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科研机构
上海药物研究所 [16]
内容类型
期刊论文 [16]
发表日期
2020 [16]
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浏览/检索结果:
共16条,第1-10条
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发表日期:2020
专题:上海药物研究所
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Gigantol ameliorates CCl4-induced liver injury via preventing activation of JNK/cPLA2/12-LOX inflammatory pathway
期刊论文
SCIENTIFIC REPORTS, 2020, 卷号: 10, 期号: 1, 页码: 13
作者:
Xue, Yaru
;
Deng, Qiangqiang
;
Zhang, Qingli
;
Ma, Zhenghua
;
Chen, Binfan
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2021/05/24
Clinical application of pyrrole-hemoglobin adducts as a biomarker of pyrrolizidine alkaloid exposure in humans
期刊论文
ARCHIVES OF TOXICOLOGY, 2020, 页码: 7
作者:
Ma, Jiang
;
Zhang, Wei
;
He, Yisheng
;
Zhu, Lin
;
Zhang, Chunyuan
收藏
  |  
浏览/下载:41/0
  |  
提交时间:2020/12/24
Pyrrolizidine alkaloids
Liver injury
Diagnostic biomarkers
Pyrrole-hemoglobin adducts
Pyrrole-plasma protein adducts
Differential distribution of characteristic constituents in root, stem and leaf tissues of Salvia miltiorrhiza using MALDI mass spectrometry imaging
期刊论文
FITOTERAPIA, 2020, 卷号: 146, 页码: 9
作者:
Li, Shilin
;
Zhu, Nanlin
;
Tang, Chunping
;
Duan, Haonan
;
Wang, Yongwei
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2020/12/24
MALDI
Mass spectrometry imaging
Salvia miltiorrhiza
Salvianolic acid
Tanshinone
Repeated Nitrous Oxide Exposure Exerts Antidepressant-Like Effects Through Neuronal Nitric Oxide Synthase Activation in the Medial Prefrontal Cortex
期刊论文
FRONTIERS IN PSYCHIATRY, 2020, 卷号: 11, 页码: 11
作者:
Liu, Wei
;
Li, Qian
;
Ye, Binglu
;
Cao, Hang
;
Shen, Fuyi
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2020/12/21
nitrous oxide (N2O)
depression
mPFC
burst firing
neuronal nitric oxide synthase (nNOS)
BDNF
Repeated Nitrous Oxide Exposure Exerts Antidepressant-Like Effects Through Neuronal Nitric Oxide Synthase Activation in the Medial Prefrontal Cortex
期刊论文
FRONTIERS IN PSYCHIATRY, 2020, 卷号: 11, 页码: 11
作者:
Liu, Wei
;
Li, Qian
;
Ye, Binglu
;
Cao, Hang
;
Shen, Fuyi
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2020/12/21
nitrous oxide (N2O)
depression
mPFC
burst firing
neuronal nitric oxide synthase (nNOS)
BDNF
Identification and characterization of isocitrate dehydrogenase 1 (IDH1) as a functional target of marine natural product grincamycin B
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 13
作者:
Wang, Zheng
;
Li, Zeng-xia
;
Zhao, Wen-cao
;
Huang, Hong-bo
;
Wang, Jia-qi
收藏
  |  
浏览/下载:82/0
  |  
提交时间:2020/12/24
grincamycin B
marine natural product
isocitrate dehydrogenase 1
apoptosis
ER stress
intracellular ROS
Zebrafish embryos
hematological malignancies
Extracellular Vesicle-Mediated Delivery of Circular RNA SCMH1 Promotes Functional Recovery in Rodent and Nonhuman Primate Ischemic Stroke Models
期刊论文
CIRCULATION, 2020, 卷号: 142, 期号: 6, 页码: 556-574
作者:
Yang, Li
;
Han, Bing
;
Zhang, Zhiting
;
Wang, Shuguo
;
Bai, Ying
收藏
  |  
浏览/下载:87/0
  |  
提交时间:2020/12/24
circular RNA
extracellular vesicles
MeCP2 protein
neuronal plasticity
primate
stroke
Anti-SARS-CoV-2 activities in vitro of Shuanghuanglian preparations and bioactive ingredients
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 11
作者:
Su, Hai-xia
;
Yao, Sheng
;
Zhao, Wen-feng
;
Li, Min-jun
;
Liu, Jia
收藏
  |  
浏览/下载:115/0
  |  
提交时间:2020/12/24
SARS-CoV-2
3CL protease
traditional Chinese medicines
Shuanghuanglian oral liquid
baicalin
baicalein
Disrupting phosphatase SHP2 in macrophages protects mice from high-fat diet-induced hepatic steatosis and insulin resistance by elevating IL-18 levels
期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2020, 卷号: 295, 期号: 31, 页码: 10842-10856
作者:
Liu, Wen
;
Yin, Ye
收藏
  |  
浏览/下载:237/0
  |  
提交时间:2020/12/24
Src homology 2 domain containing tyrosine phosphatase-2 (SHP2)
hepatic steatosis
insulin resistance
caspase-1
interleukin 18 (IL-18)
fatty liver
metabolic disorder
inflammation
cytokine signaling
caspase 1 (CASP1)
tyrosine-protein phosphatase (tyrosine phosphatase)
macrophage
Dihydro-stilbene gigantol relieves CCl4-induced hepatic oxidative stress and inflammation in mice via inhibiting C5b-9 formation in the liver
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 14
作者:
Xue, Ya-ru
;
Yao, Sheng
;
Liu, Qian
;
Peng, Zhao-liang
;
Deng, Qiang-qiang
收藏
  |  
浏览/下载:60/0
  |  
提交时间:2020/07/01
gigantol
Chinese traditional medicine
liver injury
oxidative stress
inflammation
label-free proteomic
complement and coagulation cascades
terminal complement complex
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