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Effective Virtual Screening Strategy toward heme-containing proteins: Identification of novel IDO1 inhibitors
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 184, 页码: 23
作者:
Zou, Yi
;
Hu, Yue
;
Ge, Shushan
;
Zheng, Yingbo
;
Li, Yuezhen
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2020/07/01
IDO1
Heme
T cell
Cancer immunotherapy
Virtual screening
Drug design
Molecular dynamics simulation
Design, synthesis and biological evaluation of novel copper-chelating acetylcholinesterase inhibitors with pyridine and N-benzylpiperidine fragments
期刊论文
BIOORGANIC CHEMISTRY, 2019, 卷号: 93, 页码: 13
作者:
Zhou, Yeheng
;
Sun, Wei
;
Peng, Jiale
;
Yan, Hui
;
Zhang, Li
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2020/03/18
Acetylcholinesterase
Drug design
N-acylhydrazone
Dementia
Copper-chelating
N-Benzylpiperidine
Parallel Adaptive Critic Designs of Optimal Control for Ice-Storage Air Conditioning Systems
会议论文
Xiamen, China, 2019-12
作者:
Liao, Zehua
;
Wei, Qinglai
;
Song, Ruizhuo
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2020/06/26
Parallel adaptive critic design
Adaptive dynamic programming
Particle swarm optimization
Ice-storage air conditioning
Proposed Green Development Reporting Framework for Enterprises from a Life-Cycle Perspective and a Case Study in China
期刊论文
SUSTAINABILITY, 2019, 卷号: 11, 期号: 23, 页码: -
作者:
Ding, Ning
;
Ruan, Xinhui
;
Yang, Jianxin
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2020/09/09
enterprise
green development
life-cycle assessment
green design
green products
Fire resistance of thin-walled tubular T-joints with internal ring stiffeners under post-earthquake fire
期刊论文
Thin-Walled Structures, 2019, 卷号: 145
作者:
Xu, Jixiang
;
Tong, Yige
;
Han, Jianping
;
Han, Zhaolong
;
Li, Zhanjie
收藏
  |  
浏览/下载:0/0
  |  
提交时间:2022/02/17
Computation theory
Computational methods
Earthquakes
Failure modes
Rings (components)
Thin walled structures
Tubular steel structures
Critical temperatures
Design recommendations
Diameter-thickness ratio
Influencing parameters
Internal ring stiffeners
Post-earthquake fires
Resistance behaviors
Tubular T joints
Analysis of shear stress distribution at the anchorage interface of rock slope and its influencing factors under seismic action
期刊论文
Zhendong Gongcheng Xuebao/Journal of Vibration Engineering, 2019, 卷号: 32, 期号: 6, 页码: 1029-1040
作者:
Yan, Zhi-Xin
;
Long, Zhe
;
Zhang, Sen
;
Zhou, Xiao-Liang
;
Dong, Jian-Hua
收藏
  |  
浏览/下载:0/0
  |  
提交时间:2022/02/17
Anchor bolts
Anchorages (foundations)
Bolts
Earthquakes
Joints (structural components)
Mortar
Numerical methods
Rocks
Seismic waves
Shear flow
Stress concentration
Anchoring
Bedding rock slope
Design and construction
Ground motion parameters
Influencing factor
Interface shear stress
Numerical analysis models
Rock slope
Research on Numerical Modeling Method for Rocking Self-Centering Bridge Piers
期刊论文
Yingyong Jichu yu Gongcheng Kexue Xuebao/Journal of Basic Science and Engineering, 2019, 卷号: 27, 期号: 6, 页码: 1357-1369
作者:
Sun, Zhiguo
;
Zhao, Taiyi
;
Shi, Yan
;
Wang, Dongsheng
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2020/11/14
Bridge piers
Constitutive models
Hysteresis
Numerical analysis
Numerical methods
Seismic design
Seismic response
Springs (components)
Stiffness
Tendons
Concrete constitutive models
Double column bridge
Fiber beam-column elements
Numerical analysis models
Numerical modeling method
Seismic behavior
Self centering
Simulation accuracy
Fire resistance of thin-walled tubular T-joints with internal ring stiffeners under post-earthquake fire
期刊论文
Thin-Walled Structures, 2019, 卷号: 145
作者:
Xu, Jixiang
;
Tong, Yige
;
Han, Jianping
;
Han, Zhaolong
;
Li, Zhanjie
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2020/11/14
Computation theory
Computational methods
Earthquakes
Failure modes
Rings (components)
Thin walled structures
Tubular steel structures
Critical temperatures
Design recommendations
Diameter-thickness ratio
Influencing parameters
Internal ring stiffeners
Post-earthquake fires
Resistance behaviors
Tubular T joints
Analysis of shear stress distribution at the anchorage interface of rock slope and its influencing factors under seismic action
期刊论文
Zhendong Gongcheng Xuebao/Journal of Vibration Engineering, 2019, 卷号: 32, 期号: 6, 页码: 1029-1040
作者:
Yan, Zhi-Xin
;
Long, Zhe
;
Zhang, Sen
;
Zhou, Xiao-Liang
;
Dong, Jian-Hua
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2020/11/14
Anchor bolts
Anchorages (foundations)
Bolts
Earthquakes
Joints (structural components)
Mortar
Numerical methods
Rocks
Seismic waves
Shear flow
Stress concentration
Anchoring
Bedding rock slope
Design and construction
Ground motion parameters
Influencing factor
Interface shear stress
Numerical analysis models
Rock slope
Mechanical Design and Testing of the Magnet Mirror Structure for Dummy Coil of a Superconducting FECR Ion Source
期刊论文
Xiyou Jinshu Cailiao Yu Gongcheng/Rare Metal Materials and Engineering, 2019, 卷号: 48, 期号: 12, 页码: 4035-4038
作者:
Zhu, Li
;
Wu, Wei
;
Yu, Shurong
;
Du, Zhuoyue
;
Chen, Yuquan
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2020/11/14
Binary alloys
Ion sources
Magnets
Mirrors
Niobium alloys
Software testing
Strain
Superconducting coils
Superconducting magnets
Tin alloys
ANSYS
Dummy coil
Key technologies
Magnet assembly
Mechanical design
Mirror structure
Nb3Sn
Vacuum impregnation
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