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CORC

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Pharmacodynamic, pharmacokinetic, and phase 1a study of bisthianostat, a novel histone deacetylase inhibitor, for the treatment of relapsed or refractory multiple myeloma 期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 9
作者:  Zhou, Yu-bo;  Zhang, Yang-ming;  Huang, Hong-hui;  Shen, Li-jing;  Han, Xiao-feng
收藏  |  浏览/下载：93/0  |  提交时间：2021/11/04
Pharmacokinetics-based identification of pseudoaldosterogenic compounds originating from Glycyrrhiza uralensis roots (Gancao) after dosing LianhuaQingwen capsule 期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 18
作者:  Lan, Xiao-fang;  Olaleye, Olajide E.;  Lu, Jun-lan;  Yang, Wei;  Du, Fei-fei
收藏  |  浏览/下载：75/0  |  提交时间：2021/06/11
A 36-week multicenter, randomized, double-blind, placebo-controlled, parallel-group, phase 3 clinical trial of sodium oligomannate for mild-to-moderate Alzheimer’s dementia 期刊论文
Alzheimer's Research & Therapy, 2021, 卷号: 13, 期号: 1
作者:  Xiao,Shifu;  Chan,Piu;  Wang,Tao;  Hong,Zhen;  Wang,Shuzhen
收藏  |  浏览/下载：148/0  |  提交时间：2021/05/24
AMPK activator C24 inhibits hepatic lipogenesis and ameliorates dyslipidemia in HFHC diet-induced animal models 期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 8
作者:  Sun, Shui-mei;  Xie, Zhi-fu;  Zhang, Yang-ming;  Zhang, Xin-wen;  Zhou, Chen-dong
收藏  |  浏览/下载：25/0  |  提交时间：2020/12/24
Synthesis and in Vitro and in Vivo Biological Evaluation of Tissue-Specific Bisthiazole Histone Deacetylase (HDAC) Inhibitors 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 63, 期号: 2, 页码: 804-815
作者:  Zhang, Shu-Wei;  Gong, Chao-Jun;  Su, Ming-Bo;  Chen, Fei;  He, Ting
收藏  |  浏览/下载：10/0  |  提交时间：2020/07/01
Novel substituted pyrazolone derivatives as AMP-activated protein kinase activators to inhibit lipid synthesis and reduce lipid accumulation in ob/ob mice 期刊论文
ACTA PHARMACOLOGICA SINICA, 2018, 卷号: 39, 期号: 10, 页码: 1622-1632
作者:  Zhang, Mei;  Xie, Zhi-fu;  Zhang, Run-tao;  Chen, Da-kai;  Gu, Min
收藏  |  浏览/下载：43/0  |  提交时间：2019/01/08
Transgelin-2 as a therapeutic target for asthmatic pulmonary resistance 期刊论文
SCIENCE TRANSLATIONAL MEDICINE, 2018, 卷号: 10, 期号: 427
作者:  Yin, Lei-Miao;  Xu, Yu-Dong;  Peng, Ling-Ling;  Duan, Ting-Ting;  Liu, Jia-Yuan
收藏  |  浏览/下载：34/0  |  提交时间：2019/01/08
白血病抑制因子受体反馈上调介导乳腺癌对组蛋白去乙酰化酶抑制剂耐药 期刊论文
科学新闻, 2017, 期号: 04, 页码: 58
作者:  Hanlin Zeng;  Jia Qu;  Nan Jin;  Jun Xu;  Chenchu Lin
收藏  |  浏览/下载：23/0  |  提交时间：2019/01/08
Feedback Activation of Leukemia Inhibitory Factor Receptor Limits Response to Histone Deacetylase Inhibitors in Breast Cancer 期刊论文
CANCER CELL, 2016, 卷号: 30, 期号: 3, 页码: 459-473
作者:  Zeng, Hanlin;  Qu, Jia;  Jin, Nan;  Xu, Jun;  Lin, Chenchu
收藏  |  浏览/下载：23/0  |  提交时间：2019/01/08
Design, synthesis and biological evaluation of bisthiazole-based trifluoromethyl ketone derivatives as potent HDAC inhibitors with improved cellular efficacy 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2016, 卷号: 112, 页码: 81-90
作者:  Gong, Chao-Jun;  Gao, An-Hui;  Zhang, Yang-Ming;  Su, Ming-Bo;  Chen, Fei
收藏  |  浏览/下载：22/0  |  提交时间：2019/01/08

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