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浏览/检索结果: 共32条，第1-10条 帮助 限定条件 发表日期：2021    专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 A general strategy to the intracellular sensing of glycosidases using AIE-based glycoclusters 期刊论文 CHEMICAL SCIENCE, 2021, 卷号: 13, 期号: 1, 页码: 247-256 作者:  Dong, Lei;  Zhang, Min-Yu;  Han, Hai-Hao;  Zang, Yi;  Chen, Guo-Rong 收藏  |  浏览/下载：31/0  |  提交时间：2022/01/18 Synthesis of the analogs of plocabulin and their preliminary structure-activity relationship study 期刊论文 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2021, 卷号: 51, 页码: 5 作者:  Wang, Leiming;  Li, Xin;  Cui, Hong;  Lei, Xinsheng;  Liu, Hongchun 收藏  |  浏览/下载：30/0  |  提交时间：2021/12/01 Marine nature products  Plocabulin  PM060184  Synthesis  Antiproliferation   Two New Cytotoxic Maytansinoids Targeting Tubulin from Trewia nudiflora 期刊论文 PLANTA MEDICA, 2021, 页码: 7 作者:  Lei, Chun;  Li, Ya-Nan;  Li, Jia-Nan;  Zhou, Yu-Bo;  Cui, Ming-Jun 收藏  |  浏览/下载：21/0  |  提交时间：2021/12/16 Trewia nudiflora  Euphorbiaceae  maytansinoids  cytotoxicity  tubulin polymerization   Discovery and Development of a Potent, Selective, and Orally Bioavailable CHK1 Inhibitor Candidate: 5-((4-((3-Amino-3-methylbutyl)amino)-5-(trifluoromethyl)pyrimidin-2-yl)amino)picolinonitrile 期刊论文 JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 20, 页码: 15069-15090 作者:  Jin, Tingting;  Xu, Lei;  Wang, Peipei;  Hu, Xiaobei;  Zhang, Runyuan 收藏  |  浏览/下载：23/0  |  提交时间：2022/01/04 Two New Oleanane-Triterpenoid Saponins from Clinopodium gracile 期刊论文 CHEMISTRY & BIODIVERSITY, 2021, 页码: 8 作者:  Zhao, Ting;  Liu, Yi-Nan;  Sun, Xin-Yu;  Li, Jing-Ya;  Lei, Chun 收藏  |  浏览/下载：18/0  |  提交时间：2021/12/01 Clinopodium gracile  Lamiaceae  triterpenoid saponins  oleanane   DRAK2 aggravates nonalcoholic fatty liver disease progression through SRSF6-associated RNA alternative splicing 期刊论文 CELL METABOLISM, 2021, 卷号: 33, 期号: 10, 页码: 2004-+ 作者:  Li, Yufeng;  Xu, Junyu;  Lu, Yuting;  Bian, Hua;  Yang, Lin 收藏  |  浏览/下载：23/0  |  提交时间：2022/01/18 Synthesis and Evaluation of 3-(Indol-3-yl)-4-(Pyrazolo[3,4-c]Pyridazin-3-yl)-Maleimides as Potent Mutant Isocitrate Dehydrogenase-1 Inhibitors 期刊论文 PHARMACEUTICAL CHEMISTRY JOURNAL, 2021, 卷号: 55, 期号: 7, 页码: 655-664 作者:  Xu, Jianghong;  Hu, Yuanyuan;  Liu, Xiaoqi 收藏  |  浏览/下载：37/0  |  提交时间：2021/12/01 IDH1-R132H inhibitors  synthesis  biological activity  docking  3-(indol-3-yl)-4-(pyrazolo-[3  4-c]pyridazin-3-yl)-maleimides   Discovery of a Potential Liver Fibrosis Inhibitor from a Mushroom Endophytic Fungus by Genome Mining of a Silent Biosynthetic Gene Cluster 期刊论文 JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2021, 卷号: 69, 期号: 38, 页码: 11303-11310 作者:  Cheng, Jin-Tao;  Wang, Han-Min;  Yu, Jia-Hui;  Sun, Chen-Fan;  Cao, Fei 收藏  |  浏览/下载：28/0  |  提交时间：2021/12/01 fungus  Calcarisporium arbuscula  natural product  gene cluster activation  liver fibrosis   Polyprenylated acylphloroglucinol meroterpenoids with PTP1B inhibition from Hypericum forrestii 期刊论文 FITOTERAPIA, 2021, 卷号: 153, 页码: 5 作者:  Zong, Jian-Fa;  Zhang, Meng-Meng;  Zhou, Yu-Bo;  Li, Jia;  Hou, Ai-Jun 收藏  |  浏览/下载：64/0  |  提交时间：2021/11/04 Hypericum forrestii (Chittenden) N Robson  Clusiaceae  Acylphloroglucinol meroterpenoid  Hyperiforins A-C  Protein tyrosine phosphatase 1B   Restoring perturbed oxylipins with Danqi Tongmai Tablet attenuates acute myocardial infarction 期刊论文 PHYTOMEDICINE, 2021, 卷号: 90, 页码: 12 作者:  Zhi, Haijuan;  Zhang, Zijia;  Deng, Yanping;  Yan, Bingpeng;  Li, Zhenwei 收藏  |  浏览/下载：48/0  |  提交时间：2021/11/04 Acute myocardial infarction  Danqi Tongmai tablet  In vivo metabolite  Oxylipin  Arachidonic acid metabolome  Homeostasis