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科研机构
上海药物研究所 [12]
内容类型
期刊论文 [12]
发表日期
2021 [12]
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浏览/检索结果:
共12条,第1-10条
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发表日期:2021
专题:上海药物研究所
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LS-106, a novel EGFR inhibitor targeting C797S, exhibits antitumor activities both in vitro and in vivo
期刊论文
CANCER SCIENCE, 2021, 页码: 12
作者:
Liu, Yingqiang
;
Lai, Mengzhen
;
Li, Shan
;
Wang, Yanan
;
Feng, Fang
收藏
  |  
浏览/下载:62/0
  |  
提交时间:2022/01/18
C797S
epidermal growth factor receptor
fourth-generation EGFR TKI
non-small cell lung cancer
osimertinib resistance
STING inhibitor ameliorates LPS-induced ALI by preventing vascular endothelial cells-mediated immune cells chemotaxis and adhesion
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 12
作者:
Wu, Bing
;
Xu, Meng-meng
;
Fan, Chen
;
Feng, Chun-lan
;
Lu, Qiu-kai
收藏
  |  
浏览/下载:59/0
  |  
提交时间:2022/01/18
acute lung injury
STING
vascular endothelial cells
inflammatory cytokines
chemokines
chemotaxis
Effect of autoinduction and food on the pharmacokinetics of furmonertinib and its active metabolite characterized by a population pharmacokinetic model
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 10
作者:
Zou, Hui-xi
;
Zhang, Yu-feng
;
Zhong, Da-fang
;
Jiang, Yong
;
Liu, Fei
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2022/01/04
furmonertinib
autoinduction
food effect
alkaline phosphatase
body weight
pharmacokinetics
modeling and simulation
NSCLC
Discovery of a subtype-selective, covalent inhibitor against palmitoylation pocket of TEAD3
期刊论文
ACTA PHARMACEUTICA SINICA B, 2021, 卷号: 11, 期号: 10, 页码: 3206-3219
作者:
Lu, Tian
;
Li, Yong
;
Lu, Wenchao
;
Spitters, Twgm
;
Fang, Xueyu
收藏
  |  
浏览/下载:41/0
  |  
提交时间:2021/12/01
Hippo pathway
TEAD3
Covalent inhibitor
Palmitoylation inhibitor
Acmoxanthones A-E, New Lavandulated Xanthones from Hypericum acmosepalum N. Robson
期刊论文
FITOTERAPIA, 2021, 卷号: 154, 页码: 5
作者:
Wang, Ai-Zhu
;
Fang, Qiang-Qiang
;
Feng, Tong-Tong
;
Wei, Ren-Jie
;
Jiang, Kun
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2021/12/01
Hypericum acmosepalum
Clusiaceae
Xanthones
Antioxidant
Cytotoxicity
Discovery of a novel third-generation EGFR inhibitor and identification of a potential combination strategy to overcome resistance (vol 19, 90, 2020)
期刊论文
MOLECULAR CANCER, 2021, 卷号: 20, 期号: 1, 页码: 1
作者:
Zhang, Tao
;
Qu, Rong
;
Chan, Shingpan
;
Lai, Mengzhen
;
Tong, Linjiang
收藏
  |  
浏览/下载:58/0
  |  
提交时间:2021/11/04
Correction to: Discovery of a novel third-generation EGFR inhibitor and identification of a potential combination strategy to overcome resistance
期刊论文
Molecular Cancer, 2021, 卷号: 20, 期号: 1
作者:
Zhang,Tao
;
Qu,Rong
;
Chan,Shingpan
;
Lai,Mengzhen
;
Tong,Linjiang
收藏
  |  
浏览/下载:41/0
  |  
提交时间:2021/11/04
Structurally diverse polyprenylated acylphloroglucinols from Hypericum uralum Buch.-Ham. ex D. Don
期刊论文
PHYTOCHEMISTRY, 2021, 卷号: 187, 页码: 7
作者:
Fang, Qiang-Qiang
;
Feng, Tong-Tong
;
Wang, Ai-Zhu
;
He, Wan-Ying
;
Wei, Ren-Jie
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2021/08/17
PPAPs
Hypericum uralum
Clusiaceae
Antioxidant
Cytotoxicity
SARS-CoV-2 envelope protein causes acute respiratory distress syndrome (ARDS)-like pathological damages and constitutes an antiviral target
期刊论文
CELL RESEARCH, 2021, 页码: 14
作者:
Xia, Bingqing
;
Shen, Xurui
;
He, Yang
;
Pan, Xiaoyan
;
Liu, Feng-Liang
收藏
  |  
浏览/下载:78/0
  |  
提交时间:2021/08/17
Heme supplementation ameliorates lupus nephritis through rectifying the disorder of splenocytes and alleviating renal inflammation and oxidative damage
期刊论文
INTERNATIONAL IMMUNOPHARMACOLOGY, 2021, 卷号: 94, 页码: 11
作者:
Wu, Bing
;
Wu, Yanwei
;
Fan, Chen
;
Feng, Chunlan
;
Wang, Haoyu
收藏
  |  
浏览/下载:50/0
  |  
提交时间:2021/06/11
SLE
Lupus nephritis
Heme
Inflammation
Oxidative damage
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