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科研机构
上海药物研究所 [38]
内容类型
期刊论文 [38]
发表日期
2020 [38]
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浏览/检索结果:
共38条,第1-10条
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发表日期:2020
专题:上海药物研究所
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Anti-PD-L1 mediating tumor-targeted codelivery of liposomal irinotecan/JQ1 for chemo-immunotherapy
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 8
作者:
He, Zhi-di
;
Zhang, Meng
;
Wang, Yong-hui
;
He, Yang
;
Wang, Hai-rui
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2021/05/24
tumor-targeted delivery
immunogenic cell death
PD-1
PD-L1 blockade
tumor immune microenvironment
irinotecan
JQ1
immune checkpoint
Further new complex daphniphyllum alkaloids from the stems and leaves of Daphniphyllum calycinum: Structure and stereochemistry
期刊论文
TETRAHEDRON, 2020, 卷号: 76, 期号: 49, 页码: 8
作者:
Shen, Shou-Mao
;
Li, Heng
;
Wang, Jian-Rong
;
Zeng, Yan-Bo
;
Guo, Yue-Wei
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2020/12/24
Daphniphyllum calycinum
Daphniphyllum alkaloids
Absolute configuration
Co-delivery of all-trans-retinoic acid and doxorubicin for cancer therapy with synergistic inhibition of cancer stem cells (vol 37, pg 405, 2015)
期刊论文
BIOMATERIALS, 2020, 卷号: 263, 页码: 1
作者:
Sun, Rong
;
Liu, Yang
;
Li, Shi-Yong
;
Shen, Song
;
Du, Xiao-Jiao
收藏
  |  
浏览/下载:89/0
  |  
提交时间:2020/12/21
Crystallography-guided discovery of carbazole-based retinoic acid-related orphan receptor gamma-t (ROR gamma t) modulators: insights into different protein behaviors with "short" and "long" inverse agonists
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 11
作者:
Yu, Ming-cheng
;
Yang, Feng
;
Ding, Xiao-yu
;
Sun, Nan-nan
;
Jiang, Zheng-yuan
收藏
  |  
浏览/下载:85/0
  |  
提交时间:2020/12/24
RORγ
t
cocrystal structures
MD simulation
“
short”
inverse agonists
agonists
“
long”
inverse agonists
DW14006 as a direct AMPK alpha 1 activator improves pathology of AD model mice by regulating microglial phagocytosis and neuroinflammation
期刊论文
BRAIN BEHAVIOR AND IMMUNITY, 2020, 卷号: 90, 页码: 55-69
作者:
Lv, Jianlu
;
Wang, Wei
;
Zhu, Xialin
;
Xu, Xiaoju
;
Yan, Qiuying
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2020/12/21
Alzheimer'sdisease
Microglia
AMPK alpha 1
DW14006
Phagocytosis
Neuro-inflammation
Nostoc sphaeroids Kutz polysaccharide and powder enrich a core bacterial community on C57BL/6j mice
期刊论文
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2020, 卷号: 162, 页码: 1734-1742
作者:
Li, Meixia
;
Guo, Ciliang
;
Wang, Yeqing
;
Du, Zhenyun
;
Chen, Sheng
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2020/12/24
Nostoc sphaeroids Kutz polysaccharide
Nostoc sphaeroids Kutz powder
16S ribosomal RNA gene sequencing
Core bacterial community
New cembrane-type diterpenoids from the South China Sea soft coral Sinularia crassa and their alpha-glucosidase inhibitory activity
期刊论文
BIOORGANIC CHEMISTRY, 2020, 卷号: 104, 页码: 6
作者:
Wu, Meng-Jun
;
Wang, Hong
;
Jiang, Cheng-Shi
;
Guo, Yue-Wei
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2021/05/24
Sinularia crassa
Cembranoid
Modified Mosher's method
ECD calculation
alpha-Glucosidase inhibitor
A pectin-like polysaccharide from Polygala tenuifolia inhibits pancreatic cancer cell growth in vitro and in vivo by inducing apoptosis and suppressing autophagy
期刊论文
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2020, 卷号: 162, 页码: 107-115
作者:
Bian, Youcheng
;
Zeng, Hui
;
Tao, Hong
;
Huang, Lulin
;
Du, Zhenyun
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2020/12/24
Polygala tenuifolia
Pectin
Pancreatic cancer
Apoptosis
Autophagy
The impact of structural modification of sulfated polysaccharides on bone morphogenic protein 2 and inhibition of endothelial cell angiogenesis
期刊论文
CARBOHYDRATE RESEARCH, 2020, 卷号: 496, 页码: 10
作者:
Wang, Ying
;
Xiao, Fei
;
Jin, Can
;
Wang, Wucheng
;
Chen, Xia
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2020/12/21
Sulfated polysaccharides
Bone morphogenic protein 2
Structure and activity relationship
Angiogenesis
Polyprenylated acylphloroglucinols as deubiquitinating protease USP7 inhibitors from Hypericum hookerianum
期刊论文
FITOTERAPIA, 2020, 卷号: 146, 页码: 5
作者:
Wang, Qi-Qi
;
Wang, Xiao-Dong
;
Wu, Ling-Zhi
;
Fang, Qiang-Qiang
;
Liu, Ya-Nan
收藏
  |  
浏览/下载:44/0
  |  
提交时间:2020/12/24
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