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Exploring binding mechanisms of VEGFR2 with three drugs lenvatinib, sorafenib, and sunitinib by molecular dynamics simulation and free energy calculation 期刊论文
CHEMICAL BIOLOGY & DRUG DESIGN, 2019, 卷号: 93, 期号: 5, 页码: 934-948
作者:  Wang, Yu;  Peng, Cheng;  Wang, Guimin;  Xu, Zhijian;  Luo, Yongfeng
收藏  |  浏览/下载:18/0  |  提交时间:2020/07/01
Identification of recurrent USP48 and BRAF mutations in Cushing's disease 期刊论文
NATURE COMMUNICATIONS, 2018, 卷号: 9
作者:  Chen, Jianhua;  Jian, Xuemin;  Deng, Siyu;  Ma, Zengyi;  Shou, Xuefei
收藏  |  浏览/下载:118/0  |  提交时间:2019/01/08
Bavachinin, as a novel natural pan-PPAR agonist, exhibits unique synergistic effects with synthetic PPAR-gamma and PPAR-alpha agonists on carbohydrate and lipid metabolism in db/db and diet-induced obese mice 期刊论文
DIABETOLOGIA, 2016, 卷号: 59, 期号: 6, 页码: 1276-1286
作者:  Feng, Li;  Luo, Huan;  Xu, Zhijian;  Yang, Zhuo;  Du, Guoxin
收藏  |  浏览/下载:48/0  |  提交时间:2019/01/08
Thermodynamic and Structural Characterization of Halogen Bonding in Protein-Ligand Interactions: A Case Study of PDE5 and Its Inhibitors 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2014, 卷号: 57, 期号: 8, 页码: 3588-3593
作者:  Ren, Jing;  He, Yang;  Chen, Wuyan;  Chen, Tiantian;  Wang, Guan
收藏  |  浏览/下载:21/0  |  提交时间:2019/01/08
Combining pharmacophore, docking and substructure search approaches to identify and optimize novel B-Raf(V600E) inhibitors 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2012, 卷号: 22, 期号: 17, 页码: 5428-5437
作者:  Xu, Zhijian;  Yan, Guirui;  Wang, Gaihong;  Li, Bo;  Zhu, Jianming
收藏  |  浏览/下载:11/0  |  提交时间:2019/01/08
Why are oseltamivir and zanamivir effective against the newly emerged influenza A virus (A/H1N1)? 期刊论文
CELL RESEARCH, 2009, 卷号: 19, 期号: 10, 页码: 1221-1224
作者:  Yu, Kunqian;  Luo, Cheng;  Qin, Guangrong;  Xu, Zhijian;  Li, Ning
收藏  |  浏览/下载:11/0  |  提交时间:2019/01/08
C-X center dot center dot center dot H Contacts in Biomolecular Systems: How They Contribute to Protein-Ligand Binding Affinity 期刊论文
JOURNAL OF PHYSICAL CHEMISTRY B, 2009, 卷号: 113, 期号: 37, 页码: 12615-12621
作者:  Lu, Yunxiang;  Wang, Yong;  Xu, Zhijian;  Yan, Xiuhua;  Luo, Xiaoming
收藏  |  浏览/下载:17/0  |  提交时间:2019/01/08


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