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浏览/检索结果: 共11条，第1-10条 帮助 限定条件 发表日期：2021    专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 Inhibition of Autophagy by a Small Molecule through Covalent Modification of the LC3 Protein 期刊论文 ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2021, 页码: 11 作者:  Fan, Shijie;  Yue, Liyan;  Wan, Wei;  Zhang, Yuanyuan;  Zhang, Bidong 收藏  |  浏览/下载：80/0  |  提交时间：2021/12/16 covalent modification  probes  proteome  LC3  post-translational modification   Nuclear UHRF1 is a gate-keeper of cellular AMPK activity and function 期刊论文 CELL RESEARCH, 2021, 页码: 18 作者:  Xu, Xiang;  Ding, Guangjin;  Liu, Caizhi;  Ding, Yuhan;  Chen, Xiaoxin 收藏  |  浏览/下载：63/0  |  提交时间：2021/11/04 Identification of novel anti-inflammatory Nur77 modulators by virtual screening 期刊论文 BIOORGANIC CHEMISTRY, 2021, 卷号: 112, 页码: 7 作者:  Ding, Xiaoyu;  Zhao, Zijie;  Wu, Yue;  Zhang, Hao;  Chen, Kaixian 收藏  |  浏览/下载：46/0  |  提交时间：2021/08/17 Nur77  Binding site evaluation  Virtual Screening  Inflammation   Structure-Guided Development of Small-Molecule PRC2 Inhibitors Targeting EZH2-EED Interaction 期刊论文 JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 12, 页码: 8194-8207 作者:  Du, Daohai;  Xu, Dandan;  Zhu, Licheng;  Stazi, Giulia;  Zwergel, Clemens 收藏  |  浏览/下载：74/0  |  提交时间：2021/08/17 Discovery of novel reversible monoacylglycerol lipase inhibitors via docking-based virtual screening 期刊论文 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2021, 卷号: 41, 页码: 6 作者:  Xiong, Fengmin;  Ding, Xiaoyu;  Zhang, Hao;  Luo, Xiaomin;  Chen, Kaixian 收藏  |  浏览/下载：24/0  |  提交时间：2021/08/17 Monoacylglycerol lipase  Inhibitor  Virtual screening  Inflammation   Discovery of novel ceramide analogs with favorable pharmacokinetic properties and combination with AKT inhibitor against colon cancer 期刊论文 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 215, 页码: 13 作者:  Gao, Feng;  Chen, Xiaoxu;  Lu, Junyan;  Hu, Shulei;  Xu, Hui 收藏  |  浏览/下载：42/0  |  提交时间：2021/05/24 Ceramide analogs  AKT inhibitor  MK2206  Colon cancer  Combination therapy   Engineering Oxaliplatin Prodrug Nanoparticles for Second Near-Infrared Fluorescence Imaging-Guided Immunotherapy of Colorectal Cancer 期刊论文 SMALL, 2021, 卷号: 17, 期号: 13, 页码: 11 作者:  Zhu, Qiurong;  Sun, Fang;  Li, Tianliang;  Zhou, Mengxue;  Ye, Jiayi 收藏  |  浏览/下载：108/0  |  提交时间：2021/05/24 colorectal cancer  combinatory immunotherapy  immunogenic cell death  prodrug nanoparticles  second near‐  infrared fluorescence imaging   A 36-week multicenter, randomized, double-blind, placebo-controlled, parallel-group, phase 3 clinical trial of sodium oligomannate for mild-to-moderate Alzheimer’s dementia 期刊论文 Alzheimer's Research & Therapy, 2021, 卷号: 13, 期号: 1 作者:  Xiao,Shifu;  Chan,Piu;  Wang,Tao;  Hong,Zhen;  Wang,Shuzhen 收藏  |  浏览/下载：147/0  |  提交时间：2021/05/24 Sodium oligomannate  Efficacy  Safety  Alzheimer’s disease  Clinical trial   Adaptive resistance to PI3K alpha-selective inhibitor CYH33 is mediated by genomic and transcriptomic alterations in ESCC cells 期刊论文 CELL DEATH & DISEASE, 2021, 卷号: 12, 期号: 1, 页码: 13 作者:  Wang, Yu-xiang;  Zhang, Xu;  Ma, Qing-yang;  Hu, Lan-dian;  Zhang, Xi 收藏  |  浏览/下载：47/0  |  提交时间：2021/05/24 PRMT1 is a novel molecular therapeutic target for clear cell renal cell carcinoma 期刊论文 THERANOSTICS, 2021, 卷号: 11, 期号: 11, 页码: 5387-5403 作者:  Wang, Jianfeng;  Wang, Chen;  Xu, Pan;  Li, Xiao;  Lu, Yongning 收藏  |  浏览/下载：129/0  |  提交时间：2021/05/24 clear cell renal cell carcinoma  protein arginine methyltransferase 1  therapeutic  lipocalin2 (LCN2)  sunitinib