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浏览/检索结果: 共12条，第1-10条 帮助 限定条件 发表日期：2020    专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 Large-scale Generation of Functional and Transplantable Hepatocytes and Cholangiocytes from Human Endoderm Stem Cells 期刊论文 CELL REPORTS, 2020, 卷号: 33, 期号: 10, 页码: 24 作者:  Feng, Sisi;  Wu, Jiaying;  Qiu, Wei-Lin;  Yang, Li;  Deng, Xiaogang 收藏  |  浏览/下载：40/0  |  提交时间：2021/05/24 Identify potent SARS-CoV-2 main protease inhibitors via accelerated free energy perturbation-based virtual screening of existing drugs 期刊论文 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2020, 卷号: 117, 期号: 44, 页码: 27381-27387 作者:  Li, Zhe;  Li, Xin;  Huang, Yi-You;  Wu, Yaoxing;  Liu, Runduo 收藏  |  浏览/下载：75/0  |  提交时间：2020/12/24 virtual screening  SARS-CoV-2  drug repurposing  free energy perturbation  main protease   Identification of SARS-CoV-2 entry inhibitors among already approved drugs 期刊论文 ACTA PHARMACOLOGICA SINICA, 2020, 页码: 7 作者:  Yang, Li;  Pei, Rong-juan;  Li, Heng;  Ma, Xin-na;  Zhou, Yu 收藏  |  浏览/下载：43/0  |  提交时间：2020/12/24 COVID-19  SARS-CoV-2  virus entry inhibitors  high throughput screening assay  approved drug library  histamine receptor antagonists  clemastine   A phase II randomized trial of sodium oligomannate in Alzheimer's dementia 期刊论文 ALZHEIMERS RESEARCH & THERAPY, 2020, 卷号: 12, 期号: 1, 页码: 10 作者:  Wang, Tao;  Kuang, Weihong;  Chen, Wei;  Xu, Wenwei;  Zhang, Liming 收藏  |  浏览/下载：63/0  |  提交时间：2020/12/21 Sodium oligomannate  Efficacy  Safety  Alzheimer's disease  Clinical trial   A phase II randomized trial of sodium oligomannate in Alzheimer’s dementia 期刊论文 Alzheimer's Research & Therapy, 2020, 卷号: 12, 期号: 1 作者:  Wang,Tao;  Kuang,Weihong;  Chen,Wei;  Xu,Wenwei;  Zhang,Liming 收藏  |  浏览/下载：70/0  |  提交时间：2020/12/24 Sodium oligomannate  Efficacy  Safety  Alzheimer’s disease  Clinical trial   Cryo-EM structure of an activated VIP1 receptor-G protein complex revealed by a NanoBiT tethering strategy 期刊论文 NATURE COMMUNICATIONS, 2020, 卷号: 11, 期号: 1, 页码: 10 作者:  Duan, Jia;  Shen, Dan-dan;  Zhou, X. Edward;  Bi, Peng;  Liu, Qiu-feng 收藏  |  浏览/下载：24/0  |  提交时间：2020/12/24 AMPK activator C24 inhibits hepatic lipogenesis and ameliorates dyslipidemia in HFHC diet-induced animal models 期刊论文 ACTA PHARMACOLOGICA SINICA, 2020, 页码: 8 作者:  Sun, Shui-mei;  Xie, Zhi-fu;  Zhang, Yang-ming;  Zhang, Xin-wen;  Zhou, Chen-dong 收藏  |  浏览/下载：26/0  |  提交时间：2020/12/24 adenosine 5 '-monophosphate-activated protein kinase  AMPK activator  C24  liver  triglycerides  cholesterol  VLDL  hypolipidemic drug  metabolic syndrome   Structural basis of GPBAR activation and bile acid recognition 期刊论文 NATURE, 2020, 页码: 29 作者:  Yang, Fan;  Mao, Chunyou;  Guo, Lulu;  Lin, Jingyu;  Ming, Qianqian 收藏  |  浏览/下载：46/0  |  提交时间：2020/12/24 Effect of phosphatidylcholine on the stability and lipolysis of nanoemulsion drug delivery systems 期刊论文 INTERNATIONAL JOURNAL OF PHARMACEUTICS, 2020, 卷号: 583, 页码: 9 作者:  Zhang, Bo;  Zhou, Xin;  Miao, Yunqiu;  Wang, Xiaoli;  Yang, Yuting 收藏  |  浏览/下载：16/0  |  提交时间：2020/12/24 Phosphatidylcholine  Nanoemulsion  Stability  Lipolysis kinetics  Curcumin   Synthesis and biological evaluation of heterocyclic bis-aryl amides as novel Src homology 2 domain containing protein tyrosine phosphatase-2 (SHP2) inhibitors 期刊论文 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2020, 卷号: 30, 期号: 11, 页码: 5 作者:  Satheeshkumar, Rajendran;  Zhu, Rui;  Feng, Bo;  Huang, Chao;  Gao, Ya 收藏  |  浏览/下载：29/0  |  提交时间：2020/07/01 Heterocyclic bis-aryl amides  PTP1B  SHP2  Inhibitors  Structure-activity relationships (SAR)