
Triticeae tribe
polyploid
In silico identification and structure function analysis of a putative coclaurine N-methyltransferase from Aristolochia fimbriata
期刊论文
COMPUTATIONAL BIOLOGY AND CHEMISTRY, 2020, 卷号: 85
作者:
Ali, Roshan
;
Jiao, Yuannian
;
Wall, P. Kerr
;
Patching, Simon G.
;
Ahmad, Irshad
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2022/03/01
Coclaurine N-methyltransferase
Aristolochia fimbriata
Basal angiosperm
Aristolochic acid
Reaction mechanism
Homology model
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