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科研机构
生态环境研究中心 [49]
内容类型
期刊论文 [37]
学位论文 [10]
会议论文 [2]
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2020 [2]
2019 [4]
2016 [5]
2015 [3]
2014 [4]
2013 [5]
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环境科学::环境化学 [2]
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First unequivocal identification of the critical acyl radicals from the anti- tuberculosis drug isoniazid and its hydrazide analogs by complementary applications of ESR spin-trapping and HPLC/MS methods
期刊论文
FREE RADICAL BIOLOGY AND MEDICINE, 2020, 卷号: 154, 页码: 1-8
作者:
Qin, Li
;
Huang, Chun-Hua
;
Mao, Li
;
Shao, Bo
;
Zhu, Ben-Zhan
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2021/09/14
Isoniazid
Hydrazides
Carbon-centered acyl radicals
ESR spin-trapping/HPLC/MS
N-tert-butyl-alpha-phenylnitrone (PBN)
NAD(+) adducts
Unexpected activation of N-alkyl hydroxamic acids to produce reactive N-centered free radicals and DNA damage by carcinogenic chlorinated quinones under normal physiological conditions
期刊论文
FREE RADICAL BIOLOGY AND MEDICINE, 2020, 卷号: 146, 页码: 70-78
作者:
Huang, Chun-Hua
;
Xu, Dan
;
Qin, Li
;
Tang, Tian-Shu
;
Shan, Guo-Qiang
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2021/09/14
N-alkyl hydroxamic acids
N-centered radicals
Chlorinated quinones
Carbon-nitrogen bonding conjugate
DNA adducts
Sulfur-centered hemi-bond radicals as active intermediates in S-DNA phosphorothioate oxidation
期刊论文
NUCLEIC ACIDS RESEARCH, 2019, 卷号: 47, 期号: 22, 页码: 11514-11526
作者:
Jie, Jialong
;
Xia, Ye
;
Huang, Chun-Hua
;
Zhao, Hongmei
;
Yang, Chunfan
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  |  
浏览/下载:15/0
  |  
提交时间:2020/09/10
Liquid chromatography- mass spectrometry for analysis of DNA damages induced by environmental exposure
期刊论文
TRAC-TRENDS IN ANALYTICAL CHEMISTRY, 2019, 卷号: 120, 页码: -
作者:
Yin, Junfa
;
Zhang, Ning
;
Wang, Hailin
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  |  
浏览/下载:106/0
  |  
提交时间:2020/09/10
DNA damage
DNA modification
Liquid chromatography-mass spectrometry
Environmental exposure
Environmental health
Mechanism of unprecedented hydroxyl radical production and site-specific oxidative DNA damage by photoactivation of the classic arylhydroxamic acid carcinogens
期刊论文
CARCINOGENESIS, 2019, 卷号: 40, 期号: 9, 页码: 1153-1163
作者:
Xu, Dan
;
Huang, Chun-Hua
;
Xie, Lin-Na
;
Shao, Bo
;
Mao, Li
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2020/09/10
Occurrence and Degradation Potential of Fluoroalkylsilane Substances as Precursors of Perfluoroalkyl Carboxylic Acids
期刊论文
ENVIRONMENTAL SCIENCE & TECHNOLOGY, 2019, 卷号: 53, 期号: 9, 页码: 4823-4831
作者:
Zhu, Bao
;
Jiang, Wei
;
Wang, Wenxing
;
Lin, Yongfeng
;
Ruan, Ting
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2020/10/21
Experimental and Theoretical Evidence for Diastereomer- and Enantiomer-Specific Accumulation and Biotransformation of HBCD in Maize Roots
期刊论文
ENVIRONMENTAL SCIENCE & TECHNOLOGY, 2016, 卷号: 50, 期号: 22, 页码: 12205-12213
作者:
Huang, Honglin
;
Zhang, Shuzhen
;
Lv, Jitao
;
Wen, Bei
;
Wang, Sen
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  |  
浏览/下载:22/0
  |  
提交时间:2017/03/27
环状异羟肟酸及衍生物与多卤代醌反应机理研究
学位论文
博士, 北京: 中国科学院研究生院, 2016
作者:
李锋
收藏
  |  
浏览/下载:131/0
  |  
提交时间:2017/07/11
四氯苯醌,N-羟基吡啶酮,N-羟基吡啶硫酮,N-羟基邻苯二甲酰亚胺, 糖精钠
Tetrachloro-1,4-benzoquinone (TCBQ), N-hydroxypyridone (NHP), N-hydroxypyrithione (NHPT), N-hydroxyphthalimide (NHPI), saccharin sodium
Detection of 1,N-2-propano-2 '-deoxyguanosine in human urine by stable isotope dilution UHPLC-MS/MS analysis
期刊论文
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2016, 卷号: 1023, 期号: 0, 页码: 68-71
作者:
Zhang, Ning
;
Song, Yuanyuan
;
Zhang, Weibing
;
Wang, Hailin
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2017/03/27
1,N-2-propano-2 '-deoxyguanosine adducts
Human urine
SPE
UHPLC-MS/MS
Detection of of 1,N-2-propano-2 '-deoxyguanosine adducts in genomic DNA by ultrahigh performance liquid chromatography-electrospray ionization-tandem mass spectrometry in combination with stable isotope dilution
期刊论文
JOURNAL OF CHROMATOGRAPHY A, 2016, 卷号: 1450, 期号: 0, 页码: 38-44
作者:
Zhang, Ning
;
Song, Yuanyuan
;
Wu, Danni
;
Xu, Tian
;
Lu, Meiling
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2017/03/27
Crotonaldehyde (Cro)
1,N-2-propano-2'-deoxyguanosine adducts (ProdG adducts)
Ultrahigh performance liquid chromatography-electrospray ionization-tandem mass spectrometry (UHPLC-ESI-MS/MS)
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