CORC

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CORC

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Inhibition of Autophagy by a Small Molecule through Covalent Modification of the LC3 Protein 期刊论文
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2021, 页码: 11
作者:  Fan, Shijie;  Yue, Liyan;  Wan, Wei;  Zhang, Yuanyuan;  Zhang, Bidong
收藏  |  浏览/下载：80/0  |  提交时间：2021/12/16
Discovery of an M-Substituted N-Cyclopropylmethyl-7 alpha-phenyl-6,14-endoethanotetrahydronorthebaine as a Selective, Potent, and Orally Active kappa-Opioid Receptor Agonist with an Improved Central Nervous System Safety Profile 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 16, 页码: 12414-12433
作者:  He, Qian;  Wei, Yuanyuan;  Liu, Xiao;  Ye, Rongrong;  Kong, Linghui
收藏  |  浏览/下载：88/0  |  提交时间：2021/11/04
Structure-Guided Development of Small-Molecule PRC2 Inhibitors Targeting EZH2-EED Interaction 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 12, 页码: 8194-8207
作者:  Du, Daohai;  Xu, Dandan;  Zhu, Licheng;  Stazi, Giulia;  Zwergel, Clemens
收藏  |  浏览/下载：74/0  |  提交时间：2021/08/17
Exploration of the SAR Connection between Morphinan- and Arylacetamide-Based kappa Opioid Receptor (kappa OR) Agonists Using the Strategy of Bridging 期刊论文
ACS CHEMICAL NEUROSCIENCE, 2021, 卷号: 12, 期号: 6, 页码: 1018-1030
作者:  Liu, Xiao;  Jiang, Shuang;  Kong, Linghui;  Ye, Rongrong;  Xiao, Li
收藏  |  浏览/下载：114/0  |  提交时间：2021/05/24
PRMT1 is a novel molecular therapeutic target for clear cell renal cell carcinoma 期刊论文
THERANOSTICS, 2021, 卷号: 11, 期号: 11, 页码: 5387-5403
作者:  Wang, Jianfeng;  Wang, Chen;  Xu, Pan;  Li, Xiao;  Lu, Yongning
收藏  |  浏览/下载：130/0  |  提交时间：2021/05/24
An Integrated LC-MS/MS Strategy for Quantifying the Oxidative-Redox Metabolome in Multiple Biological Samples 期刊论文
ANALYTICAL CHEMISTRY, 2020, 卷号: 92, 期号: 13, 页码: 8810-8818
作者:  Liu, Huiying;  Xu, Feng;  Gao, Yuqing;  Pang, Yuanyuan;  Xie, Cen
收藏  |  浏览/下载：62/0  |  提交时间：2020/12/24
Covalent Inhibitors Allosterically Block the Activation of Rho Family Proteins and Suppress Cancer Cell Invasion 期刊论文
ADVANCED SCIENCE, 2020, 页码: 13
作者:  Sun, Zhongya;  Zhang, Hao;  Zhang, Yuanyuan;  Liao, Liping;  Zhou, Wen
收藏  |  浏览/下载：107/0  |  提交时间：2020/07/01
Interfering MSN-NONO complex-activated CREB signaling serves as a therapeutic strategy for triple-negative breast cancer 期刊论文
SCIENCE ADVANCES, 2020, 卷号: 6, 期号: 8, 页码: 13
作者:  Qin, Yuanyuan;  Chen, Weilong;  Jiang, Guojuan;  Zhou, Lei;  Yang, Xiaoli
收藏  |  浏览/下载：78/0  |  提交时间：2020/07/01
Discovery of a Highly Selective and Potent kappa Opioid Receptor Agonist from N-Cyclopropylmethyl-7 alpha-phenyl-6,14-endoethanotetrahydronorthebaines with Reduced Central Nervous System (CNS) Side Effects Navigated by the Message-Address Concept 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 24, 页码: 11054-11070
作者:  Xiao, Li;  Wang, Yujun;  Zhang, Mumei;  Wu, Weiwei;  Kong, Linghui
收藏  |  浏览/下载：93/0  |  提交时间：2020/07/01
Discovery and biological evaluation of vinylsulfonamide derivatives as highly potent, covalent TEAD autopalmitoylation inhibitors 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 184, 页码: 15
作者:  Lu, Wenchao;  Wang, Jun;  Li, Yong;  Tao, Hongru;  Xiong, Huan
收藏  |  浏览/下载：94/0  |  提交时间：2020/07/01

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